Which part of heart serves as an effector, Biology

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Which of the following serves as an effector, or as part of an effector, that functions in a negative feedback system?

A. Nicotinic Acetylcholine Receptors (nAChR) in SA node cells of the heart.

B. F-channels in the cells of the AV valves of the heart.

C. Alpha-adrenergic Receptors in smooth muscles surrounding the arterioles.

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