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A substitution mutation occurs in the GRE making it unrecongnizable to the glucocorticoid receptor. What impact would this have on the transcription of the gene downstream of this element?
-reduced transcription downstream
-increase transcription downstream
-no change to transcription, increased translation
Database Search: Once an open reading frame or the partial amino acid sequence has been pre-determined, the investigator compares sequence with others in the databases using a com
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Early human studies are normally conducted in healthy subjects to assess acute safety and, if applicable, to monitor biochemical and pharmacological responses. These studies also p
respiration through moist skin
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