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Prostaglandins and the structurally associated molecules prostacyclins, leukotrienes and thromboxanes, are called as eicosanoids because they having 20 carbon atoms. These hormones are associativaly short-lived and thus act locally near to their site of synthesis in the body. They are derived from the common precursor arachidonate described in the figure. This polyunsaturated fatty acid is a derivative of linoleate .The Prostaglandins encourage inflammation, modulate synaptic transmission between nerve cells, and induce sleep. Whereas aspirin (acetylsalicylic acid) has been used for centuries to reduce inflammation, fever and pain, it was not until year of 1974 which John Vane discovered how aspirin works. Aspirin hold back the synthesis of prostaglandins by irreversibly inhibiting prostaglandin synthase. This enzyme catalyzes the first phase in the synthesis of prostacyclins and thromboxanes, prostaglandins.
Figure: Biosynthetic relationship of the eicosanoids.
Which type of reproductive structure has a better chance of survival if there was a sudden temperature change in its environment?
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Hypothermia : Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At norma
Roan (RW) is a color of cattle in which both red and white hairs are present due to codominance. What are the phenotype and genotype ratios of offspring produced by: roan bull and
What is an accommodation? Accommodation is the ability of the eye to focus on an object situated at variable distances from the eye. Like a camera, even the eye requires to cha
A 70-year old woman presents with a 1-hour history of crushing substernal chest pain. Shortly after admission, the patient expires. An autopsy reveals calcium deposits in the intim
A fish of genotype a/a; B/b is crossed to a fish whose genotype is A/a; B/b. What proportion of the progeny will be heterozygous for at least one of the genes? (Assume independent
Which one of the following structures between two adjacent cells is an effective transport pathway? 1. Plasmodesmata 2. Plastoquinones 3. Endoplasmic reticulum 4. Plasm
Subphylum Opalinata Body covered with longitudinal rows of cilium like ,organelles but true ciliature absent. Parasitic; cytosome lacking; two to many nuclei of one type.
Blood Collection: Blood for analysis may be obtained from veins, arteries, or capillaries. Venous blood is usually the specimen of choice, and venipuncture is the method for
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