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Prostaglandins and the structurally associated molecules prostacyclins, leukotrienes and thromboxanes, are called as eicosanoids because they having 20 carbon atoms. These hormones are associativaly short-lived and thus act locally near to their site of synthesis in the body. They are derived from the common precursor arachidonate described in the figure. This polyunsaturated fatty acid is a derivative of linoleate .The Prostaglandins encourage inflammation, modulate synaptic transmission between nerve cells, and induce sleep. Whereas aspirin (acetylsalicylic acid) has been used for centuries to reduce inflammation, fever and pain, it was not until year of 1974 which John Vane discovered how aspirin works. Aspirin hold back the synthesis of prostaglandins by irreversibly inhibiting prostaglandin synthase. This enzyme catalyzes the first phase in the synthesis of prostacyclins and thromboxanes, prostaglandins.
Figure: Biosynthetic relationship of the eicosanoids.
A n a e m i a It is defined as decrease in the amount of haemoglobin (Hb) per unit of blood. This may or may not be accompanied by a reduction in the red blood cells (RBC
Can someone explain how is cancer related to ras and p53 gene? I know that the ras protein regulate cell growth and its mutation will cause cancer. How is the mutation caused?
Cytoplasmic bridge formed during the conjugation of paramoec: The two paramoecia that undergo conjugation are called conjugants. During conjugation, the two conjugants com
a) Name two food additives needed to keep food wholesome, and say what they do. b) Name two food additives (or types of additive) which are not necessary for keeping fo
Explain the Occurrence of vitamin B 6 Vitamin B 6 activity is attributed to the 3 compounds-pyridoxol (pyridoxine), pyridoxal and pyridoxamine, generally comprised in the vit
How are grasslands classified? Grasslands might be classified into steppes and savannahs. In the steppes the prevailing vegetation is grass, as in the pampas of South America
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How do adhesion and cohesion help plants move materials?
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What is the life cycle of the hookworms? Adult hookworms within the human intestine release eggs that are eliminated with the human feces. Under adequate conditions of moisture
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