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What is Pancreatic lipase
Pancreatic lipase acts on the dietary triacylglycerols after it has been incorporated into the mixed micelle in the intestinal lumen. The lipase acts at interface between water and the triacylglycerol molecules, and its catalytic action is facilitated by the presence of colipase (a small protein cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis), which is also produced by the pancreas. Pancreatic lipase is specific for the fatty acid residues at positions 1 and 3 of the glyceryl moiety thus releasing 2-monoacylglycerol and two fatty acids from a triacylglycerol molecule. The final digestive products of triacylglycerol digestion are free fatty acids, glycerol and monoacylglycerols.
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