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Cholesterol is the precursor of the five major classes of steroid hormones.The synthesis of steroid hormones is initiated by the removal of a six-carbon unit from carbon 20 of the cholesterol side chain to form pregnenolone, the ordinary precursor of all steroid hormones. A series of reactions catalyzed by cytochrome P450 change pregnenolone to give increase to the individual hormones.
Figure: Biosynthetic pathway for the synthesis of the steroid hormones.
Define Fluconazole It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclospor
Manifestations of anemia that are directly due to the diminished oxygen-carrying capacity of hemoglobin include: Answer A. pale skin. B. bleeding. C. bone pain. D. fatigue.
Define Changes associated with the skeletal system - Ageing? Skeletal bone loss occurs with ageing and may have serious consequences among the elderly. With ageing, there is so
There is a wide spectrum of potential clinical presentations with heart failure. Most patients have signs and symptoms of pulmonary congestion including dyspnea, orthopnea, and par
An enhance in parasympathetic discharge to the heart leads to A. An enhance in the conductance of F-channels in SA node cells. B. An enhance in the conductance of potassium
What are the main functions of the bacterial flora within the human gut? Bacteria that live inside the gut have great significance in digestion. Some polysaccharides like cellu
How does iodine kill germs? The microbiocidal action of Iodine is because of the active form, I2, which is polarized by water and like all halogens (chlorine, fluorine, bromine
Possible causes of elevated triglycerides: - Obesity - Alcohol - Uncontrolled diabetes - Hypothyroidism - Genetic - Liver disease - Drugs Possible causes o
How light reaction effects Cell Metabolism ? Light reactions : The light reactions are carried out by two separate assemblies of several hundred chlorophyll molecules, acces
Copper deficiency Copper deficiency may be primary or secondary (conditional). Primary copper deficiency occurs due to its inadequate dietary intake; whereas secondary copper d
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