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Cholesterol is the precursor of the five major classes of steroid hormones.The synthesis of steroid hormones is initiated by the removal of a six-carbon unit from carbon 20 of the cholesterol side chain to form pregnenolone, the ordinary precursor of all steroid hormones. A series of reactions catalyzed by cytochrome P450 change pregnenolone to give increase to the individual hormones.
Figure: Biosynthetic pathway for the synthesis of the steroid hormones.
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