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Cholesterol is the precursor of the five major classes of steroid hormones.The synthesis of steroid hormones is initiated by the removal of a six-carbon unit from carbon 20 of the cholesterol side chain to form pregnenolone, the ordinary precursor of all steroid hormones. A series of reactions catalyzed by cytochrome P450 change pregnenolone to give increase to the individual hormones.
Figure: Biosynthetic pathway for the synthesis of the steroid hormones.
DNA binding domains called as basic domains rich in basic amino acids that was happen in transcription factors in combination with zipper helix-loop-helix or leucine (HLH) dimeriza
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