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Valvular Heart Diseases
Normal heart valves function to maintain a uni-directional flow of blood through cardiac chambers. Two basic problems that compromise the normal function of the valves are stenosis and insufficiency. Stenosis is a thickening of valvular tissue. causing a narrowing of the valvular opening. Insufficiency refers to the inability of the valve to close completely, allowing blood to regurgitate.
Causes
Predominant causative factor is rheumatic fever.
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Pathophysiology Large haemorrhages and fibrinous lesions vegetate along the inflaked edges of valves. The lesions develop on adjacent valve leaflets so that the edges adh
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