Tubercular meningitis , Biology

Assignment Help:

Tubercular Meningitis (TBM)

Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosis. It may appear within one year of primary infection with tuberculosis and may lead serious disabling neurological sequelae.

Pathophysiology

The tubercular meningitis result due to hematogenous spread from primary leison. A submeningial tuberculoma may form which discharges tubercle bacilli in the subarachnoid space. The bacilli proliferate and cause perivascular exudation followed by caseation, gliosis and giant cell formation.

The meningial surface is covered with yellow greyish tubercles, usually along the course of the vessels which are more numerous in temporal lobe and along the course of middle cerebral artery. The ventricles get dilated resulting in obliteration of subarachnoid space and the arachnoid villi leading to increase in formation of cerebrospinal fluid. The foramina also get blocked with gelatinous exudate which interferes with CSF circulation and causes hydrocephalus. There is cereberal oedema which results in tuberculous encephalopathy.


Related Discussions:- Tubercular meningitis

Technique of operation, Technique of Operation :  TEE probe i...

Technique of Operation :  TEE probe is passed in all cases soon after anaesthesia. The initial steps and exposure of mitral valve are done as for open mitral valvotom

What are the uses of construction of a retaining wall, What are the uses of...

What are the uses of construction of a retaining wall? The retaining wall is constructed whenever space requirement do not allow the natural slope to be formed for an excavatio

Senescence - effects of plant growth regulators, Senescence - Effects of Pl...

Senescence - Effects of Plant Growth Regulators on Development All five major growth regulator groups: auxins, gibberellins cytokinins, abscisic acid and ethylene can influenc

Ameoba, what is the scientific name of ameoba

what is the scientific name of ameoba

What do you mean by nervous system, Q. What do you mean by Nervous System? ...

Q. What do you mean by Nervous System? Structural Organization:   CNS + PNS Functional Organization:   only concerned with PNS Sensory (Afferent) ->  CNS Motor (Effe

Hypothalamus and pituitary, Hypothalamus and Pituitary The most obviou...

Hypothalamus and Pituitary The most obvious neuroendocrine link is between the hypothalamus and pituitary. The hypothalamus is a part of the brain which is connected to the pi

Enumerate various factors controlling osseointegration, Q. Enumerate variou...

Q. Enumerate various factors controlling osseointegration? The factors controlling osseointegration are: i) Occlusal load ii) Biocompatibility of the material iii) Imp

Physiology and biochemistry evidences, PHYSIOLOGY AND BIOCHEMISTRY - ...

PHYSIOLOGY AND BIOCHEMISTRY - Ample and concrete evidence of organic evolution are obtained from the functional activity and chemical composition of animals. J.B.S. Hald

Explain about chlorophylls - natural pigments, Explain about Chlorophylls ...

Explain about Chlorophylls Chlorophylls are used as colourants in a range of foodstuffs and both natural chlorophyll (containing magnesium as the central metal ion) and 'coppe

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd