Transmissible gastroenteritis of swine

The disease, first reported from the USA in 1964, is caused by antigenic group 1 mamalian coronavirus, a member of genus Coronavirus of family Coronaviridae and usually occurs during winter. The disease is responsible for high level of piglet mortality.

Clinical signs: Four distinct disease patterns seen in swines- vomitting and wasting disease; porcine epidemic diarrhoea; TGE and respiratory disease. Clinical signs are most severe in piglets, with vomiting followed by profuse yellow diarrhoea with weight loss and dehydration.

Diagnosis: It is diagnosed by the clinical manifestations and high fatality rate among piglets and an explosive outbreak of vomition and copious diarrhoea. The disease is confirmed in the laboratory by FAT, virus isolation in cell culture and demonstration of rising antibody titers in paired sera.
Prevention and control: Good management of farrowing house, vaccinating sows with an attenuated vaccine before farrowing are the methods available for controlling this infection.