Target organ damage, Biology

Assignment Help:

Central Nervous System  

Hypertension is one of the leading causes of cerebrovascular disease. It has been associated with accelerated age related cognitive decline. The most dreaded  complication  is the occurrence of  strokes. The risk of a stroke increases almost 4 fold in a person with a diastolic pressure of 91 to one with 105 mmHg. Transient ischemic attacks (TIA) do occur due to extracranial atherosclerosis.

Renal

Hypertension induces microalbuminuria in the early stages. Later on nephrosclerosis sets in leading to renal failure with rise in blood urea and creatinine.

Aorta

The commonest abnormality of the aorta, associated with hypertension is abdominal  aneurysms. This can eventually lead on to rupture with fatal results.

Eye

The changes in the eye can be identified and assessed by fundus examination. Keith Wagner classification is the usual method of grading.

Grade I: Narrowing of arteries giving rise to copper wire or silver wire appearance.

Grade II: In addition to copper wire appearance,  arterio-venous nipping where the arteries cross the veins.

Grade III : In addition to above, superficial flame shaped and deep dot like haemorrhages and cotton wool exudates.

Grade IV : In addition to all the above, papilloedema.


Related Discussions:- Target organ damage

Determine the procedure of armamentarium, Determine the Procedure of Armame...

Determine the Procedure of Armamentarium 1. Make an impression of the mandibular ridge and pour the cast in type 3 gypsum 2. Apply separating medium and allow it to dry 3

Zygotic or suspensor polyembryony, Zygotic or Suspensor Polyembryony ...

Zygotic or Suspensor Polyembryony Cleavage of the apical cells of the globular or filamentous proembryo produced by the zygote may result in two or more embryos in a seed. Th

Define management of parkinson''s disease, Define Management of Parkinson...

Define Management of Parkinson's Disease - Drug, Feeding and Nutritional Care? There is no cure yet for Parkinson's disease, but its symptoms can be minimized with drug thera

Cardiac care on admission for operation, Cardiac Care on Admission (First t...

Cardiac Care on Admission (First two hours) ECG is monitored by more than one lead (three to five). Left atrial pressure, arterial BP, central venous pressure, respiration

Explain the working of pulmonary circulation, Explain the working of Pulmon...

Explain the working of Pulmonary Circulation? In pulmonary circulation, blood is pumped to the lungs, where carbon dioxide is exchanged for oxygen. Blood returning from the bod

How the body gets rid of dust which enters the lungs, Using the words 'cili...

Using the words 'cilia' and 'mucus', describe, very briefly, how the body gets rid of dust which enters the lungs. The lining of the air passages makes mucus which traps dust p

Oxygen - factors influencing functions of nitrogenase, Oxygen - Factors Inf...

Oxygen - Factors Influencing Functions of Nitrogenase Oxygen is a strong inhibitor of N 2 -fixation because it blocks both the synthesis as well as the activity of nitrogenase

Define sodium, Define Sodium, Potassium and Chloride - Minerals? Claude...

Define Sodium, Potassium and Chloride - Minerals? Claude Bernard was the first to draw attention to the internal environment (milieu interior), referring to the extracellular f

Biosynthesis of cholesterol, Animals are able to synthesize cholesterol de ...

Animals are able to synthesize cholesterol de novo by an elegant series of reactions in that all 27 carbon atoms of cholesterol are derived from acetyl CoA. The  acetate  units  ar

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd