SPLEEN

• Largest lymph gland, also with myeloid tissue is an important specialized reticuloendothelial organ in vertebrates, as the site of erythropoiesis.
• Splenic tissue is distinct as white pulp and red pulp with blood spaces and lymph channels (= cords of Billroth) within it.
• In adult mammals the myeloid tissue degenerates the red pulp only stores RBC and white pulp forms macrophages and lymphocytes.
• In mammals it is a flat elongated structure attached to hind border of stomach.
• Its connective tissue capsule also traverses inside as septa (trabaculae) and divide the lnner mass into several incomplete lobules, which are better developed in mamma]s than in frog.
• Called as graveyard of RBC and blood bank Ist.