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Aldosterone mediates myocardial remodeling and fibrosis, as well as sodium retention and potassium loss at the distal tubules. The anti-aldosterone agent, spironolactone has been shown in RALES trial as an important neuro-hormonal antagonist in the treatment of heart failure. In this trial spironolactone 25 mg daily was compared with placebo in patients with advanced heart failure already receiving ACE inhibitors and diuretics and showed a 29 per cent reduction in mortality.
Q. What is Homocystinuria? Homocystinuria may result from errors of methionine metabolism. This produces defects in the function of cystathionme b synthase or 5-mcthyltctrahyd
Define Excretion of toxins and Act as precursors? Excretion of toxins: Glucuronic acid, a metabolite of glucose, combines with chemical and bacterial toxins and some normal met
Bone Modeling It is a surface-specific activity (apposition or resorption) that produces a net change in the size and/or shape of a bone after initial bone formation in the emb
Describe the procedures involved in blood doping. What are the physiological mechanisms behind blood doping that attempt to achieve the desired outcome(s).
What is NADP and NADPH? NADP is the abbreviation of the nicotinamide adenine dinucleotide phosphate cation, a hydrogen acceptor. NADPH is made when NADP binds to one hydrogen a
Define Stolon - Types of Hyphae? Microscopically, hyphae are aseptate and coenocytic. There are 3 kinds of hyphae: (a) Stolon - These grow horizontally on substratum surfa
Q. Bracketed Keys to identifying plants and animals? In bracketed keys two couplet leads of the same rank are bracketed together. The alternative clues or couplets are written
Accidents and Losses Accident can be considered as an incident occurring without intention and results in injury, loss of body part or even death of a human being or a few per
Things to do- We ought to aide by earthquake resisting building codes during construction and retrofitting of existing buildings. We should have a first AID box handy and learn
Biogeochemical Cycling - Nutrient Cycles The energy flows through ecosystems enabling the organisms to perform various kinds of work, and is ultimately lost as heat. It is gon
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