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Aldosterone mediates myocardial remodeling and fibrosis, as well as sodium retention and potassium loss at the distal tubules. The anti-aldosterone agent, spironolactone has been shown in RALES trial as an important neuro-hormonal antagonist in the treatment of heart failure. In this trial spironolactone 25 mg daily was compared with placebo in patients with advanced heart failure already receiving ACE inhibitors and diuretics and showed a 29 per cent reduction in mortality.
Explain the Work of John Ray in Animal Taxonomy? The first important work on both animal and plants was initiated by John Ray (1627-1705). He followed Aristotle and divided ani
Effects on Materials - Air pollutants Most air pollutants are reactive chemicals, so they react with most of the substances around. You may recall from your chemistry lessons
The modern water treatment plan is often called upon to perform wonders with the water fed to it. The clear, safe , even tasteful water that comes from a faucet may have started a
Q. Where in eukaryotic cells does mRNA synthesis take place? To where do these molecules migrate? Messenger RNA molecules are synthesized within the nucleus, pass through gain
Explain about the term- Therapeutic Therapeutic approaches that scientists are pursuing include transplanting cells to replace those which are damaged or using growth factors
Growth and Development of Plants You must have seen beautiful plants growing in pots in a garden. The plant grows while the pot does not. As a rule living things grow, but non
Heat Production In the Homeotherms heat production must be elevated if the ambient temperature falls below the critical temperature. Although all metabolic processes result i
Explain Methodology Required for Osazone Test? Take about 250-300 mg of phenylhydrazine mixture in the 3 clean labelled 15 ml dry test tubes. Add 5 ml of the glucose, fructose
Can stroke be prevented Brain experts are convinced that several strokes can be prevented with proper attention to lifestyle factors which increase risk, including smoking, exc
What happens during aerobic respiration to the pyruvic acid molecules made by glycolysis? What is the sequence of reactions that then follows? The pyruvic acid molecules made i
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