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Aldosterone mediates myocardial remodeling and fibrosis, as well as sodium retention and potassium loss at the distal tubules. The anti-aldosterone agent, spironolactone has been shown in RALES trial as an important neuro-hormonal antagonist in the treatment of heart failure. In this trial spironolactone 25 mg daily was compared with placebo in patients with advanced heart failure already receiving ACE inhibitors and diuretics and showed a 29 per cent reduction in mortality.
Q. Show the parameters which are of interest in CHD? Total Cholesterol: Serum totnl cholesterol equals the sum of HDL-cholesterol (HDL-c), VLDL-cholesterol (VLDL-c) and LDL-cho
Number of Implants The use of more implants decreases the number of pontics and the associated mechanics and strains on the prosthesis, and dissipates stresses more effectively
Determine the types of symbols used in Soil Horizons Three kinds of symbols are used in various combinations to designate horizons. These are capital letters, lower case lett
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Define about the Micro Minerals? Micro minerals are those minerals, which comprise less than 0.01% of the total body weight and are required in concentrations of one part per m
HMP shunt in erythrocytes HMP shunt in erythrocytes is of importance due to the generation of NADPH, which maintains the glutathione (G-SH) in the reduced state by glutathi
Q. How does the plant cell wall act in response when it is placed under hypotonic medium? The plant cell wall (the covering of the cell external to the cell membrane) is made o
What are the main features of the meristematic cells? Why do these cells require to have a high mitotic rate? Meristematic cells have very thin cell walls, small vacuoles, a w
COMPOSITION OF CELL WALL Cell wall composed of cellulose, hemicellulose, pectin, lignin, cutin & chitin. Cell wall consists of 3 parts - 1. Matrix Highly cross-
Q. What are the major endocrine glands of the human body? The major endocrine glands of the human body are the hypophysis (or pituitary), the pineal gland (or pineal body), the
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