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Aldosterone mediates myocardial remodeling and fibrosis, as well as sodium retention and potassium loss at the distal tubules. The anti-aldosterone agent, spironolactone has been shown in RALES trial as an important neuro-hormonal antagonist in the treatment of heart failure. In this trial spironolactone 25 mg daily was compared with placebo in patients with advanced heart failure already receiving ACE inhibitors and diuretics and showed a 29 per cent reduction in mortality.
Q. Of which kind of tissue is the heart made? How is this tissue oxygenated and nutrified? The heart is made of striated cardiac muscle tissue and the heart muscle is called th
Leptospirosis Synonyms: Weil’ disease, canicola fever, 7-day fever Leptospirosis is an important and widespread zoonosis. It was first described by Adolf Weil in 1886 when h
What are the different mechanisms responsible for corneal avascularity? Various mechanisms responsible for its avascularity are as follows: a) Chemical Theory: I) Role o
In the early days of microbiology, the disease producing submicroscopic agents were termed as 'filterable viruses' because of their ability to pass through conventional filters whi
describe the different types of genomes that viruses can have
What is the primary energy source for life on earth? The primary energy resource for life on earth is the sun. The sun plays the vital role of keeping the planet warmed and it
Define Excretion of toxins and Act as precursors? Excretion of toxins: Glucuronic acid, a metabolite of glucose, combines with chemical and bacterial toxins and some normal met
Explain Micafungin sodium Micafungin sodium (Mycamine - Astellas), the second echinocandin antifungal1 to become available in the US, has been approved by the FDA for intraveno
What is the tree girdling? What happens to the plant when that girdle is removed from the stem (below the branches)? Tree girdling or Malpighi's girdling is the removal from a
Using examples of invertebrate nervous systems how can the process of evolutionary cephalization be described? Considering the instance of invertebrates it is observed that ev
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