Spironolactone, Biology

Assignment Help:

Aldosterone mediates myocardial remodeling and fibrosis, as well as sodium retention and potassium loss at the distal tubules. The anti-aldosterone agent, spironolactone   has been shown in RALES trial as an important neuro-hormonal antagonist in the treatment of heart failure. In this trial spironolactone 25 mg daily was compared with placebo in patients with advanced heart failure already receiving ACE inhibitors and diuretics and showed a 29 per cent reduction in mortality.


Related Discussions:- Spironolactone

Determine the principles of suturing, Determine the Principles of suturing ...

Determine the Principles of suturing These are universal principles which are applicable in all aspects not just implant surgery: 1. Sutures should always be inserted throug

Obelia, why obelia shows an intermediate grade of organisation

why obelia shows an intermediate grade of organisation

Identical chromatids or separation of homologous chromosomes, Q. During mit...

Q. During mitotic anaphase is there separation of identical chromatids or separation of homologous chromosomes? In the anaphase of mitosis the identical chromatids complete and

Fats , FATS ( = True Fats, Triglycerides, Neutral Fats) They are es...

FATS ( = True Fats, Triglycerides, Neutral Fats) They are esters of fatty acids and 3-carbon trihydric alcohol glycerol (= glycerine). T rue fat is also called trig

Theory of evolution and its rival theories try to solve, What is the proble...

What is the problem that the theory of evolution and its rival theories try to solve? The problem that the theory of simply evolution, or evolution, and its rival theories try

In which area dietitians works, In which area Dietitians works Dietitia...

In which area Dietitians works Dietitians can work in a variety of areas, as already mentioned earlier, many of these are in the  Hospitals or in  the community  as  'Clinical

Methods of control of air pollution, The best way to maintain quality of ai...

The best way to maintain quality of air and pollutant's emissions is by using less polluting fuels and processes. Following can be taken to control air pollution. Source correc

Conformational protection - azotobacter, Conformational Protection - Azotob...

Conformational Protection - Azotobacter In conformational protection a Fe-S redox protein provides protection to the enzyme. The protein gets oxidised in the presence of oxyge

Anticoagulant therapy, Anticoagulant therapy To prevent blood clottin...

Anticoagulant therapy To prevent blood clotting on the valve, patients with prosthetic valves require life long anticoagulant therapy. The patient is put on oral antico

Illustrate the conductance of potassium channels, A decrease in parasympath...

A decrease in parasympathetic discharge to the heart leads to A. an increase in the conductance of F-channels in SA node cells. B. a decrease in the conductance of potassium

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd