Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
All the cells present in the body contain genes and an approach targeted to modulate the expression of genes is known as gene therapy. This novel approach has emerged by the end of 20th century and comes up with a promise of treating a large number of genetic disorders by ultimately modifying the gene expression (Jin et al, 2008). The two forms of gene therapy are somatic and germ line.
Somatic gene therapy: During this therapeutic approach, the genetic diseases are treated by inserting recombinant genes into non-reproductive or somatic cells. This kind of approach is limited to the patient and does not get transmitted to the future generations of. A normal copy of the malfunctioning gene is inserted into the mutant cells due to which an improvement in the disease phenotype is observed (Dorin, 1996). In the recent past, this technique has been found to be successful in case of familial hypercholesterolaemia and adenosine deaminase deficiency. For treating these disorders hepatocytes and T cells have been used for gene transfer respectively (Dorin, 1996). It has also shown significant success in case of cystic fibrosis and cancer. Various vehicles, like viral and non viral vectors help in the introduction of the genetic material into the mutated cells (Elias and Annas, N.D). This therapeutic approach is categorized into three sections:
However this approach produces short term results as the tissues die and get replaced with other cells.
Necessity of Transport in Phloem Leaves produce photoassimilates and support various tissues including roots. The excess photoassimilates and metabolites stored in specialised
Q. Understanding Behaviour of diabetic patients? Beliefs Each of us has a set of beliefs that were learned by us when we were young. These include religious beliefs and
Cotyledon is a leaf-like structure which is present in the seeds of the flowering plants; it appears during seed germination and sometimes is referred to as the seed leaf.
Campylobacteriosis The genus Campylobacter has been long associated with the cause of veterinary diseases under different names. It is only in the last 30 years that these org
What evidence is there that makes it seem humans have more than a material existence?
5. Maple syrup urine disease is a rare inborn error of metabolism. It derives its name from the odor of the urine of affected individuals. If untreated, affected children die soon
How are mineral salts, water and food (sugar) transported throughout the plant? Mineral salts, Water and sugar are transported throughout the plant through conductive vessels f
Define Reagents for Estimation of Calcium Using EDTA Titrimetric Method? 1. Buffer solution: Dissolve 16.9 g NH 4 CI in 143 ml NH 4 OH. To this add 50 ml of solution containing
defination of phyletic lineage?
differenciate between plasma and serum
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd