Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

How inadequate breast milk cause protein energy malnutrition, How Inadequat...

How Inadequate Breast Milk cause protein energy malnutrition? Though prolonged breastfeeding of children is the rule in US, the amount of breast milk secreted in poor Indian mo

Basic principles involved ark, Q. Basic principles involved ark? The ba...

Q. Basic principles involved ark? The basic principles involved ark: The individual must be treated as such and for that careful initial history - daily living situation, a

Explain the effect of deficiency of pyridoxine, Explain the effect of Defic...

Explain the effect of Deficiency of pyridoxine? A deficiency of vitamin B6 alone is uncommon because it usually occurs in association with a deficit in other B-complex vitamin

State the designations for horizons, State the Designations for Horizons  ...

State the Designations for Horizons  Of the several horizons, the master horizons are the results of the fundamental soil forming processes, viz. humification, eluviation  and

Explain the flow phase of stress response, Explain the Flow Phase of Stress...

Explain the Flow Phase of Stress Response? This is a neuro-endocrine response to physiological stress following the ebb phase. This phase is characterized by: Normal or

Organic compounds, ORGANIC COMPOUNDS - They are substances having bo...

ORGANIC COMPOUNDS - They are substances having both carbon and hydrogen which are commonly biological in origin. Organic compounds can be micromolecules or macromolecules

What are rna polymerase subunits, Each of the three eukaryotic RNA polymera...

Each of the three eukaryotic RNA polymerases has more subunits or 12 and so these are big complex enzymes. The genes encoding some of the subunits of each  eukaryotic  enzyme  show

Explain serum lipoprotiens, Explain Serum lipoprotiens Serum lipoprot...

Explain Serum lipoprotiens Serum lipoprotiens:- spherical  or  ellipsoidal  particles containing  proteins, cholesterol esters  and  triacylglycerols, encased  within  a mon

Define about the micro minerals, Define about the Micro Minerals? Micro...

Define about the Micro Minerals? Micro minerals are those minerals, which comprise less than 0.01% of the total body weight and are required in concentrations of one part per m

What are some things that have algae in them, What are some things that hav...

What are some things that have algae in them? Yeast is considered Algae.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd