Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Lymph, LYMPH - Lymph is a mobile connective tissue comprising lymph pla...

LYMPH - Lymph is a mobile connective tissue comprising lymph plasma (fluid) and lymphcorpuscles (cells).   COMPOSITIO N - (i )      Lymph Plasma - It is simil

How rb proteins phosphorylation affects the cell cycle, How Rb protein's ph...

How Rb protein's phosphorylation state affects the cell cycle and cancer progression. please put link or citation of where you find information.

Explain the history of plant classification, Explain the History of Plant C...

Explain the History of Plant Classification? Before Darwin's theory of evolution and publication of his epoch making work 'Origin of Species' in 1959 no outstanding basis for

What is represented by the cellular secretion, Q. What is represented by th...

Q. What is represented by the cellular secretion? Cell secretion is the removal to the exterior of substances produced by the cell for instance, hormones, mucus, and sweat, so

Explain the most probable number (mpn), Explain the Most Probable Number (M...

Explain the Most Probable Number (MPN)? MPN is a statistical estimating technique which is based on the fact that more the number of bacteria in a sample, more is the dilution

Explain nutritional requirements of microbes, Explain Nutritional Requireme...

Explain Nutritional Requirements of Microbes? Microorganisms require various nutrients and physical factors for their existence and growth. Nutrients are substances used in bio

Explain taxonomy - modern trends in animal taxonomy, Explain Taxonomy - Mod...

Explain Taxonomy - Modern Trends in Animal Taxonomy The term taxonomy which is derived from the Greek word 'taxis', meaning order or arrangement and nbmos ' meaning law, deals

Ground water sources and characteristics, After glaciers, ice caps and snow...

After glaciers, ice caps and snowfields, ground water is the next largest fresh water reservoir. Precipitation that does not evaporate back into the air and does not run off over t

What phenotypic ratios of the diploid, A wild-type strain of haploid yeast ...

A wild-type strain of haploid yeast is crossed to a mutant haploid strain to make a diploid. What phenotypic ratios will be observed in the haploid progeny of the diploid?

Show biological diversity is meiosis or mitosis, Q. For the biological dive...

Q. For the biological diversity is meiosis or mitosis the more important process? Meiosis is the cell division process that allows the formation of gametes to sexual reproducti

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd