Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

What determines an individual''s work capacity, What determines an individu...

What determines an individual's Work Capacity or VO 2 Max? Both aerobic and anaerobic mechanisms determine an individual's performance capacity. VO 2 max is determined by the

Zoochory - dispersal of seeds, Zoochory - Dispersal of Seeds Some frui...

Zoochory - Dispersal of Seeds Some fruits are eaten by animals and the seeds are passed out with the excreta (endozoochory). Plums, Lantana, grapes, figs and guava are example

What is community and workplace interventions, Q. What is Community and Wor...

Q. What is Community and Workplace Interventions? Community Based Interventions Involves health education regarding benefits of physical activities, dietary changes, includi

Evolution, what is r and k selection

what is r and k selection

Difference between ectoparasite and endoparasite, What is the difference be...

What is the difference between ectoparasite and endoparasite? Ectoparasites are parasites that explore the external surface of the host (as, for example, mites that parasite th

What is autophagic intracellular digestion?, Autophagic intracellular diges...

Autophagic intracellular digestion is the cellular internal digestion of waste and residual materials. In general it is completed by lysosomes. Autophagic intracellular digestio

Define the functionality of cellulose, Functionality of cellulose Cellu...

Functionality of cellulose Cellulose has many uses as an anticaking agent, emulsifier, stabilizer, dispersing agent, thickener and gelling agent, but these are generally subsid

Explain phylum tracheophyta, Phylum Tracheophyta Tracheophytes mean vas...

Phylum Tracheophyta Tracheophytes mean vascular plants. Tracheophyta includes ferns, the gymnosperms and the flowering plants. They have appeared some 400 million years ago, an

Biotic potential of a bacterial population, Q. How different is the growth ...

Q. How different is the growth according to the biotic potential of a viral population from the growth according to the biotic potential of a bacterial population? The growth c

Fats are essential for meeting nutritional need of essential, Why Fats are ...

Why Fats are essential for meeting nutritional need of essential? Fats are essential for meeting nutritional needs of essential, fatty acids like linoleic acid (n-6) and alpha

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd