Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Circulation - initiation of cpr, Circulation: If central pulses (femor...

Circulation: If central pulses (femoral  in infants and  carotid in  children) are not  palpable, begin chest compression without losing any time.  In  young infants, encircle

Food, FOOD Food consists of H O, minerals, vitamins carbohydrate, li...

FOOD Food consists of H O, minerals, vitamins carbohydrate, lipid & protein. A person needs 1600 cal. per day. This is BMR (Basal metabolic rate). Needed 2500 cal. per

Do all molecules of dna have the same amounts, Q. Do all molecules of DNA h...

Q. Do all molecules of DNA have the same amounts of nitrogenous bases? Number and sequence of nitrogenous bases in DNA molecule are key elements in variations which are found i

Reduction in the birth rate, State three conditions in a society which coul...

State three conditions in a society which could contribute to a reduction in the birth rate. Birth rate might be decreased by (i) later marriages (as smaller families), (

Water, Water Water usually forms about 50% to90% part of living protopl...

Water Water usually forms about 50% to90% part of living protoplasm. Life upon earth originated in the ocean and the conditions of that aqueous primeval environment have been r

What do you mean by monographs, Q. What do you mean by Monographs? A mo...

Q. What do you mean by Monographs? A monograph is defined as "the complete account as can be made at a given time of any one family, tribe or genus, nothing being neglected of

Personnel - neonatal care unit, PERSONNEL It is important that while a...

PERSONNEL It is important that while allocating nursing, medical and paramedical staffs, the needs of the neonatal unit should not be ignored. The highest priority in the orga

Do sea urchins have teeth, Do sea urchins have teeth? Sea urchins have ...

Do sea urchins have teeth? Sea urchins have a teeth-like structure juxtaposed to the mouth and made of five teeth linked to ossicles and muscle fibers. This structure, called a

Basic properties to proteins, Define Basic Properties To Proteins, To Be a ...

Define Basic Properties To Proteins, To Be a Good Foaming Agent? A protein must: a) Be able to rapidly absorb at the air-water interface during whipping, b) Undergo rapid

Define working of kidney in excretion of zinc in humans, Define working of ...

Define working of Kidney in excretion of zinc in humans? Very small amount of zinc is excreted in the urine (0.3-0.7 mg/day), as most of the zinc filtered by the kidney is reab

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd