Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Ventricular septal defect might be cyanotic, A newborn baby with a patent f...

A newborn baby with a patent foramen ovale or a ventricular septal defect might be cyanotic (blue). Will a two-year-old with these defects also be cyanotic? Explain your answer.

Define reagents for preparation of phosphate buffers, Define Reagents for P...

Define Reagents for Preparation of Phosphate Buffers? Buffer solutions of pH4, pH7 and pH 9.18 phosphate buffer solution: 0.1 M disodium hydrogen phosphate or Na 2 HPO 4

Individuals with tyrosinenmia, Individuals with tyrosinenmia have food patt...

Individuals with tyrosinenmia have food patterns very similar to the one for PKU discussed above. PKU is more common than tyrosinemia. Foods that are high in tyrosine and phenylala

Are microorganisms directly or indirectly affects our lives, Describe 5 way...

Describe 5 ways that a microorganisms directly or indirectly affects our lives.

Fibroblast, Fibroblast  is the term applied to a cell of connective tissue ...

Fibroblast  is the term applied to a cell of connective tissue which is separated from similar cells by some degree of the matrix material; fibroblasts secrete elastin and collagen

Colibacillosis of poultry, Colibacillosis of poultry Colibacillosis is...

Colibacillosis of poultry Colibacillosis is an important disease among poultry, especially among broiler chicks aged 6-9 weeks and less frequently of young chicks during first

A light microscope with unlimited resolution, Theoretically you can build a...

Theoretically you can build a light microscope with unlimited magnification, but can you build a light microscope with unlimited resolution? Why or why not? (Hint: what really cont

Physiological & socio psychological factor- public nutrition, Define Physio...

Define Physiological and Socio Psychological Factors - public nutrition? Food related behaviour depends on a combination of biochemical factors, mainly, physiological aspects a

What is the typical feature of the epithelia, What is the typical feature o...

What is the typical feature of the epithelia? How different is it from the connective tissue? The typical feature of the epithelium is the absence or almost absence of space a

Working glucagon and insulin for the blood glucose control, Q. What are the...

Q. What are the functions of glucagon and insulin for the blood glucose control? Glucagon increases insulin and glycemia reduces it. They are antagonistic pancreatic hormones.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd