Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Non-striated or smooth muscles, NONSTRIATED (= SMOOTH) MUSCLES - Non...

NONSTRIATED (= SMOOTH) MUSCLES - Non-striated muscles are found in the posterior part of oesophagus, stomach, intestine, lungs, urinogenital tract, urinary bladder, blood ve

Hormones secreted by thyroid gland, Hormone s . The thyroid gland secretes...

Hormone s . The thyroid gland secretes following hormones. Thyroxine (tetraiodothyronine or T 4 )' and tri-iodothyronine or T 3 are secreted by the thyroid follicular cells.

Data gathering - steps in nursing process, Data Gathering   It is the g...

Data Gathering   It is the gathering of information about client's physical heath, mental outlook, social circumstances, family and community life, and other factors. To p

Explain tropical rain forests in biomes, Explain Tropical Rain Forests in b...

Explain Tropical Rain Forests in biomes? You probably are well aware of the danger that the world's rain forests are facing in terms of extinction! There are huge numbers of sp

Welfare, what is welfare in biology

what is welfare in biology

How can the hemolytic disease of the newborn be prevented, How can the hemo...

How can the hemolytic disease of the newborn be prevented? The Erythroblastosis fetalis can be prevented if in the first delivery of a Rh+ child from a Rh- mother serum contain

Do the membranes form only the outer wrapping of cells, Q. Do the membranes...

Q. Do the membranes form only the outer wrapping of cells? Lipid membranes do not form only the outer cover of cells. Cell organelles, such as the Golgi complex, lysosomes, chl

Define ziehl-neelsen staining technique, Define Ziehl-Neelsen Staining Tech...

Define Ziehl-Neelsen Staining Technique? Ziehl-Neelsen staining is used for staining these bacteria. The technique was discovered first by Robert Koch during his pioneering inv

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd