Renin-angiotensin system, Biology

Assignment Help:

As heart failure sets in, there is activation of RAS (Fig 2.1). Adrenergic stimulation of beta-1 receptors in juxtaglomerular apparatus of the kidneys results in release of renin. Another mechanism i.e. responsible for renin release is baroreceptor stimulation in renal vascular bed by reduction of renal blood flow.  

Angiotensin II that is released is a powerful vasoconstrictor and stimulates the release of aldosterone. It also causes remodeling of cardiac myocytes. Aldosterone retains sodium and has direct effects on myocardium. The result is increased systemic vascular resistance and development of edema. Hence the interruption of this renin-angiotensin-aldosterone axis by angiotensin-converting enzyme inhibitors (ACE-Inhibitors) or angiotensin receptor blockers (ARBs) has salutary effects as there is reduction in systemic vascular resistance, afterload reduction, mild diuresis and improvement in the cardiac output.

Angiotensin II also has direct role in modifying the structure and function of myocardium.

2243_Renin-Angiotensin System.png


Related Discussions:- Renin-angiotensin system

#organisation of the human bodytitle.., dhow is the structure of connective...

dhow is the structure of connective tisse linked to their function

Hemorrhagic enteritis, H e morrhagic enteritis in Turkeys The viral e...

H e morrhagic enteritis in Turkeys The viral etiology in turkey poults showing sudden death was first described in1930 and thereafter reported in most turkey-producing areas.

Tuberculosis, Tuberculosis Tuberculosis is caused by a Bacillus-myco...

Tuberculosis Tuberculosis is caused by a Bacillus-mycobacterium tuberculosis, a gram- positive and acid-fast organism. It is communicable disease. Mode of Transmissio

Determine the food sources of fluoride, Determine the Food Sources of Fluor...

Determine the Food Sources of Fluoride? The major source of fluoride in most diets is water, with foods providing only about 25% of total intake. These include tea and marine f

What are the tupes of aortic aneurysm surgery, What are the tupes of Aortic...

What are the tupes of Aortic Aneurysm Surgery? Types of Surgery :  Technique of surgery and the approach depends on the site of thoracic or thoraco abdominal aortic aneuiysm.

Types of mental disorder, TYPES OF MENTAL DISORDER - 1 .       Psycho...

TYPES OF MENTAL DISORDER - 1 .       Psychosis 2 .       Neurosis 3.       Personality & character disorders 1 .       PSYCHOSIS - It effects mental capa

Relation between the hypophysis and the thyroid, Q. What is the relation be...

Q. What is the relation between the hypophysis and the thyroid? The hypophysis secretes TSH (thyroid- stimulating hormone). This hormone hastens the secretion of thyroid hormon

Blood be enhanced during vigorous activity, The percentage of oxygen absorb...

The percentage of oxygen absorbed from the air in the lungs is always about the similar, so how can the oxygen supply to the blood be enhanced during vigorous activity? Breathi

Illustrate homologous chromosomes, Q. In which period of meiosis does the p...

Q. In which period of meiosis does the pairing of homologous chromosomes occur? The pairing of homologous chromosomes is a very important step for meiosis because the rightness

What are synthetic auxins, What are synthetic auxins and what are their use...

What are synthetic auxins and what are their uses? Synthetic auxins, like indolebutyric acid (IBA) and naphthalenic acid (NAA) are substances same to IAA (a natural auxin) but

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd