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Quality-adjusted survival analysis is a method for evaluating the effects of treatment on survival which allows the consideration of quality of life as well as the quantity of life. For instance, a highly toxic treatment with number of side effects might delay disease recurrence and increase the survival relative to a less toxic treatment. In this type of situation, the trade-off between negative quality-of-life impact and positive quantity-of-life impact of the more toxic therapy should be evaluated when determining which treatment is most probable to advantage a patient. The method precedes by defining the quality function which assigns a 'score' to the patient which is a composite measure of quality and quantity of life both. In common the quality function assigns a small value to the short life with poor quality and high value to the long life with good quality. The assigned scores are then taken in use to calculate quality- adjusted survival times for the analysis.
1) Let N1(t) and N2(t) be independent Poisson processes with rates, ?1 and ?2, respectively. Let N (t) = N1(t) + N2(t). a) What is the distribution of the time till the next epoch
Mean squarederror is the expected value of square of the difference between an estimator and the true value of the parameter. If the estimator is unbiased then the mean of the squ
The growth in bad debt expense for Johnston office supply Company over this time period.If this rate continues,estimate the percentage increase in bad debts for 1997,relative to 19
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Write a c++ program to find the sum of 0.123 ? 103 and 0.456 ? 102 and write the result in three significant digits
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