Pyruvate carboxylase activation, Biology

Assignment Help:

Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function.  Intended for the latter reason the  activity  of  pyruvate  carboxylase   depends  absolutely  on  the  presence  of acetyl  CoA; the biotin  prosthetic  set  of the enzyme  cannot  be carboxylated unless acetyl  CoA is bound  to the enzyme.  This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.

 


Related Discussions:- Pyruvate carboxylase activation

Nutritional management for lactose intolerance, Q. Nutritional Management f...

Q. Nutritional Management for lactose intolerance? Diagnostic tests are available that can give information about the level and activity of the lactase enzyme. Depending on the

What do you mean by hansens disease, Q. What is Hansen's disease (etiologic...

Q. What is Hansen's disease (etiological agent, mode of transmission, clinical manifestations and prevention)? The etiological agent of the Hansen's disease is bacteria called

What is the significance of pharyngeal gill slit, What is the significance ...

What is the significance of Pharyngeal gill slit ? Lateral opening in the wall of the pharynx which allows water to enter into the mouth and exit through the pharynx. This is on

Protozoa, advantages and disadvantages of protozoa

advantages and disadvantages of protozoa

What are the types of digestion, What are the types of digestion and of dig...

What are the types of digestion and of digestive system of platyhelminthes? Flatworms have incomplete digestive systems and they show intracellular and extracellular complement

What is the reason for the low red blood cell count, A patient has a low re...

A patient has a low red blood cell count, and microscopic examination reveals an abnormally high proportion of circulating reticulocytes. Upon subsequent examination, the patient i

Financial accounting software, Financial Accounting Software An Ide...

Financial Accounting Software An Ideal Accounting Software should have the following features:  Purchase Details  Invoice Details  Purchase/Sale Return (Debit/Cre

Determine requirement of carbohydrate for endurance events, Determine the R...

Determine the Requirement of carbohydrate for Endurance Events? For endurance events like sprinting (100 m run), football, hockey, the carbohydrate intake can be placed at 7:10

The skeletal system, Where does cartilage occur in a joint and what is its ...

Where does cartilage occur in a joint and what is its function ?

Different types of stems, Different types of stems (a)  Monocots. Secur...

Different types of stems (a)  Monocots. Secure stems of various plants such as bamboo, sugar cane and corn. Cut every of the stems crosswise with a very sharp knife or razor bl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd