Pyruvate carboxylase activation, Biology

Assignment Help:

Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function.  Intended for the latter reason the  activity  of  pyruvate  carboxylase   depends  absolutely  on  the  presence  of acetyl  CoA; the biotin  prosthetic  set  of the enzyme  cannot  be carboxylated unless acetyl  CoA is bound  to the enzyme.  This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.

 


Related Discussions:- Pyruvate carboxylase activation

What are the main harms caused by vitamin a deficiency, What are the main h...

What are the main harms caused by vitamin A deficiency? How does this vitamin act in the physiology of vision? Deficiency of vitamin A (retinol) might be cause night blindness

Do the membranes form only the outer wrapping of cells, Q. Do the membranes...

Q. Do the membranes form only the outer wrapping of cells? Lipid membranes do not form only the outer cover of cells. Cell organelles, such as the Golgi complex, lysosomes, chl

Depth and currents, Depth and Currents Depth The sea is v...

Depth and Currents Depth The sea is very deep varying in different regions. Generally life extends to all depths but is confined more to the continental shelf and

Explain sertoli cells, Sertoli cells are found in: 1. ovaries and secre...

Sertoli cells are found in: 1. ovaries and secrete progesterone 2. adrenal cortex and secrete adrenaline 3. seminiferous tubules and provide nutrition to germ cells 4.

Neurons, how does sodium and potassium ions maintain the resting petential ...

how does sodium and potassium ions maintain the resting petential of neurons

Explain animal fats, Animal Fats This group consists of depot fats from...

Animal Fats This group consists of depot fats from domestic land animals (e.g., lard and tallow), all containing large amounts of C16 and C18 fatty acids, medium amounts of uns

External factor - factor controlling metamorphosis in insect, External fact...

External factors - Factors Controlling Metamorphosis in Insects In few cases an external factor may be accountable for initiating moulting, as for instance in the blood su

Define methods for determining ph - nutritional biochemistry, Define Method...

Define Methods for determining pH? There are two general methods for determining pH of a solution. One is the colorimetric method and the other most common method is the use of

What is an immunotoxin, Immunotoxin is formed by conjugating or combining a...

Immunotoxin is formed by conjugating or combining an antibody with highly toxic agent.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd