Pyruvate carboxylase activation, Biology

Assignment Help:

Oxaloacetate has two main roles. It is an intermediate which is consumed in gluconeogenesis and it is also a key intermediate in the citric acid cycle where it fuses with acetyl CoA to form citrate, finally being regenerated by the cycle. Thus pyruvate carboxylase produces oxaloacetate for gluconeogenesis but also must maintain oxaloacetate stages for citric acid cycle function.  Intended for the latter reason the  activity  of  pyruvate  carboxylase   depends  absolutely  on  the  presence  of acetyl  CoA; the biotin  prosthetic  set  of the enzyme  cannot  be carboxylated unless acetyl  CoA is bound  to the enzyme.  This allosteric activation by acetyl CoA ensures which more oxaloacetate is made when excess acetyl CoA is available. In this role of maintaining the level of citric acid cycle intermediates and the pyruvate carboxylase reaction is learn to be anaplerotic which is filling up.

 


Related Discussions:- Pyruvate carboxylase activation

Dilute this concentration of cells to yield 300 cells, For a particular ass...

For a particular assay, you require cells at a concentration of 300 cells per ml. In your flask of cells growing you counted a sample using a hemacytometer and found that you have

Skin., what are the main functions of basal (Malpighian)layer?

what are the main functions of basal (Malpighian)layer?

Eye and ear examination of new born, Eyes Check for conjuctivitis, epi...

Eyes Check for conjuctivitis, epicanthal folds, and observe the inner canthus of both eyes. Look for squint, nystagmus, trauma, lacrimal duct obstruction, corneal opacity, c

Hypoglycemic effects of dietary factor, Define Hypoglycemic effects of Diet...

Define Hypoglycemic effects of Dietary Factor with antinutritional effect? Of the different carbohydrate foods tested for starch digestibility and blood glucose response, those

Natural disasters, EARTHQUAKES          An earthquake with its terrible...

EARTHQUAKES          An earthquake with its terrible aftereffects is one of the most frightening and destructive phenomena of nature. It can be defined as a sudden movement of

Define interaction of vitamin c with other vitamins, Define Interaction of ...

Define Interaction of Vitamin C with other vitamins? a. Ascorbic acid and other vitamins: Ascorbic acid synthesis is diminished in thiamin and riboflavin deficiency. Vitamin

Procedure for preparation of selective & differential medium, Procedure for...

Procedure for Preparation of Selective and Differential Medium Now prepare the MacConkey agar medium following the steps given herewith: 1. Weigh and dissolve all ingredient

Why phylogenies using maximum likelihood methods, When constructing phyloge...

When constructing phylogenies using maximum likelihood methods, you assume?

How substrate concentration affect the enzymatic reaction, How does the sub...

How does the substrate concentration affect the speed of enzymatic reactions? Initially as substrate concentration increases, the speed of the reaction enhances; this happens b

What is the production of the rna, Q. What is the production of the RNA cal...

Q. What is the production of the RNA called and what is the enzyme that catalyzes the procedure? The making of the RNA from information contained in the DNA is called transcrip

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd