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Protopathic bias is the type of bias (also called as reverse-causality) that is a consequence of differential misclassification of the exposure related to timing of occurrence. It occurs when a change in exposure taking place in the time following disease occurrence is the incorrectly thought to precede disease occurrence. For instance, a ?nding that alcohol has a protective effect for the clinical gallstone disease may be explained by the reduction in alcohol use because of the symptoms related to gallstone disease.
This term is sometimes used for the data collected in those longitudinal studies in which more than the single response variable is recorded for each subject on each occasion. For
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Omitted covariates is a term generally found in the connection with regression modelling, where the model has been incompletely specified by not including significant covariates.
Play-the-winner rule is a process sometimes considered in the clinical trials in which the response to treatment is positive (a success) or negative (a failure). One of two treatm
Mendelian randomization is the term applied to the random assortment of alleles at the time of gamete formation, a process which results in the population distributions of genetic
This term applied in the context of comparing the different methods and techniques of estimating the same parameter; the estimate with the lowest variance being regarded as the mos
Chernoff's faces : A method or technique for representing the multivariate data graphically. Each observation is represented by the computer-created face, the features of which are
Multicentre study : The clinical trial conducted simultaneously in the number of participating hospitals, with all centres following an agreed-upon study of the protocol and with
The transformation of the Pearson's product moment correlation coefficient, r, can be given by The statistic z has the normal distribution with mean here ρ is the pop
Quota sample is the sample in which the units are not selected at the random, but in terms of a particular number of units in each of a number of categories; for instance, 10 men
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