Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Literature review on co2 positive displacement pump, How can I get the lit...

How can I get the literature review on fabrication and construction of a modified Co2 single stroke positive displacement pump driven with electric motor

Hermite curve, A hermite curve passes through the points (1,0), (0.866, 0.5...

A hermite curve passes through the points (1,0), (0.866, 0.5), (0.5, 0.866), (0,1) which are parameterized at u=0,0.25,0.75,1 respectively. determine geometric coefficient of the c

Btec, advantages and disadvantages of kanban

advantages and disadvantages of kanban

Engine, What is ignition angle offset

What is ignition angle offset

Control system, hi i have an assignment in control system can u do it ?

hi i have an assignment in control system can u do it ?

Array, sorting order of arra

sorting order of arra

#flow rate in turbochargers, What is the amount of air is supplied to engin...

What is the amount of air is supplied to engine via turbochargers and how their sizes vary from engine to engine ?

Evaluate the absolute velocity of jet, A jet of water moving at 8 m/sec. im...

A jet of water moving at 8 m/sec. impinges on a concave-shaped vane to deflect the jet through 120 o when stationary. If the vane is moving at 5 m/sec., calculate the angle of jet

Find the maximum permissible, A wooden cylinder (specific gravity = 0.6) of...

A wooden cylinder (specific gravity = 0.6) of circular cross - section having length L and diameter D floats in water. Find the maximum permissible (L/D) ratio so that the cylinder

Plant maintenance, which book is prefferable for plant maintenance?

which book is prefferable for plant maintenance?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd