Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Co2 gas supply-co2 welding, CO 2 Gas Supply The CO 2 shielding gas is...

CO 2 Gas Supply The CO 2 shielding gas is supplied cylinders at high pressure (140 kg / cm 2 ). Therefore pressure regulator and flow meter are connected to reduce the pressu

EM2013KEN2401MECH, Hi. I have made a payment for the above ticket number. W...

Hi. I have made a payment for the above ticket number. Will I get all the workings out too? [email protected]

Loosening a part with multiple fasteners services tips, Loosening a Part wi...

Loosening a Part with Multiple Fasteners: Loosening a part with multiple fasteners should be done from the outside to inside in a criss-cross pattern, loosening the small fastener

What is drilling machine, What is drilling machine The machine used for...

What is drilling machine The machine used for drilling is called drilling machine. The drilling operation can also be accomplished in lathe, in which the drill is held in ta

Solved numarical, The following observations were made during a tensile tes...

The following observations were made during a tensile test on mild steel specimen 60 mm in diameter and X mm long. Elongation with 50 KN load (within the limit of proportionality)

Cases of equilibrium , Cases of equilibrium: What are cases of equili...

Cases of equilibrium: What are cases of equilibrium? Sol.: As a result of the acting forces, the body may be having one of the following states: (1) The body can mo

Show hazards associated with plants, Q. Show Hazards associated with plants...

Q. Show Hazards associated with plants? Hazards associated with plants will typically include the following: • Inherent fire hazards presented by the release of flammable g

Cnc lathe job clamping system, can we use electrical power chuck for job cl...

can we use electrical power chuck for job clamping in cnc lathe.what are the issues related

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd