Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

What is epoxy powder, Q. What is Epoxy Powder? The coating manufacturer...

Q. What is Epoxy Powder? The coating manufacturer shall be consulted as to the product best suited to the Applicator's speed of coating, pipe diameter and wall thickness, and t

Thermal Stresses in Tapered Section, A rigidly fixed circular bar 1.75mm lo...

A rigidly fixed circular bar 1.75mm long uniformly tapers from 125mm dia. at 1 end to 100mm dia. at other end. If the max. stress in the bar is not to exceed 108MPa. Find the tempe

Evaluate thermal efficiency of the engine, A carnot engines performs betwee...

A carnot engines performs between two reservoirs whose difference in temperature is 200 o C. If the work output of the engine is 0.5 times the heat rejected, make evaluation for th

Spot welding of different metals, Spot welding of different metals Thou...

Spot welding of different metals Though, mild steel is t he metal most commonly used, any prime metal or alloy can be successfully spot welded provided that machine with suitab

Inertia -factors in clutch design , Inertia : The clutch rotating part sho...

Inertia : The clutch rotating part should have minimum inertia. Otherwise, when the clutch is released for gear changing, the clutch plate will keep on spinning, causing hard shif

Statics, what are the applications of statics in engineering

what are the applications of statics in engineering

Metals and melting practices - ladle, Metals and Melting Practices - Ladle,...

Metals and Melting Practices - Ladle, Limestone,Ore,Sinter Ladle : A big bucket utilized as a carrier for molten metal. Limestone : A Blast Furnace raw material that elimi

Assignment, AskTask 2 (3 questions) Material engineers should be conversant...

AskTask 2 (3 questions) Material engineers should be conversant of various materials, their properties, manufacturing process involved, environmental issues, monetary issues and mo

Determine the thermal conductivity, A rod of 80mm diameter and 10mm length ...

A rod of 80mm diameter and 10mm length with thermal conductivity 16W/m-deg protrudes from a surface at 160 o C. The rod is exposed to air at 30 o C with convective coefficient of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd