Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

What do you mean by compression moulding, Q. What do you mean by Compressio...

Q. What do you mean by Compression moulding? In compression molding, a material normally in power or perform shape , is loaded directly into the hot die cavity, pressure from

Lifting machines, Lifting machines: Basic definitions of the lifting m...

Lifting machines: Basic definitions of the lifting machines and some lifting machines have been described. For each of these machines, derivation of the formulae for mechanica

Evaluate the specific enthalpy - thermodynamics, Evaluate the specific enth...

Evaluate the specific enthalpy - thermodynamics: Steam is being generated in a boiler at a pressure of 15.25 bar. Calculate the specific enthalpy when ( i )  Steam i

Two position synthesis, Two position synthesis of crank rocker mechanisms

Two position synthesis of crank rocker mechanisms

Predictive control algorithms, Predictive Control Algorithms Escaping S...

Predictive Control Algorithms Escaping Scheduling Errors via Partial Look-ahead Since previously mentioned above, the heuristic priority rules that are normally utilized in

Describe root-finding techniques, In mechanics, stress is a measure of the ...

In mechanics, stress is a measure of the internal forces acting within a deformable body. Quantitatively, it is a measure of the average force per unit area of a surface within the

Welding, pre heating of casted material for welding

pre heating of casted material for welding

Write down the uses of vernier caliper and steel rule tools, Write down the...

Write down the uses of following tools and make neat sketches of the same : (a) Vernier Caliper (b) Steel Rule

Structures of materials, what is the difference between atomic structure an...

what is the difference between atomic structure and crystal structure

Subsea Valves, Read two documents that will provide and answer the followin...

Read two documents that will provide and answer the following questions: 1) You will note from reading the above referenced specifications that fewer valve types are recommended fo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd