Original hodgkin-huxley model, Mechanical Engineering

Assignment Help:

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?


Related Discussions:- Original hodgkin-huxley model

Explain the process for using the two small pipes, Method:- Using the two s...

Method:- Using the two small pipes - Radial Drilling machine First we make a base. Then we attach column to the base. Then show the table atmiddle of the column. Then after we

Radiative heat transfer, how to find view factor for a cylinder to humanbod...

how to find view factor for a cylinder to humanbody at a distance?

Arc welding power sources classify-output characterstics, ARC WELDING POWER...

ARC WELDING POWER SOURCES CLASSIFICATION:OUTPUT CHARACTERSTICS The output characteristic of welding power source is a funct ional relationship between output voltage and load

Impulse- momentum - work and energy, Impulse, Momentum, Work and Energy: ...

Impulse, Momentum, Work and Energy: As a part of summary, you can remember various important principles in terms of following equations.  (i)        Impulse-Momentum equati

Plate clutch movement on center clutch-clutch jerking, Plate clutch movemen...

Plate clutch movement on center clutch : Place plate clutch on centre clutch as shown in the picture and move the plate clutch up and down, while moving the plate clutch in the ce

Mechanics, definition of open and cross belt drive

definition of open and cross belt drive

Supports for rigid bodies - space structures, Supports for Rigid Bodies (Sp...

Supports for Rigid Bodies (Space Structures): The primary step in solving equilibrium problems is to draw free-body diagram. Isolate the body through its surrounding. Replace

Kinematics equations, Kinematics Equations Kinematics deals with problem...

Kinematics Equations Kinematics deals with problems involving distance, velocity, time and constant acceleration. The restraint that acceleration is a constant for these problem

Inspection of flange assembly, Q. Inspection of Flange assembly? Flange...

Q. Inspection of Flange assembly? Flanges shall be clean and free of old gasket fragments, scratches, burrs, pits, etc. if needed, the flange surfaces shall be cleaned with a s

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd