O-linked oligosaccharides , Biology

Assignment Help:

Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:

?   O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.

?   N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2   where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.

 


Related Discussions:- O-linked oligosaccharides

Multiplication phas - stages of spermatogenesis, Multiplication Phas - Stag...

Multiplication Phas - Stages of spermatogenesis The initial cells in the germ line arc known as primordial germ cells (PCC). The PGC, which arise at some distance from the pro

Describe circulatory system, Circulatory system:  One of the eleven major b...

Circulatory system:  One of the eleven major body organ systems in animals; carbon dioxide, nutrients, transports oxygen, and waste products between the cells and the respiratory s

What is the phenotype, What is the phenotype? Phenotype is every observ...

What is the phenotype? Phenotype is every observable characteristic of a living being conditioned by its genes. A few phenotypes may be altered by nongenetic factors (for insta

Define role of vitamin k in controlling gene expression, Define role of Vit...

Define role of Vitamin K in controlling gene expression? Prithrombin, a protein required for blood clotting is assembled with a large number of glutamic acid residues. In the p

How does phosphocreatine act in the muscle contraction, How does phosphocre...

How does phosphocreatine act in the muscle contraction and relaxation? Phosphocreatine is the main means of energy storage of the muscle cells. During relaxed periods ATP mo

Suger diabetes, what normally cause type one sugar diabetes

what normally cause type one sugar diabetes

What do you understand by exoskeleton, What do you understand by Exoskeleto...

What do you understand by Exoskeleton. Supporting structures of skeleton not surrounded by the body. Endoskeletal elements are secreted by an underlying epidermis and one side

Precautions for estimation of sucrose by fehling soxhlet, Explain Precautio...

Explain Precautions for Estimation of Sucrose by Fehling Soxhlet Method? 1. Maintain proper temperature of the water bath for complete hydrolysis. 2. Add distilled water to

Morphological changes - floral induction, Morphological Changes - Floral In...

Morphological Changes - Floral Induction Some of the morphological changes that accompany floral induction are: Change in the shape of meristem, Increase in the ra

Homozygous and weterozygous, Homozygous and Weterozygous In an individu...

Homozygous and Weterozygous In an individual two identical alleles may exist [or a given character and, hence, the individual is referred to as Homozygous (e.g. AA and aa). If

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd