O-linked oligosaccharides , Biology

Assignment Help:

Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:

?   O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.

?   N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2   where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.

 


Related Discussions:- O-linked oligosaccharides

What are the main techniques of genetic engineering, At the present level o...

At the present level of the biotechnology what are the main techniques of genetic engineering? The main methods of genetic engineering today are: the recombinant DNA technology

Explain about the saponins, Explain about the Saponins? These are a div...

Explain about the Saponins? These are a diverse group of compounds commonly found in legumes like soybean, lentils, chickpeas, peanuts and alfalfa sprouts. They are also presen

Periannular extension of infection, Occur in 10 per cent to 40 per cent of ...

Occur in 10 per cent to 40 per cent of all native-valve IE, and complicates aortic IE more commonly than mitral or tricuspid IE. Periannular infection is of even greater concern wi

What are flagella and cilia, Q. What are flagella and cilia and how do thes...

Q. What are flagella and cilia and how do these structures acquire movement? What are some examples of flagellated and ciliated cells in humans? Flagella and Cilia are structur

Why are grasshopper is said to show male heterogamity, a) Why are grasshopp...

a) Why are grasshopper and Drosophila said to show male heterogamity? Describe. b) Define female heterogamity with the help of an example.

What are plant hormones, What are plant hormones? Plant hormones, also ...

What are plant hormones? Plant hormones, also known as phytohormones, are substances that control the embryonic development and the growth of the adult plant.

Conjugation – protozoan, Conjugation – Protozoan Conjugation is charac...

Conjugation – Protozoan Conjugation is characteristic of ciliates. The details vary from species to species. The general features can be observed in Paramecium sps. which has

Vertebrates & invertebrates, Evolution of vertebrates and invertebrates ner...

Evolution of vertebrates and invertebrates nervous system

Define development - terminologies used in chromatography, Define Developme...

Define Development - Terminologies used in Chromatography? Development is the process of passing a mobile phase over the adsorbent or support. During the development the sample

Regulation of egg, difference between mosaic and regulation egg

difference between mosaic and regulation egg

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd