O-linked oligosaccharides , Biology

Assignment Help:

Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:

?   O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.

?   N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2   where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.

 


Related Discussions:- O-linked oligosaccharides

Define about the anthropometry method, Define about the Anthropometry Metho...

Define about the Anthropometry Method? Anthropometry refers to the measurement of the size and proportions of' the human body. Anthropometric prediction equations estimate body

Bovine spongiform encephalopathy (bse), B o vi n e spongiform encephalo...

B o vi n e spongiform encephalopathy (BSE) Bovine spongiform encephalopathy (BSE) is a transmissible, neurodegenerative, fatal brain disease of cattle characterized by post

Infective endocarditis, Infective Endocarditis It is an infection of...

Infective Endocarditis It is an infection of the endocardial surface with micro organisms present in the lesion. The endocardium is contagions with the valves of the heart.

What possible combinations of chromosomes will be present, A diploid cell c...

A diploid cell contains three pairs of homologous chromosomes designated C1 and C2, M1 and M2, and S1 and S2; no crossing over occurs. What possible combinations of chromosomes

What are the grain boundaries, What are the Grain boundaries Grain boun...

What are the Grain boundaries Grain boundaries disrupt the motion of dislocations by a material, so reducing crystallite size is a common way to improve strength. Since grain b

Accuracy of stress echocardiography, Q. Define Accuracy of Stress Echocardi...

Q. Define Accuracy of Stress Echocardiography? The accuracy of stress echo tests for the detection of coronary artery disease is expressed as the sensitivity and specificity of

Components of ecosystem, An ecosystem consists of two types of components: ...

An ecosystem consists of two types of components: (a)   Abiotic components: This includes the non-living components of the ecosystem. These are physical and chemical fact

Explain about the canning of food, Explain about the Canning of Food? Y...

Explain about the Canning of Food? You must have seen the markets flooded with canned products. Can you name a few of such products? Yes the canned juices, canned aerated drink

Inotropic agents, All currently available inotropic agents act to increase ...

All currently available inotropic agents act to increase Ca 2+ for activation in both normal and failing myocardium (Hurst). The use of inotropic agents in the treatment of CHF is

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd