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Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:
? O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.
? N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2 where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.
Sheep-pox Sheep-pox, a highly contagious disease, causes a mortality of 20 to 50% in animals below the age of 6 months. It also causes damage to the wool and skin in adults. Of
DNA fingerprinting produces a unique banding pattern of DNA fragments for comparison with other DNA samples.
Prevention of malaria No drug for malaria prevention is 100% effective. Travelers to countries that have malaria should seek prompt medical attention for febrile illness wherea
For patients with end-stage heart failure, cardiac transplantation has become a promising therapy especially with the advent of immunosuppressive therapy and more careful screenin
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What is Neurophysics Neurophysics is the field of biophysics dealing with nervous system. Neurophysics covers a extensive spectrum of phenomena from molecular & cellular mechan
Does an increase of H+ cause the hemaglobin oxygen binding curve to shift to the left or right? Explain.
Q. Dietary Management for ulcerative colitis? Proper dietary management is important for maintaining a good nutritional status of the patient. Long-term management is generally
The Physical Environment The actual hospital environment is another factor that may be stressful for the child and family. There are many unfamiliar sights, sounds and smells
I nfectious coryza A highly infectious bacterial disease of chickens caused by Hemop hilus paragallinarum, is characterized by catarrhal inflammation of the upper respirator
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