O-linked oligosaccharides , Biology

Assignment Help:

Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:

?   O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.

?   N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2   where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.

 


Related Discussions:- O-linked oligosaccharides

How does epistasis affect proportion of phenotypical form, In the hybridiza...

In the hybridization of 2 genes (4 different alleles, 2 of each pair) how does epistasis affect the proportion of phenotypical forms in the F2 generation? In the dihybridism wi

Viral vectors, Viral vectors   There are a large number of viral vector...

Viral vectors   There are a large number of viral vectors available which can transfer the desired sequence properly into the host. Examples of the viral vectors are as follows

Extraradicular infections, Extraradicular Infections Whatever the cause...

Extraradicular Infections Whatever the cause of post endodontic disease we should do proper diagnosis to determine what is the cause; is it intra or extraradicular infection ,

Explain coelomates, Explain Coelomates? Recall that Acoelomates have so...

Explain Coelomates? Recall that Acoelomates have solid bodies, and Pseudocoelomates have body cavities that form between the endoderm and the mesoderm. In contrast, the body ca

Determine in brief about the mse, Determine in brief about the MSE The ...

Determine in brief about the MSE The MSE deals with questions concerning the addressee's Consciousness, Emotional State, Thought Content and Clarity, Memory, Sensory Perception

Cranial nerves, The cranial nerves are composed of twelve pairs of nerves...

The cranial nerves are composed of twelve pairs of nerves which emanate from the nervous tissue of brain. In order to reach their targets they should ultimately exit/enter the cr

Explain unresorbable barriers - root perforation, Explain Unresorbable Barr...

Explain Unresorbable Barriers - Root Perforation MTA exhabits excellent tissue biocompatible non resorbable barrier and restorative material. It represents an extraord

Explain functional property of emulsification, Explain Functional property ...

Explain Functional property of Emulsification Mode of action  Proteins stabilize fat emulsions Food system Sausages, soups, cakes, salad dressings, infant foods

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd