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Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:
? O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.
? N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2 where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.
Extra Cranial MAs Intrathoracic or intra-abdominal MAs are often asymptomatic until leakage or rupture occurs. Most extracranial MAs (ECMAs) will rupture if not excised. The app
When the chromosomes are depleted of histones they are seem to have a central fibrous 'protein scaffold' or nuclear matrix to which the DNA is attached in loops. Therefo
Phosphorus cycle is sedimentary cycle because it does not enter into atmosphere. It can be found on earth in water, soil and sediments. The phosphorus cycle is the biogeochemical c
Explain the Treatment of iron deficiency anaemia? Oral iron is the preferred method of treatment of IDA. The dosage is decided depending on the severity of the condition. Gener
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A decrease in blood plasma levels of parathyroid hormone A. occurs in response to an increase in the levels of calcium ions in blood plasma. B. leads to an increase in the a
Estimation of Nitrogen and Protein Content Using Micro Kjeldahl's Method? Standardization of H 2 SO 4 Prepare a solution of 0.1 N H 2 SO 4 by diluting 2.8 ml of the con
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The several types of steam sterilizers that are in use. 1. Lab Autoclave 2. Hospital dressing sterilizer 3. Bowl & instrument sterilizer 4. Rapid cooling sterilizer
A lot of hemodynamic information including maximum and mean velocity, maximum and mean pressure gradients and pressure half time can be obtained from Doppler trace that helps in
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