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NON-PROTEIN AMINO ACIDS
Non-protein amino acids are the ones which are not incorporated in proteins but occur freely or in combined state in non-protein substances.
Their number is more than 180.
(i) Ornithine and Citrulline threonine.
(ii) Homoserine is intermediate in synthesis of cysteine, methionine and threonine.
(iii) Diaminopimelic acid is intermediate in synthesis of lysines.
(iv) D-Alanine and D-Glutamic acid are component of peptidolycan of bacterial wall.
(v) Gamma Aminobutyric acid or GABA is a synaptic neurotransmitter that causes inhibition by opening chloride channels.
(vi) A number of antibiotics contain amino acid analogues that prevent protein synthesis, e.g., D-Phenylalanine in Gramicidin - S
(vii) Actinomycin - D, an inhibitor of RNA synthesis, contains D-Valine.
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What would be the approximate number of amino acids of a protein with a mass of 203 kd? Assume an average molecular weight for amino acids of 110 grams/mol.
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