Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Molecular Response to Thyroid Hormones during Metamorphosis
Thyroid hormones can cause obtainable tissues to break down or can remold the tissues to their adult function. The liver cells of the tadpole for instance are not destroyed and replaced during metamorphosis. In place of their structure is remodeled. This change is accompanied by dramatic raise in ribosomal and messenger RNA synthesis. The rate of protein synthesis also increases nearly 100 folds in four hours of thyroid hormone stimulation. Many of the new mRNAs are those that code for new functions of the liver. The main increase in protein synthesis appears to come from the transcription of new m-RNAs.
Carbamoylphosphate synthase (a urea cycle enzyme) is synthesized after the burst of RNA synthesis. Experiments have illustrated three types of molecular response to thyroid hormone. One set of genes increases its low level of transcription in reply to either natural or thyroxine induced metamorphosis. Another set of genes decreases its rate of transcription, whereas a third set of genes remains unaffected by thyroid hormones. Mori and Coworkers (1979) have illustrated that much of the increase in Carbamoylphosphate synthase can be attributed to increased transcription from the gene. So metamorphosis appears to some extent to be controlled at the transcriptional level. Other evidences also indicate the capability of thyroid glands to regulate gene activity at the level of transcription. This does not mean that transcription is the only level of gene regulation, operative during metamorphosis, but it is obviously an important one.
Select an industry. Using the Porter's Five Forces of Competition, illustrate the forces to the industry you selected. Explain the rational you used for determining the necessary f
write and explain the essentials of management giving practical examples
A Make or Buy Analysis Managers at Wagner Fabricating Company are reviewing the economic feasibility of manufacturing a part that it currently purchases from a supplier. Forecas
1. If the design tolerance limits for the process are 9.7/11.2, determine the process capability indices C p and C pk . Comment on the values obtained. 2. 1000 items produced
Q. Explain the strategic supply wheel according to Cousins? The 'strategic supply wheel' suggests that this is imperative to keep an alignment of corporate goals along with the
Should Galanz continue to expand its capacity through outsourcing arrangements? How does the Pursuit of outsourcing align with its operations strategy?
1. Develop an ld score for the current layout. What problems can you identify with the current layout? 2. Use trial and error to come up with a better layout that lowers the ld
Organizing Process Flows Five types of process are distinguished. They are Project Production System Job Shop Production system Batch Production system
To determine the standard working time for a special job, following observation data is collected: Observation 1 2 3 4 5 6 7 8 Time (in second) 17 18 15 14 13 15 16 13 a) If the pe
You have just been notified by the Student Aid and Scholarships Office that you would receive a regents scholarship of $2000 for the coming academic year. Furthermore, your applica
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd