Molecular response to thyroid hormones, Operation Management

Assignment Help:

Molecular Response to Thyroid Hormones during Metamorphosis

Thyroid hormones can cause obtainable tissues to break down or can remold the tissues to their adult function. The liver cells of the tadpole for instance are not destroyed and replaced during metamorphosis. In place of their structure is remodeled. This change is accompanied by dramatic raise in ribosomal and messenger RNA synthesis. The rate of protein synthesis also increases nearly 100 folds in four hours of thyroid hormone stimulation. Many of the new mRNAs are those that code for new functions of the liver. The main increase in protein synthesis appears to come from the transcription of new m-RNAs.

Carbamoylphosphate synthase (a urea cycle enzyme) is synthesized after the burst of RNA synthesis. Experiments have illustrated three types of molecular response to thyroid hormone. One set of genes increases its low level of transcription in reply to either natural or thyroxine induced metamorphosis. Another set of genes decreases its rate of transcription, whereas a third set of genes remains unaffected by thyroid hormones. Mori and Coworkers (1979) have illustrated that much of the increase in Carbamoylphosphate synthase can be attributed to increased transcription from the gene. So metamorphosis appears to some extent to be controlled at the transcriptional level. Other evidences also indicate the capability of thyroid glands to regulate gene activity at the level of transcription. This does not mean that transcription is the only level of gene regulation, operative during metamorphosis, but it is obviously an important one.


Related Discussions:- Molecular response to thyroid hormones

Prepare a report about process and the process capability, 1. A company man...

1. A company manufactures 1Kg bags of grout (used in tiling).  The specification is given in grams and is 1002.0 ± 7.5 g.  The following data has arisen in a process investigation.

Explain personality traits affect management and leadership, Your managemen...

Your management team has been retained by a senior manager who is concerned about the effectiveness of his managers and their leadership abilities. He would like you to develop a t

Advantages of the enterprise-wide systems, Q. What are the advantages of th...

Q. What are the advantages of the enterprise-wide systems? Benefits of Enterprise-wide systems (ERP) systems: a. In this system integration of software applications can easi

Explain organizations periodically turn to, Organizations periodically turn...

Organizations periodically turn to _________ to meet demands for talent brought about by business growth and a desire for fresh ideas, or to replace employees who leave.

Types of process designs, Types of Process Designs The basic type of p...

Types of Process Designs The basic type of production system and the finished goods inventory policy to be used must be decided at the earliest stages of process planning. The

Explain information and communication technologies, 1. One consequence of g...

1. One consequence of globalization is increased competition. 2. Due to globalization, organizations often locate parts of their operations in different countries. 3. Due to global

Explain in what kind of ways did these mangers respond, In what kind of way...

In what kind of ways did these mangers respond to these challah for example in their approaches to planning leading organizing and controlling?

Production control function, Production control Function 1. Dispatchi...

Production control Function 1. Dispatching : Dispatching may be  defined as setting  production activities in motion through  the  release  of orders ( work order shop order)

I need major help, Read “Space Age Furniture Company” in Chapter 9 of your ...

Read “Space Age Furniture Company” in Chapter 9 of your text. Respond to the following and include any Materials Requirement Planning (MRP) calculations: Develop an MRP for Space

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd