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Methods yielding mixture of amines - Hofmann's method
Hofmann's method: The mixture of amines (1°, 2° and 3°) is made by the alkylation of ammonia along with alkyl halides.
The primary amine can be ready in a good yield by using a large excess of ammonia. The process is as well known as ammonolysis of alkyl halides. It is also known as a nucleophilic substitution reaction.
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Formic acid is a weak acid along with a pKa of 3.75. The name comes by the Latin term "formica" ("ant") since this is very plentiful into the secretions of several species of ants,
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advantage of his theory?
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