Mechanism of enzyme action, Biology

Assignment Help:

Mechanism  of Enzyme Action

 The action of enzymes is to lower  the activation energy  or threshold  of their substrates which. Therefore  become  activated and   react  with  the other reactants  .The  specific amino acid  sequence and molecular shape of the  enzyme  are of primary  importance in this function but its  mechanism is not yet properly under stood  ,The main  views  have been  expressed  t explain  this mechanism .

1. Lock and key or Template Hypothesis: Emil Fischer  1894  hypothesized  that each  enzyme molecule  has a specific and  rigid  active  site upon its surface .A reactant molecule having a matching  geometrical  configuration   only  can fit into this  active  site  of enzyme  like  a key fitting   into a lock forming an unstable enzyme substrate complex ,This  linkage actives the  substrate molecules  to react readily with  the other reactant of the  reaction

2. Induced fit Model Hypothesis: The  lock and key model has been  modified  by koshland 1971 and his co-workers  who  have suggested that the active silt  of an enzyme  molecule  is flexible. As  the specific  substrate molecule links with the  enzyme  molecule the latter undergoes conformation changes  so that the  fit  is improved the  reactive groups of enzyme  molecule move to their  proper sites.


Related Discussions:- Mechanism of enzyme action

Decomposers - biotic components, Decomposers - Biotic Components Also ...

Decomposers - Biotic Components Also known as saprotrophs. Mostly, these are microscopic and are heterotrophic in nature. Decomposer organisms obtain their energy and nutrient

Partial pericardiectomy-pericardial effusion, Partial Pericardiectomy :  ...

Partial Pericardiectomy :  The approach can be either by a left anterolateral thoracotomy or median sternotomy. For pyogenic pericarditis with adhesions and loculations a par

Neuroglia cells, NEUROGLI A CELLS (Rudolf Virchow, 1846) - Occurs i...

NEUROGLI A CELLS (Rudolf Virchow, 1846) - Occurs in the C.N.S. The cells are less than neurons. Neuroglia cells are of four types - (i) Oligodendrocytes - Occ

Define integrity of epithelial tissues, Define Integrity of Epithelial Tiss...

Define Integrity of Epithelial Tissues? Vitamin A is essential for the integrity of the mucous-secreting cells. In fact vitamin A maintains the health of epithelial cells that

Mention the main cause of air pollution in metro cities, a) Mention the mai...

a) Mention the main cause of air pollution in metro cities. Write any three ways by which it can be decreased. b) How did Eli Lilly synthesize the human insulin? Mention

Define filming projection and technique, Q. Filming Projection and Techniqu...

Q. Filming Projection and Technique? Biplane ventriculography is preferred over single plane ventriculography because it gives more information without additional risk to the p

What do you mean by oesophagitis, Q. What do you mean by Oesophagitis? ...

Q. What do you mean by Oesophagitis? We already know that oesophagus is a muscular tube 25 cm in length and basically helps in transporting the food from the mouth to stomach,

Ant species in the two regions, Calculate a 95% confidence interval for the...

Calculate a 95% confidence interval for the difference among the average numbers of ant species in the two regions. Compare your results to SPSS output and interpret the confidence

Cryptophytes - classes of life form, Cryptophytes - Classes of Life Form ...

Cryptophytes - Classes of Life Form Perennating buds or shoot apices are buried in the ground at a distance from the soil surface that varies in different species. The buds ar

Explain about the foods effect on drug utilization, Explain about the Foods...

Explain about the Foods Effect on Drug Utilization? The following illustrations highlight the effect of food on drug utilization. Liver and green leafy vegetables can decrea

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd