Maximal conductances and reversal potentials, Mechanical Engineering

Assignment Help:

By introducing their model of neural excitability in 1952, Alan Lloyd Hodgkin and Andrew Huxley not only shed light on the mechanism underlying a very important phenomenon in Physiology (i.e. the generation and propagation of electrical signals in neurones), but they also introduced a mathematical formalism for modeling similar phenomena in a large variety of excitable cells. Therefore, it is only natural that there is a large number of neural models that are built on the basic concepts introduced by the two aforementioned researchers. One such model is the following:

2005_Membrane capacitance.png

where IL, INa, IK, IA and ICaT are leakage, transient sodium, persistent potassium, transient potassium and transient calcium currents, respectively, and I(t) is any time-dependent externally injected current. The dynamic activation and inactivation variables x, where x 2 fm; h; n; a; b;M;Hg follow rst order relaxation kinetics:

1139_Membrane capacitance1.png


Related Discussions:- Maximal conductances and reversal potentials

What is the velocity of the crosshead - crank, What is the velocity of the ...

What is the velocity of the crosshead - crank: In the slider crank mechanism shown in Figure, the crank is rotating clockwise at 120 revolution/minute. What is the velocity of

Stresses., temparature stresses in composite bars

temparature stresses in composite bars

Evaluate secure axial load, Evaluate secure axial load: A small piece ...

Evaluate secure axial load: A small piece of ISA (200 × 100 × 15) angle carries a compressive load, the line of action of which coincides along the intersection of the middle

Shielded metal arc welding, Shielded Metal Arc Welding   Single pass...

Shielded Metal Arc Welding   Single pass fillet welds upto ¼" (6.4 mm) maximum and ¼" groove welds made with a single pass or a single pass each side, may be made by using a

Explain index jig, Explain Index Jig? 1. This type of jig, as the...

Explain Index Jig? 1. This type of jig, as the name suggests, incorporate a suitable indexing mechanism, by means of which the work piece can be indexed to required posit

OPITZ alternative, I am looking for an alternative coding system to the OP...

I am looking for an alternative coding system to the OPITZ coding system for my essay thanks

What is forced draft fan, Q. What is Forced Draft Fan? Fan shall comply...

Q. What is Forced Draft Fan? Fan shall comply with API 673 as supplemented by the following: (para. references are to API 673). Where the intake air is unfiltered, the Vendo

Compressive stress, Compressive Stress: The stress induced in a body, ...

Compressive Stress: The stress induced in a body, when subjected to two equal and opposite pushes as shown in figure (a) as a result of which there is an decrease in length

Balancing, what do you mean by static and dynamic unbalance in machinery

what do you mean by static and dynamic unbalance in machinery

Insulation on flanges and valves, Q. Insulation on Flanges and Valves? ...

Q. Insulation on Flanges and Valves? Valves, flanges, and unions shall not normally be insulated unless specified by OWNER. All other fittings are to be insulated. Fittings

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd