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According to the Nernst equation, the equilibrium potential for any ion (Eion) distributed across a membrane is dependent on the internal (Ionin) and external (Ionout) concentrations of the ion (in moles or grams/liter), the valence of the ion, z (an integer), the absolute temperature (°K), Faraday's constant (96,500 coulombs/mole) and the universal gas constant R according to the following relationship: Eion = (RK/zF)2.303 log ([Ion]out/[Ion]in) Assuming that the equilibrium potential for sodium ion across a skeletal muscle is +66 mv at a temperature of 37°C when the external concentration is 145 mM and the internal concentration is 12 mM, evaluate both the magnitude and appropriate units for the universal gas constant, R.
function of cell coat
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Outline the importance of buffer systems in the human body. In addition, describe the main biological buffer systems and how they function.
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