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Hodgkin-Huxley Fast Subsystem
1. Explain why replacing the extracellular Na+ with choline has little effect on the resting potential of an axon. Calculate the new resting potential with 90% of the extracellular Na+ removed. Why is the same not true if K+ is replaced? (Assume the conductances are constant.)
2. Show how the Hodgkin-Huxley fast subsystem depends on the slow variables: i.e., show how the v nullcline moves as n and h are changed, and demonstrate the saddle-node bifurcation in which ve and vs disappear.
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Calculate number of cycles to fracture: If the plastic deformation is taken into consideration calculate number of cycles to fracture in above Example. Solution Δ K I
Complete the following problem from the text by Megson. Note that since the answers are given, it is essential that you show and justify all work to receive full credit. Required
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