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Hodgkin-Huxley Fast Subsystem
1. Explain why replacing the extracellular Na+ with choline has little effect on the resting potential of an axon. Calculate the new resting potential with 90% of the extracellular Na+ removed. Why is the same not true if K+ is replaced? (Assume the conductances are constant.)
2. Show how the Hodgkin-Huxley fast subsystem depends on the slow variables: i.e., show how the v nullcline moves as n and h are changed, and demonstrate the saddle-node bifurcation in which ve and vs disappear.
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