Genetic defect in pyruvate dehydrogenase, Biology

Assignment Help:

Genetic Defect in Pyruvate Dehydrogenase

A defed in any of  the protein subunits of PDH can result in decrease or complete loss of  activity. Severe cases are usually fatal. Symptoms  of deficiency include:

a)  Lactic acidosis, and

b)  Neurologic disorders.  .

Chronic alcoholics suffer  fiom  the deficiency of,thiamin,  which results  in the  accumulation of pyruvic acid. Excess pyruvate is also reduced to lactate leading to potentially fatal pyruvic and lactic acidosis.

 


Related Discussions:- Genetic defect in pyruvate dehydrogenase

Is geometric isomers have the same connectivity, Geometric isomers: Select ...

Geometric isomers: Select one: a. Have the same molecular weight b. Have the same connectivity c. Have a different configuration about a double bond d. All of the above

Define work capacity that is relevant to sports nutrition, Define Work Capa...

Define Work Capacity that is relevant to sports nutrition? There are generally two areas of work capacity that is relevant to sports nutrition one is aerobic capacity and the o

Why d scientists pick hydrogen as the basis for mri scanning, Why d scienti...

Why d scientists pick hydrogen as the basis for MRI scanning? Name of the human body that do not appear in an MRI scan. Explain thermal stratification? How does thermal stratifi

Chemotaxis - modes of cell movement, Chemotaxis - Modes of Cell Movement ...

Chemotaxis - Modes of Cell Movement Chemotaxis considers to me directed movement of cells in response to a concentration gradient of a chemical factor in solution. An instance

Give example of ex-situ conservation, Which one of the following is an exa...

Which one of the following is an example of ex-situ conservation? 1. Wildlife sanctuary 2. Seed bank 3. Sacred groves 4. National park Seed bank

Define the poverty and hunger as a causes of malnutrition, Define the Pover...

Define the Poverty and hunger - mutually causes, devastating effects? Measures of food deprivation, nutrition and poverty are strongly correlated. Countries with a high prevale

Which bone forms the non-moving muscle, Which bone forms the non-moving mus...

Which bone forms the non-moving muscle attachment in (a) the hip joint, (b) the shoulder joint, (c) the ankle joint?    (a) The pelvic girdle gives the non

Distinction between breathing and respiration, (a) What is the distinction ...

(a) What is the distinction among 'breathing' and 'respiration'? (b) What part do 'ventilation' and 'gaseous exchange' play in these processes?   (a) Breathing i

Determine general principles of allergy management, Determine General Princ...

Determine General Principles of Allergy Management? The four general principles of allergy management include: 1.  Avoid factors that cause symptoms. 2.  Use appropriate

Preparation of dilutions - standard or total plate counts, Define Preparati...

Define Preparation of Dilutions - Standard or Total Plate Counts? 1. Serial dilution of homogenized sample in an appropriate diluent. Preparation of dilutions - Decimal dilu

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd