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Formation of esters (Esterification)
(1) The reaction is shifted to the right via using excess of alcohol or removal of water by distillation.
(2) The reactivity of alcohol towards esterification.
tert-alcohol < sec-alcohol < pri-alcohol < methyl alcohol
(3) The acidic strength of carboxylic acid plays just a minor role.R3CCOOH2CHCOOH2COOH3COOH
How many grams of silica gel and plaster of paris and volume of water is needed to have a preparative TLC?
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what is the hybridization of transion state of sn2 rection
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