Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Calculate the natural frequency, (a) Calculate the natural frequency of mas...

(a) Calculate the natural frequency of mass m = 1 Kg placed at one end of a cantilever beam of negligible mass. Length of cantilever = 500 mm, d = 30 mm, b = 20 mm, E = 210x10 9 N

Illustrate the specification of pddi, Illustrate the specification of PDDI ...

Illustrate the specification of PDDI (i)  The 3-D geometry of the product which is defined by a set of curves, surfaces and volumes. (ii) The topology which describes the se

Types of holons, Types of Holons The four major types of holons are: ...

Types of Holons The four major types of holons are: Order holons Product holons Resource holons Staff holons Considering the cooperative aspect of the

Hot and cold working, What is the difference between hot and cold working

What is the difference between hot and cold working

#title.cutting tool life, what is relation between tool life and cutting sp...

what is relation between tool life and cutting speed?

Som, Bending moment

Bending moment

brazing, Brazing Brazing is a group of welding processes, which produces...

Brazing Brazing is a group of welding processes, which produces, coalescence of materials by heating them to a specific temperature and by using a filler metal having a liquids a

Draw the gas welding system, Draw the Gas welding System and label its part...

Draw the Gas welding System and label its parts. Illustrate the several types of flames used in gas welding along with temperature range.

If o ring found to be leaking-oil seal is found be leak, If "o" ring is fou...

If "o" ring is found to be leaking or oil seal is found to be leaking check as mentioned: If "O" ring found to be leaking change "O" rings. If oil seal found to be leaking check o

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd