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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
casting is better than steel
Q. Define the Moving boat method? Moving boat method has been more recently evolved and tested in the U.S.A. and holds promise in measurement of discharge of big rivers and tid
The overall size of the crane must not be changed. The height and reach of the loading point is to remain the same . Original parts must remain and you are allowed additions such
2. Assume that the river has been selected as the source of raw water for the 2.0mgd demand. a. Surface water has low alkalinity, high turbidity. The distribution system is cast
The following specification is used for the design of a flanged coupling between two coaxial shafts: Speed: 650rpm Power transmitted: 550 kW Bolt Diameter: 12 mm Pit
Explain Gauge Pressure (P gauge ) Gauge Pressure is the pressure of a fluid contained in a closed vessel. It is all time more than atmospheric pressure. It is calculated by an
i have an assignment due tomorrow
Define universal portable radial drills Drilling machine is mounted on a trolley base to have a greater degree of mobility. In order to move the machine to any position on or a
What is vabretion defects?
what is the least count of following instrument? vernier caliper micrometer bevel protractor dial
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