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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
hi i have an assignment in control system can u do it ?
spring combined gravity governor
It is essential to select a flat belt drive for a compressor running at 720 r.p.m which is driven by a 25kW, 1440 r.p.m. motor. Space is available for a distance of 3m. The belt is
how we can design a shaft for gear box
Develop a computer program that can be used for internal flow analysis in SI units. The program should be able to: ? Get the required input data from the user ? Decide the flow ty
Explain Gear Forming In gear form cutting, cutting edge of the cutting tool has a shape similar with the shape of the space among the gear teeth. Two machining operations, mill
What is carbonation.? Discuss its stability s mathod of formation
Are the types of pumps selected (base mounted, in-line)? Locate pump on discharge side of boiler. Flexible connector used. Valving indicated, isolation valve on suction and dis
Scalar and Vector quantities: A quantity is a scalar if it is completely defined by its magnitude alone. For example: Length, area, and time. While quantity is said to be vect
full defination
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