Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Specific heat - thermodynamics, Specifi c Heat: The specific Heat of ...

Specifi c Heat: The specific Heat of a solid or liquid can be usually defined as heat required for raising unit mass through one degree temperature rise. That is,   dQ = m

Torsion , in the torsion equation the term j/r is called

in the torsion equation the term j/r is called

Welding head, Welding Head Submerged arc welding head consists of the wir...

Welding Head Submerged arc welding head consists of the wire spool, wire feed system, flux delivery hopper and electrical contact nozzle. The electrode wire is unwound from the s

Define carbon steel, Q. Define Carbon steel? At ambient temperatures an...

Q. Define Carbon steel? At ambient temperatures and under dry conditions, caustic is not particularly corrosive and can be handled in carbon steel. However, stress corrosion c

Force equilibrium equation, When you arrive at Duke's Dude Ranch, you are g...

When you arrive at Duke's Dude Ranch, you are greeted by the large wooden sign shown.  The left end of the sign is held in place by a bolt and the right end is tied to a rope that

Optimization, what are the different method for worm gear optimization

what are the different method for worm gear optimization

Determine the deflection of the spring, Determine the deflection of the spr...

Determine the deflection of the spring: A close coiled helical spring deflects 25 mm under a certain axial load. Determine the deflection of the second spring under the simila

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd