Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Beam, calculate the vertical reaction at A in Newtons

calculate the vertical reaction at A in Newtons

What could be the characteristics of tool materials, (a) What could be the ...

(a) What could be the characteristics of tool materials. (b) Describe several tool materials with their composition.

Shear and moment diagrams, Shear and Moment Diagrams Determine the anal...

Shear and Moment Diagrams Determine the analytical solution for the maximum stress of the beam shown; compare with stress results from Solid Works. Draw shear and moment diagra

Why we use cold working, Q. Why we use cold working? Cold working takes...

Q. Why we use cold working? Cold working takes place below the recrystallization temperature, and therefore is fundamentally different at the atomic level with effects up to th

Describe about austenitic stainless steels, Q. Describe about Austenitic st...

Q. Describe about Austenitic stainless steels? Austenitic stainless steels (300 series) generally exhibit very good corrosion resistance in sulphuric acid service for low conce

Maximum bending moment, Maximum Bending Moment: The SF changes sign at...

Maximum Bending Moment: The SF changes sign at A, among A and B and at B. Let a section XX at a distance x from the end C as illustrated in Figure SF at section XX, F x

#tool life, #tool life formular for diferent n values

#tool life formular for diferent n values

Matlab Applied Optimization Problem, A fenced enclosure consists of a recta...

A fenced enclosure consists of a rectangle of length L and width 2R, and a semicircle of radius R, as shown in Figure P20. The enclosure is to be built to have an area A of 1600 ft

Newton''s second and third law of motion, Newton's second and  third law o...

Newton's second and  third law of motion: Newton's second law of motion: If resultant force is acting on particle is not zero, and then acceleration of particle will be prop

Gyroscope, what is principle of gyroscope

what is principle of gyroscope

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd