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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Evaluate the motion of the system: If in above Example, the block A is resting on an inclined plane at 45 o to horizontal as illustrative in Figure, find out the motion of th
A piston-cylinder assembly fitted with a paddle wheel contains air, initially at p1=30 lbf/in2, T1=540 °F, and V1=4 ft3. The air undergoes a process to a final state where p2=20 lb
In most hardware stores, you can find what has known as a Heat Gun. Hold the heat gun about 6 inches away from the acrylic you intend on bending say the bumper on a car. They are p
V elocit y Ratio for Open Belt Drive: Figure Consider a simple belt drive (that is one driver and one follower) as shown in the figure given below Let D 1
SPOT WELDING In this type of welding, after proper cleaning of the surfaces, the metals to be welded are kept one above the other and two copper electrodes are kept on both sid
all lines on psychrometric chart
EDM Machine under varying Cutting Condition a) All the experiments have been conducted on a Z numerically controlled (NC) oil die- sinking EDM Machine. b) The EDM Machine is
Flight of the Bumblebee Railroad train T a leaves station A at a uniform speed of 30mph toward station B. Train Tb leaves station B at a uniform speed of 20mph toward station
How to describe sensitivity of Governors
Bhasker operates a retail shop and sells the high priced "Hot Food" thermoware. Each unit I priced at Rs.250. Experience has shown that the weekly demand schedule for items is as f
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