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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Concentrate d or Point Load: How many types of load are acting on the beam? A beam is usually horizontal and the loads acting on beams are usually vertical. The followi
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Internal Energy (U): It is the energy possessed by the system on account of its configurations, and motion of atoms and molecules. Not like potential energy and kinetic energy
what is diflection of beam
I have literature review and the title is "the effect of fluid cooling on the performance of building integrated photovoltaic thermal systems. Using some BIPVT prototypes measure
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Ratio of applied stress and yield stress: What should be the ratio of applied stress, s, to yield stress s Y in a large thin plate so that plastic spread along lint of crack
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Are there jobs in the field of Mechanical Engineering that incorporate the outdoors? I am an outdoorsman for one, and a tradesman at heart and am currently a Mechanical engineering
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