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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Throughout this project, you'll find questions that will direct you to think about how you're creating the drawing. Although you should not submit the answers to these questions, a
Terminal Nut: This is a detachable type of terminal nut. The high tension (HT) cord is connected here. This is also available in non-detachable type. Figure: Spark Plug
Question. In the system shown below, the force exerted by the free jet issuing from the sharp-edged circular nozzle and impinging on the small circular plate is just su±cient to k
determine the shear force and bending moments of 4KN fprce
Torsion equation derivation
Q. Explain about Ducts and Flues in steam generators? All air ducts and gas flues connecting the forced draft fan, fan intake silencer, preheater, and transition piece at the g
AEROSPACE APPLICATIONS The need for EBW as a critical fabrication process in realising elements and assemblies for spacecraft and launch vehicle programmes due to the foll
What are the points that should be kept in mind during forging design? Some of the points which must be followed while forging design are: > A radial flow of fibers or grain
What is wave? How many type of the waves?
Pneumatic system is a system that uses air to power something. For example, have you seen the tube systems at bank drive-up tellers? Air is used to drive the tubes back and forth f
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