Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Calculate the motor efficiency, A 4- pole DC motor is known to have an arma...

A 4- pole DC motor is known to have an armature resistance of 0.5 Ω, and is operated as a separately excited motor. (a)  When the motor is connected to a 250V DC supply with no

Select a flat belt drive, It is essential to select a flat belt drive for a...

It is essential to select a flat belt drive for a compressor running at 720 r.p.m which is driven by a 25kW, 1440 r.p.m. motor. Space is available for a distance of 3m. The belt is

Waste water treatment, Q. Waste Water Treatment? Typically, there are a...

Q. Waste Water Treatment? Typically, there are a number of waste water streams which need to be treated before disposal to land or water. Depending on the nature of contaminati

Economic order quantity, Economic Order Quantity: Assume an economic o...

Economic Order Quantity: Assume an economic order quantity case where annual demand D = 500 units, economic order quantity Q = 100 units, the wanted probability of not stockin

Illustrate the cad interface, CAD*I Interface The CAD*I interface was d...

CAD*I Interface The CAD*I interface was developed within the framework of the ESPRIT Project 322 of the European Commission. The project was started in 1985 and had duration of

Stresses., temparature stresses in composite bars

temparature stresses in composite bars

Show seismic loads for ground supported equipment, Q. Show Seismic Loads Fo...

Q. Show Seismic Loads For Ground Supported Equipment? V = C s W is the governing equation for horizontal seismic base shear of ground supported equipment. C s  = 1.2A v S/(RT

Explain the working of michelsons interferometer, Explain the working of Mi...

Explain the working of Michelson's interferometer. How circular fringes he produced with it. (a) What are antireflection films and interference filters? (b) Find the reflecti

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd