Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Illustrate working of double acting steam engine, Illustrate working of dou...

Illustrate working of double acting steam engine. What is its diagram factor and thermal efficiency?

Design of a filament winding machine, How can I achieve a back and forth mo...

How can I achieve a back and forth movement of carriage system. How can I reverse the motor to go back and forth.

Illustrates the concept of bearing capacity of soil, Illustrates the concep...

Illustrates the concept of bearing capacity of soil? The concept of bearing capacity of soil is the very essence of design and analysis of shallow foundations. In order to inve

What do you mean by stage discharge relationship, Q. What do you mean by St...

Q. What do you mean by Stage Discharge Relationship? Regular recording of discharges over a period of time is essential for estimation of water resources of river basins and su

Data and tasks - rough-cut capacity planning, Expected quarterly sales in Y...

Expected quarterly sales in Year 1 (vehicles) The work content of a single unit of each product in each process has been estimated at: Using MS-Excel, calculate the workloads

Welding of pressure parts in boilers, This section covers welding of pressu...

This section covers welding of pressure parts including those non-pressure parts when welded to pressure parts. All welding design functions necessary within the contract shall be

Determine the types of evolutionary cad applications, Determine the Types o...

Determine the Types of Evolutionary CAD applications Evolutionary CAD applications supporting design can be categorized into three types - traditional, knowledge based, and im

SOM, 01-- what is the scope of som? 02-- how can we learn and understand sh...

01-- what is the scope of som? 02-- how can we learn and understand shear force and bending moment diagram?

Surface modeling, SURFACE MODELING: The process of modeling is built m...

SURFACE MODELING: The process of modeling is built much easier for a mathematical description of an object or at least on a part of the object might be applied. Surfaces might

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd