Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Level of safety organization, Level of Safety Organization This level ...

Level of Safety Organization This level comprises representatives of safety departments working at shop floor level or along with workers. The personnel will in fact implement

Metal transfer in co2 welding, METAL TRANSFER IN CO2 WELDING In CO 2 wel...

METAL TRANSFER IN CO2 WELDING In CO 2 welding, two distinct types of metal transfers are identified viz. short circuiting transfer and free flight globular transfer. Short Cir

Surface chemistry and electrochemistry of membranes, explain surfacechemist...

explain surfacechemistry and electrochemistry of membranes?

Strength of materials, simply supported beam subjected to point loads resul...

simply supported beam subjected to point loads results

Module site installation preparation, Q. Module Site Installation Preparati...

Q. Module Site Installation Preparation? The following tasks shall be accomplished at the Facility site prior to setting the modules on the piles: After module support piles

Show material selection process, Q. Show Material selection process? • ...

Q. Show Material selection process? • Design life shall be based on project design criteria and normally 10 to 15 years' service life specified for well pads, 20-25 years for C

Types of culverts - causeway and bridges, Types of Culverts: Culverts ...

Types of Culverts: Culverts are constructed with various materials and to different designs. The popular forms are : (a) Temporary stone scuppers (b) Stone slab culverts

Gears, what is the practical application of worm and worm gear

what is the practical application of worm and worm gear

Mechnics of solids thick cylinder, a compound cylinder is composed of a tub...

a compound cylinder is composed of a tube of 250mm internal diameter at 25mm wall thickness.it is shrunk on to a tube of 200mm internal diameter. the radial pressure at the junctio

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd