Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Shear and moment diagrams, Shear and Moment Diagrams Determine the anal...

Shear and Moment Diagrams Determine the analytical solution for the maximum stress of the beam shown; compare with stress results from Solid Works. Draw shear and moment diagra

Determine the need for insulation, Q. Determine the need for insulation? ...

Q. Determine the need for insulation? Equipment and piping shall be insulated as required for heat conservation, process heat control and personnel protection. The temperatu

Kinematics, Kinematics: We have seen the various types of motions whic...

Kinematics: We have seen the various types of motions which may be undergone by particles and rigid bodies. You may be able to understand the relationships of displacement, ve

Sequecing problm, What is the sequence of this problem Job- 1 2 3 4 5 6 7 ...

What is the sequence of this problem Job- 1 2 3 4 5 6 7 M/c M1 4 13 16 7 11 12 10 M2 9 11 11 7 13 2 4

Stresses., temparature stresses in composite bars

temparature stresses in composite bars

Newton law of motion - third law, Newton law of motion - Thir d Law F...

Newton law of motion - Thir d Law Force of action and reaction between the bodies which are interacting are equal in magnitude, opposite in direction and have same line of ac

Evaluate the specific enthalpy - thermodynamics, Evaluate the specific enth...

Evaluate the specific enthalpy - thermodynamics: Steam is being generated in a boiler at a pressure of 15.25 bar. Calculate the specific enthalpy when ( i )  Steam i

Evaluate the least pull, Evaluate the least pull, through the center of whe...

Evaluate the least pull, through the center of wheel: A uniform wheel having 600 mm diameter, weighing 5KN rests against rigid rectangular block of 150mm height as shown in t

Key words related to railway line, Keywords related to railway line: ...

Keywords related to railway line: Railway Station : A facility along a railway line where trains stop and passengers are serviced, and cargo is handled. Platform : A fa

High pressure die casting process, what is the working princile of high pre...

what is the working princile of high preesure die casting process

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd