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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Careful consideration of the bioreactor agitation and aeration system is required in order to maintain a homogeneous environment and provide sufficient oxygen transfer rates to mee
Tension in the string and acceleration of body: The two bodies weighing 300N and 450N are hung to two ends of the rope passing over an ideal pulley as shown in the figure giv
The Mechanical Design Engineer/Specialist shall be responsible for mechanical design calculations that are required to ensure that the end product complies with all applicable code
Diff. B/w edge and screw dislocation
Derive the equation for pure bonding of beam (simply)
give some basis of above topic
what are the anti refection coating.expretion for thicknessrefractive index of coating material to act as anti reflacting coating
surface angle
High Duty Tool and Die Steels: High duty punching tools or dies are made out of a lot of various steels of fairly high alloying contents. High-carbon high-chromium die steel
Why is porter governor more sensitive than Watt Governor even the former has got an additional weight which will require more force to move sleeve than Watt governor?
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