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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
A 1.5m long column has circular cross-section of 5cm diameter. One of the end of the column is fixed in the position and direction and other end is free. Taking factor of safety as
state the purpose and function of work holder
common formula for first law of thermodynamics #Minimum 100 words accepted#
For my senoir design project, I chose a scissor lift table. My issue is finding a a roller to fit my design with .1 in od, press fit on >5 in shaft that can support 125-150 lb/sh
Write down the uses of following tools and make neat sketches of the same : (a) Vernier Caliper (b) Steel Rule
An open test tube at 293 K is filled at the bottom with 24.2 cm of Hg, and 11.2 cm of water is placed above the Hg. Calculate the pressure at the bottom of the test tube if the atm
Thyristor: The thyristor is just like an ordinary diode. Thyristor
analyse grublers criterion
applications of parallelogram
(a) Briefly explain the various efficiency terms associated with an engine. (b) A four cylinder engine running at 1200 rpm delivers 20 KW. The average torque when one cylinder w
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