Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Design requirements, A steel member supported by a tie bar has a load of 15...

A steel member supported by a tie bar has a load of 15 000 lbs on it. If the force on the steel member of 1.2 in 2 cross section is 14,180 lbs and the force on the tie bar of diam

Yes, Which type of study require for mechanial engineering

Which type of study require for mechanial engineering

Explain about the CAD system, Explain about the CAD system. CAD systems...

Explain about the CAD system. CAD systems generally require considerable processor power and a number of output and input devices; for instance: - Light pens - Large scre

Woodwork, with the aid of notes and sketches describe how you would transfe...

with the aid of notes and sketches describe how you would transfer the design from a sheet of paper onto the wooden panel prior to carving

Clutch cable routing-Clutch Complaint, Clutch cable routing : Ensure that ...

Clutch cable routing : Ensure that the cable is routed as per standard routing, through the brackets provided.

Sewage treatment, Q. Sewage Treatment? Unless located in a metropolitan...

Q. Sewage Treatment? Unless located in a metropolitan area, it is common for plants to have sewage treatment facilities for disposal of sewage and grey water generated in the p

Design stairways - ladders and platforms, Q. Design Stairways - Ladders and...

Q. Design Stairways - Ladders and Platforms? Stairways, rather than ladders, should be provided for main access to elevated structures. Ladders should be reserved for isolated

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd