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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
How the boiler are classified? Sketch and define the babcock & Wilcox boiler and also Compare the water tube boiler and fire tube?
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#questicalculation of shear fon\rce and bending moment..
Q. Cyclic Service for vessels? The required service for all vessels shall include consideration of cyclic service. Batch operation vessels, for example, quite frequently fall i
Determine strap beam with suitable demonstration. Here observe that R e becomes greater than P e by a magnitude of V while R i becomes less than P i by a magnitude equal to
alternative theorems for lamis theorem
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Orthographic Projections: As you learned previously about the theory of projection of points, planes and lines, the next significant is the projection of solids that have thre
Calculate the overall fraction defective from all of sample: ABC insurance company desires to design a control chart to check whether insurance claim forms are being correctly
Define the process of SAW (submerged Arc welding). And also explain its advantages and disadvantages.
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