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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
How we could build the working model of hartnell governor?
Wheels: The wheel, along with the tyre has to take the vehicle load, provide a cushioning effect (to protect against force or shock) and cope with the steering control. The wheel
Calculate strength coefficient: A copper specimen of 64 mm gauge length and 12.80 mm dia. was tested in tension. Following two diameters were recorded in the plastic range of
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Q. Define Non - consumable electrode? These types of electrodes are prepared from high melting point materials. Mainly carbon, pure tungsten and its alloy are used for electrod
What are the factors responsible for the development of newer tool materials. Explain several materials used for cutting tools. List four kinds of tool wear.
Schedule Evaluation Each continuations of a partial schedule that are produced in step 1 are ranked as per to their respective cost function. This cost function might be dissim
Resolving all of the forces normal to the inclined plane: A body weighing 500 N is resting on an inclined plane making an angle of 30 o with the horizontal. The coefficient o
how i can know moulair plant calculation?
what is cloud chamber..
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