Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Describe about carbon steel, Q. Describe about Carbon Steel? Steel havi...

Q. Describe about Carbon Steel? Steel having no specified minimum quantity for any alloying element (other than commonly accepted amounts of manganese, silicon, and copper) and

Conventional priority rules, Conventional Priority Rules  The standard ...

Conventional Priority Rules  The standard solution for production scheduling (routing and sequencing) difficulties is the utilization of priority rules. A priority rule is an o

Show the welding processes and restrictions, Q. Show the Welding Processes ...

Q. Show the Welding Processes and Restrictions? Welding may be performed manually, semi-automatically and or automatically using any process or combination of processes accepte

Torsion, series shaft and parallel shaft

series shaft and parallel shaft

Find out the quality, Find out the quality: ABC industries manufacture...

Find out the quality: ABC industries manufacture X-band radar scanners utilized to detect speed traps. The printed circuit boards in the scanners are bough from an outside ven

Determine equivalent maximum shear stress in spring, Determine equivalent m...

Determine equivalent maximum shear stress in spring: A close coiled helical spring contains a stiffness of 10 N/mm. Its length while fully compressed, with adjacent coils touc

Derive mathematical equation for bernoulls equation, Derive mathmatical equ...

Derive mathmatical equation for Bernoull's equation, what are the application of Bernoull's equation and illustrate any one.

Introduction to service sector , INTRODUCTION: Service sector, you shall s...

INTRODUCTION: Service sector, you shall study about the growth of service sector followed by the growth of automobile industry, two-wheeler industry and Hero Honda Motors Limited

Determine the apparent range of the target - radar system, Consider radar w...

Consider radar with a PRF of 5 kHz. What is the maximum unambiguous range R ua of this radar, in km?  If a target is located at a range of 50 miles, how many pulses will the r

Determine the maximum hoop - conical shells, Determine the maximum hoop: ...

Determine the maximum hoop: A conical water tank of height 2 metres & base radius 500 mm is supported at top and is full of water. The thickness of the wall is refer to 24 mm,

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd