Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Legal aspects of entrepreneurship development , Legal Aspect :  Few simple ...

Legal Aspect :  Few simple steps to take care of legal aspects of setting up a business are to register your unit with concerned organisation, check out the labour laws that would

Evaluate total extraction, Evaluate total extraction: The steel tie r...

Evaluate total extraction: The steel tie rod 50mm in diameter and 2.5m long is subjected to pull of 100 KN . To what length the rod must be bored centrally so that total ext

Estimate the horizontal at equilibrium angel, (Rigid body acceleration) A ...

(Rigid body acceleration) A tank of water accelerates down an icy frictionless ramp of angle . What angle ( ) does the water make with the horizontal at equilibrium?

What is a cotter joint, These parts of joints are used to connect two rods,...

These parts of joints are used to connect two rods, which are under compressive or tensile stress. The ends of the rods are in the manner of a socket and shaft that fit together an

Plant layout optimization, How to do matlab coding for computerized relativ...

How to do matlab coding for computerized relative allocation of facilities technique

Automation material specifications, Q. Automation Material Specifications? ...

Q. Automation Material Specifications? Automation Material Specifications include the development and / or review of material specifications, and the review of data sheets, mat

Thermodynamics, About zeroth law of thermodynamics

About zeroth law of thermodynamics

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd