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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Sentiment analysis is a subfield of NLP concerned with the determination of opinion and subjectivity in a text, which has application in the analysis of online product reviews, rec
state and prove varigan theorm?
Q. A wooden beam of the rectangular cross section is subjected to bending moment of 5KNm. If the depth of section is to be double the breadth and stress in wood is not to exceed 6
What do you mean by synchromesh device ? explain the basic working of a synchromesh gear box.
basics of static balancing.
Find out the maximum deflection in beam: A beam of span 8m is loaded with UDL of 10 kN/m over the middle half portion. Discover the maximum deflection. EI is constant. Sol
design criteria for chain drives
The corrosion resistance of the austenitic stainless steels (within the concentration and temperature conditions described above) relies on the formation and stability of a passive
advantages of proell governor
What is Time-Study ? How the standard time is determined in Time-Study ? What are the Merit-Rating ? Illustrate various methods of Merit-Rating. Describe the Break-Even-Analy
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