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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Calculate Drilling Speed and Machining Time Calculate the drilling speed if a 50 mm dia hole of 60 mm depth is to be drilled in a M.S. component. The feed rate is 0.2652 and M
With the help of diagram , depict the evaluation of Machine Design. Discuss in detail Technical feasibility, finanacial and economic feasibility, social and environmental feasib
significance & relevance of lubrication
INTRODUCTION: Previously, you studied about the repairing some parts of a motorcycle. In this unit, we shall mainly emphasise on the troubleshooting of the basic problems. This un
Creep: Creep of rails is the forward movement of rails in the direction of dominant traffic over a period of time. Creep is undesirable because it disturbs the gauge of the t
A triangle ABC with vertices A (30,20), B(90,20), C(30,80) is to be scaled by a factor of 0.5 about a point X(50,40). Calculate :- (i) The composite transformation matrix; and
Give differences between direct stress and bending stress. Direct tensile and compressive stress is set up because of load applied parallel to length of object, and direct shea
Hi there could I please get a quote for the attached Electrical assignment please. Particular attention needs to be taken in terms of the instructions
Safety Functions - Industrial Safety In the statement about safety organization various functions have been mentioned. Yet, a clear description is lacking. Without much elabor
case study for factors affecting process design decisions
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