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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Solid Modeling: 3-D solid modelling techniques provide the user along with complete information regarding the model. These may be quickly created without having to describe in
Q. Vessels resting on concrete foundations? For vessels resting on concrete foundations, the allowable concrete bearing stress shall be 750 psi (5 MPa). The design loadings fo
dy/dx=e^x-y+x^2e^-y
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(a) A member ABC is formed by connecting a steel bar of 20mm diameter to an aluminium bar of 30 mm diameter, and is subjected to forces as shown in figure. Evaluate the total defor
is effective commucation an intergral aspect in the mechenical engineering field?
A Torsion dynamometer is used in a propeller shaft of a marine Engine. It is found that the shaft twists 2 o in a length of 20 meters at 120 r.p.m. If the shaft is hollow with 300
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what do you mean by compounding of turbine?explain pressure-velocity compounding with neat sketch.
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