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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Induction Pressure Welding In this process, the current is induced by high frequency induction process in the job. Due to electrical induction the job is heated. When a suitabl
which topics i should take from mechanical engineering to compare them
operation
A mechanical System (two degrees of freedom system) is represented by the following two differential equations: m1x"1+(k1+k2)x1-k2x2=0 m2x"2-k1x1+(k2+k3) x2=0 Given m1=m2=0.5kg, k
The tank can be modelled from first principles with the provision of certain assumptions. For the sake of simplicity, it is possible to consider the top section of the tank with p
Calculate the Actual Machining Time Estimate the actual machining time required for the component of diameter 42 mm and length 120 mm. The available speeds are 70, 110, 176, 2
At a sudden enlargement of a water main from 240 mm to 480 mm diameter, the hydraulic gradient rises by 10 mm. Estimate the rate of flow.
Illustrate with working, construction and measurement of brake power by Belt transmission type brake dynamometers? The essential features of a transmission dynamometer are show
Drill Bit: This is a drilling tool used in drilling machines. The application of this tool is to make holes. Figure shows drill bit. Figure: Drill Bit
Q. Give the expression for inductance of a ? N ? turn coil wound on a core having length I cross - sectional area A and magnetic permeability µ. Explain the significance of
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