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Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb" built from years of experience. A summary is provided below for a standard Stirred Tank Reactor (STR).
Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter or aspect ratio as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.
(a) Increasing height
i. increases the hydrostatic pressure
Advantage - increases solubility of oxygen
Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2 ii. allows more agitators
Advantage - better power development
Disadvantage - can lead to poor mixing due to compartmentalisation (b) Increasing diameter
i. lowers the superficial (linear) gas velocity
Disadvantage - poor mixing, oxygen transfer ii. reduces wall surface area (per unit volume) available for heat transfer
Disadvantage - leads to temperature control problems
Different types of information units of CAD There are different types of information units defined. They are : Class 0 The geometric primitives needed for describing 2- a
how should we consider positive or negative when summation of forces
what is the meant by kleins construction?
I need rewording
Butt joints- formed by placing the plates edge to edge and welding them. Grooves are sometimes cut (For thick plates) on the edges before welding. According to the shape of the gro
A cantilever truss is loaded and supported as shown in the figure given below. Find the out value of P , which would produce an axial force of magnitude 3KN in member AC .
Name The Boolean Set Operators used in CSG The Boolean Set Operators used are : union : A + B is the set of points that are in A or B. intersection : A . B is the s
Classification Two categories of plastics are identified. Those are: thermosetting plastics and thermoplastics. Plastics generally cannot stand higher temperatures. They becom
Consider fully developed laminar flow with constant properties in a circular tube. Let there be heat transfered to or from the fluid at a constant rate per unit of tube length.Ad
What is bending stress? The bending moment at section tends to bend or deflect beam and internal stresses resist its bending. The process of bending stops when the cross sectio
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