Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Explain the principal of resistance welding, Can you explain the principal ...

Can you explain the principal of resistance welding? Classify various Resistance welding processes and Illustrate in detail two of them. With the help of neat and clean graph ex

What are the advantages of compound compression, What are the advantages of...

What are the advantages of compound compression with intercooler over single stage compression? Explain with the help of schematic and P-h diagrams, the working of a two stage c

Determine moment of the force about the origin, (a) What do you understand ...

(a) What do you understand by couple moment. Is it a free vector ? (b) A force F = 10i + 6j - 6k N performs at a position (10, 3, 4) m relative to a coordinates system. Determin

Compound BArs, three vertical, parallel straight rods, each 2.6m in length ...

three vertical, parallel straight rods, each 2.6m in length have their upper ends firmly secured and their lower supporting a rigid horizontal bar with a weight of 8KN, which cause

What is the eutectoid composition, Question 1 What is the eutectoid com...

Question 1 What is the eutectoid composition in the phase diagram? Question 2 For an alloy of 40%C/60%D at 400°C, indicate the phase/s that are present. It is not neces

Define advantages of welding process, Advantages of welding process Wel...

Advantages of welding process Welding results in a good saving of material and reduced labour content of production. Low manufacturing costs. Dependability of the me

Express the force in vector form, Express the force in vector form: A ...

Express the force in vector form: A force of 400 N forms angles of 45 o , 65 o and 120 o , respectively, along with the x, y and z axes. Express the force in vector form.

Series spot welding, Series Spot Welding In series welding, a portion o...

Series Spot Welding In series welding, a portion of the secondary current by passes any weld nugget being formed. And This shunt current passes through one of the panels being

Compare two stroke with four stroke engine, Compare Two Stroke with four st...

Compare Two Stroke with four stroke Engine: T w o Stroke Engine In two stroke engine all the four operation that is suction, compression, ignition and exhaust are compl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd