Fermenter dimensions and mechanical design, Mechanical Engineering

Assignment Help:

Once the total volume of an individual vessel has been established the detailed dimensions or mechanical design can be performed. Much of this is based on "Rules of Thumb"  built from years of experience. A summary is provided below  for a standard Stirred Tank Reactor (STR). 

Perhaps the most important factor in the mechanical design of a bioreactor is the height to diameter  or aspect  ratio  as this determines many of the other important bioreactor characteristics. There are relative advantages of increasing either the height or diameter.

(a) Increasing height

i.  increases the hydrostatic pressure

Advantage - increases solubility of oxygen

Disadvantage - increases solubility of other gases which may be toxic, e.g. CO2
 
ii.  allows more agitators

Advantage - better power development

Disadvantage - can lead to poor mixing due to compartmentalisation
 
(b) Increasing diameter

i. lowers the superficial (linear) gas velocity

Disadvantage - poor mixing, oxygen transfer
 
ii. reduces wall surface area (per unit volume) available for heat transfer

Disadvantage - leads to temperature control problems


Related Discussions:- Fermenter dimensions and mechanical design

Thermodynamics, we can use in proove of energy is a propertyof system we ca...

we can use in proove of energy is a propertyof system we can use (E) instead of (dQ-dW)

Cad, nc & cnc machines

nc & cnc machines

Balsa wood truss car design, design a car to be build by balsa wood trusses...

design a car to be build by balsa wood trusses, the car has to be with in a specific dimension, calculations of forces on members and nodes using method of joints need to be done a

GOVERNOR, IN CASE OF WILSON HARTNELL GOVERNOR THERE TWO MAIN SPRINGS AND TH...

IN CASE OF WILSON HARTNELL GOVERNOR THERE TWO MAIN SPRINGS AND THERE ARE ONE AUXILIARY SPRING. AND NATURE OF SPRINGS ARE TENSION ALWAYS HOW IT CAN POSSIBLE? WHEN SLEEVE WILL MOVE D

Determine the reaction at specific points, Determine the reaction at specif...

Determine the reaction at specific points: A light rod AD can be supported by frictionless pegs at B and C and rests against frictionless wall at A as shown in th

Parts of aircraft - air transportation, Parts of Aircraft  The main p...

Parts of Aircraft  The main parts of an aircraft are (Figure): (a) Engine, which propels the aircraft; the aircraft may have jet engines or propeller driving engines. (b

Terms related to stream engine, Terms related to stream engine: STEA ...

Terms related to stream engine: STEA M ENGINE MAIN PARTS: 1 .     Frame: It supports the various moving parts. 2 .     Cylinder: It forms a chamber in which the

Angle of friction, Angle of friction:   It can be defined as t...

Angle of friction:   It can be defined as the angle made by resultant of normal reaction ( R ) and limiting force of friction ( F ) with normal reaction ( R ). Let,

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd