Explain the glomerular filtration rate (gfr), Science

Assignment Help:

Explain the Glomerular Filtration Rate (GFR)

The kidneys receive a large amount of blood flow. The kidney blood flow is approximately 1200 ml per minute. One-tenth of this is filtered as the blood flows through the glomeruli i.e., about 120 ml. Filtration takes place through the semi-permeable walls of the glomerular capillaries, which are almost inlpermeable to proteins and large molecules. The filtrate is thus virtually free of proteins and has no cellular elements. The glomerular filtrate is formed by squeezing the fluid through the glomerular capillary bed.

The driving hydrostatic pressure (the pressure exerted by a liquid as a result of its potential energy) is controlled by the afferent and efferent arterioles (the muscular walled vessels leading to and from each glomerulus, and is provided by the arterial pressure, that is, the pressure of the circulating blood on the arteries. The glomerular filtration rate decreases with age and disease. In order to keep the renal blood flow and GFR relatively constant, the hydrostatic pressure in the glomerulus has to be kept fairly constant. When there is a change in the arterial blood pressure, there is a constriction or dilatation of the afferent and efferent arterioles. This process is called as autoregulation and can be more precisely defined as the tendency of the blood flow to organ to remain constant in spite of the pressure changes in the artery that delivers blood to that organ.


Related Discussions:- Explain the glomerular filtration rate (gfr)

Zoology, general characters of cylintreta

general characters of cylintreta

Assingment, how to do assingment phylum annelida

how to do assingment phylum annelida

Matter, what is meaning of solid'' liguid'' gases?why eresers float in wate...

what is meaning of solid'' liguid'' gases?why eresers float in water?why deos paper sink in water?

Explain how to solve the evacuation route problem, You are the mayor of a b...

You are the mayor of a beautiful city by the ocean, and your city is connected to the mainland by a set of k bridges. Your city manager tells you that it is necessary to come up wi

Coping stress, Ask question #Minimum 100 words acceptedYou are caring for a...

Ask question #Minimum 100 words acceptedYou are caring for a 29-year-old woman who is married with two small children, ages 1 and 3 years, at home. She is recuperating from a left

Eutrophication, Eutrophication: Materials such as sewage or organic w...

Eutrophication: Materials such as sewage or organic wastes from milk plants, canneries, slaughter houses, paper mills, starch factories and fish processing plants, and runoff

Studying the main parts of a flower, Studying the main parts of a flower ...

Studying the main parts of a flower Examine specimens of large simple flowers such as "tulips or lilies". Count the stamens & observe how they well arranged about the central p

How are clouds formed?, Q.How are clouds formed? During day time, on bei...

Q.How are clouds formed? During day time, on being heated, a large amount of water evaporates from various water bodies and goes into the air. A part of this water vapour also r

Effects of global warming, Effects of Global warming ñ Alterations in ...

Effects of Global warming ñ Alterations in the Global Precipitation: A more warm atmosphere will contribute to enhanced evaporation from surface waters and leads to the more

Write a comprehensive mental state assessment , Linh has been brought by am...

Linh has been brought by ambulance to the Emergency Department of the local metropolitan hospital where you are working, following a drug overdose of thirty Paracetamol tablets whi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd