Explain the glomerular filtration rate (gfr), Science

Assignment Help:

Explain the Glomerular Filtration Rate (GFR)

The kidneys receive a large amount of blood flow. The kidney blood flow is approximately 1200 ml per minute. One-tenth of this is filtered as the blood flows through the glomeruli i.e., about 120 ml. Filtration takes place through the semi-permeable walls of the glomerular capillaries, which are almost inlpermeable to proteins and large molecules. The filtrate is thus virtually free of proteins and has no cellular elements. The glomerular filtrate is formed by squeezing the fluid through the glomerular capillary bed.

The driving hydrostatic pressure (the pressure exerted by a liquid as a result of its potential energy) is controlled by the afferent and efferent arterioles (the muscular walled vessels leading to and from each glomerulus, and is provided by the arterial pressure, that is, the pressure of the circulating blood on the arteries. The glomerular filtration rate decreases with age and disease. In order to keep the renal blood flow and GFR relatively constant, the hydrostatic pressure in the glomerulus has to be kept fairly constant. When there is a change in the arterial blood pressure, there is a constriction or dilatation of the afferent and efferent arterioles. This process is called as autoregulation and can be more precisely defined as the tendency of the blood flow to organ to remain constant in spite of the pressure changes in the artery that delivers blood to that organ.


Related Discussions:- Explain the glomerular filtration rate (gfr)

Cloud made of comets, A Cloud Made of Comets The cold outer areas bey...

A Cloud Made of Comets The cold outer areas beyond Pluto are the regions of  comets, those visitors that dash, around the Sun, seldom to be seen again. Comets are of grei3t

Explain sympathetic - nerves system, Explain Sympathetic - Nerves System ...

Explain Sympathetic - Nerves System Sympathetic, as the word suggests, means to sympathize. The body sympathizes during fight, flight and fright reaction. For example, have you

In how many groups proteins may be classified, Proteins  may  be  classi...

Proteins  may  be  classified  broadly  into three  groups: a) Simple proteins, b) Conjugated proteins, and c) Derived proteins.

Find the angle of incidence, a ray of light falls on a transparent slab of ...

a ray of light falls on a transparent slab of refractive index u.if the reflected and refracted rays are mutually perpendicular to each other,find the angle of incidence.

Define the sympathetic nervous system, Define the Sympathetic Nervous Syste...

Define the Sympathetic Nervous System The sympathetic component of the autonomic nervous system is concerned with in- creasing the level of arousal and energy expenditure - pri

Feudal society, The Feudal Society: The economic basis of  the feudal sy...

The Feudal Society: The economic basis of  the feudal system was land, and the village was its economic unit. The feudal economy was dependent on local agricultural production

Experiment of a hair hygrometer, A hair hygrometer This device will ena...

A hair hygrometer This device will enable you to read the relative humidity directly without the use of tables. Procure a few human hairs about 30 cm long. Free them from gr

Erkinson develpomental theory, Maureen is a 50 year old married mother of t...

Maureen is a 50 year old married mother of three school age children. She works part-time at the local bank as a teller. She is going through menopause and is finding it very annoy

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd