Explain the glomerular filtration rate (gfr), Science

Assignment Help:

Explain the Glomerular Filtration Rate (GFR)

The kidneys receive a large amount of blood flow. The kidney blood flow is approximately 1200 ml per minute. One-tenth of this is filtered as the blood flows through the glomeruli i.e., about 120 ml. Filtration takes place through the semi-permeable walls of the glomerular capillaries, which are almost inlpermeable to proteins and large molecules. The filtrate is thus virtually free of proteins and has no cellular elements. The glomerular filtrate is formed by squeezing the fluid through the glomerular capillary bed.

The driving hydrostatic pressure (the pressure exerted by a liquid as a result of its potential energy) is controlled by the afferent and efferent arterioles (the muscular walled vessels leading to and from each glomerulus, and is provided by the arterial pressure, that is, the pressure of the circulating blood on the arteries. The glomerular filtration rate decreases with age and disease. In order to keep the renal blood flow and GFR relatively constant, the hydrostatic pressure in the glomerulus has to be kept fairly constant. When there is a change in the arterial blood pressure, there is a constriction or dilatation of the afferent and efferent arterioles. This process is called as autoregulation and can be more precisely defined as the tendency of the blood flow to organ to remain constant in spite of the pressure changes in the artery that delivers blood to that organ.


Related Discussions:- Explain the glomerular filtration rate (gfr)

Renaissance (1440-1540), Renaissance (1440-1540): The Renaissance was a...

Renaissance (1440-1540): The Renaissance was a revolutionary movement. It marked a definite and deliberate break with the past.  It swept away the medieval forms of economy, of

Fingerprinting the stars, Fingerprinting the Stars: Astronomers use var...

Fingerprinting the Stars: Astronomers use various methods to measure the distances to stars. For determining the distances to nearby stars, the method of  stellar parallax  is

Poisonous and infectious substances , Poisonous and Infectious Substances :...

Poisonous and Infectious Substances : These are the substances liable to cause death or serious injuries to health, if swallowed or inhaled or allowed to come in contact with skin

#titleChild Care Centers in Colorado, What are the ratios allowed for three...

What are the ratios allowed for three year olds and Child Care Centers in Colorado and what is the citation of the rules that addresses ratios?

Explain the special examination of urine, Explain the Special Examination o...

Explain the Special Examination of Urine The special examination requires the determination of various chemical substances in the urine including amino acids, bile pigments and

Main steps involved during post-harvest handling produce, Q. List the main...

Q. List the main steps involved during post-harvest handling fresh produce? Main steps involved during post-harvest handling fresh produce are: Field processing: sorting, gr

Explain the parathyroid glands, Explain the Parathyroid Glands The para...

Explain the Parathyroid Glands The parathyroid and thyroid glands are neighbours in the neck. You would realize that parathyroid glands are the small glands that lie behind the

Contour lnes.., five charactrstic of the contour lines

five charactrstic of the contour lines

Explain increase in sound wave pressure through middle ear, Explain Increas...

Explain Increase in Sound Wave Pressure through Middle Ear There are certain factors which contribute to an approximately eighty-fold increase in sound wave pressure through mi

Integumentary system , _____ are often responsible for clogging pores and c...

_____ are often responsible for clogging pores and causing pimpiles

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd