Explain the glomerular filtration rate (gfr), Science

Assignment Help:

Explain the Glomerular Filtration Rate (GFR)

The kidneys receive a large amount of blood flow. The kidney blood flow is approximately 1200 ml per minute. One-tenth of this is filtered as the blood flows through the glomeruli i.e., about 120 ml. Filtration takes place through the semi-permeable walls of the glomerular capillaries, which are almost inlpermeable to proteins and large molecules. The filtrate is thus virtually free of proteins and has no cellular elements. The glomerular filtrate is formed by squeezing the fluid through the glomerular capillary bed.

The driving hydrostatic pressure (the pressure exerted by a liquid as a result of its potential energy) is controlled by the afferent and efferent arterioles (the muscular walled vessels leading to and from each glomerulus, and is provided by the arterial pressure, that is, the pressure of the circulating blood on the arteries. The glomerular filtration rate decreases with age and disease. In order to keep the renal blood flow and GFR relatively constant, the hydrostatic pressure in the glomerulus has to be kept fairly constant. When there is a change in the arterial blood pressure, there is a constriction or dilatation of the afferent and efferent arterioles. This process is called as autoregulation and can be more precisely defined as the tendency of the blood flow to organ to remain constant in spite of the pressure changes in the artery that delivers blood to that organ.


Related Discussions:- Explain the glomerular filtration rate (gfr)

Define contribution of eosinophils, Define Contribution of Eosinophils ...

Define Contribution of Eosinophils They are specifically equipped to deal with a lot of parasites (all helminth worms). The coating of helminthes and some complement components

Waves, Compare and contrast the characteristics of sound waves and electrom...

Compare and contrast the characteristics of sound waves and electromagnetic

Enumerate in brief about the earthworms, Enumerate in brief about the Earth...

Enumerate in brief about the Earthworms There are several species of earthworms, having slender cylindrical bodies with varying diameters. These organisms ingest the dead organ

Experiment of The buoyancy of water, The buoyancy of water Find a metal...

The buoyancy of water Find a metal can like a coffee can or a cigarette tin which has a tightly fitting cover. With the cover on, push the can into a pail of water, cover end d

Explain the urine creatinine test, Explain the Urine Creatinine Test Th...

Explain the Urine Creatinine Test This test measures the amount of creatinine in urine. A measurement of the serum creatinine level is often used to evaluate kidney function. U

Critique of articles on VTE, Due Date: May 15, 2016 23:59:59 Max Poin...

Due Date: May 15, 2016 23:59:59 Max Points: 150 Details: Prepare a critical analysis of a qualitative study focusing on the problem statement, study purpose, research questi

Healing touch of lasers, Healing Touch of Lasers: Contrast the above ...

Healing Touch of Lasers: Contrast the above application  of lasers with their uses in medicine where the laser is working wonders. A laser can be applied with almost perfect

Aprons for personal protective devices, Aprons : Additional protection, su...

Aprons : Additional protection, such as a rubber apron is recommended for work with appreciable amounts of chromic acid, hydrofluoric acid and other highly corrosive liquids.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd