Explain the glomerular filtration rate (gfr), Science

Assignment Help:

Explain the Glomerular Filtration Rate (GFR)

The kidneys receive a large amount of blood flow. The kidney blood flow is approximately 1200 ml per minute. One-tenth of this is filtered as the blood flows through the glomeruli i.e., about 120 ml. Filtration takes place through the semi-permeable walls of the glomerular capillaries, which are almost inlpermeable to proteins and large molecules. The filtrate is thus virtually free of proteins and has no cellular elements. The glomerular filtrate is formed by squeezing the fluid through the glomerular capillary bed.

The driving hydrostatic pressure (the pressure exerted by a liquid as a result of its potential energy) is controlled by the afferent and efferent arterioles (the muscular walled vessels leading to and from each glomerulus, and is provided by the arterial pressure, that is, the pressure of the circulating blood on the arteries. The glomerular filtration rate decreases with age and disease. In order to keep the renal blood flow and GFR relatively constant, the hydrostatic pressure in the glomerulus has to be kept fairly constant. When there is a change in the arterial blood pressure, there is a constriction or dilatation of the afferent and efferent arterioles. This process is called as autoregulation and can be more precisely defined as the tendency of the blood flow to organ to remain constant in spite of the pressure changes in the artery that delivers blood to that organ.


Related Discussions:- Explain the glomerular filtration rate (gfr)

Neuro, A physician notes that in a patient there is impaired vibration and ...

A physician notes that in a patient there is impaired vibration and position sense, astereognosis, and ataxia. The physician noted loss of all sensations in some areas of the patie

Media and scientific outlook in culture, Media and Scientific Outlook in Cu...

Media and Scientific Outlook in Culture: Apart from sharing of deeper values through history and continuous interaction,  the contribution made by  all sections of the people i

Experiment of lifting the water surface, Lifting the water surface Ben...

Lifting the water surface Bend the pointed end of a pin or use a piece of fine wire to make a hook. File the point of the hook unless it is very sharp. Put your eye on a level

#antabuse, The active ingredient in Antabuse, a drug used for the treatment...

The active ingredient in Antabuse, a drug used for the treatment of chronic alcoholism, is tetraethylthiuram disulfide, C10H20N2S4 (fw = 296.54). The sulfur in a 0.4329 g. sample o

Atmosphere, Atmosphere: Atmosphere is an envelope of the most useful ga...

Atmosphere: Atmosphere is an envelope of the most useful gases that cover the planet earth. It makes our planet unique and enables life to prosper. If  the earth did not have a

How is our atmosphere different from the atmospheres?, How is our atmospher...

How is our atmosphere different from the atmospheres on Venus and Mars? Earth's atmosphere is different from those of Venus and Mars. This difference lies essentially in their c

Psychology, What is the significance between sensory transduction and senso...

What is the significance between sensory transduction and sensory adaption?

Systems view of life, Systems view of life: Evolution has given rise to...

Systems view of life: Evolution has given rise to various types of  life forms from single celled bacteria to organisms as complex as a human being. It may interest you to know

Explain the filiform papillae, Explain the Filiform papillae These are ...

Explain the Filiform papillae These are long and slender and are the smallest of the three types of papillae. They are found to be most numerous on the edges and anterior two t

What is clay minerals, What is clay minerals The fraction of secondary ...

What is clay minerals The fraction of secondary minerals is often mixed with primary minerals and oxides of iron, aluminium and silicon and has a size of less than       0.002

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd