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Explain the Bioavailability of Vitamin E?
For dietary purposes, vitamin E activity is expressed as a-tocopherol equivalents (a-TEs). One α-TE is the activity of l mg α-tocopherol. To estimate the α-TE of a mixed diet containing natural forms of vitamin E, the number of milligrams of β-tocopherol should be multiplied by 0.5, y-tocopherol by 0.1, and a- tocopherols by 0.3. The bioavailability of tocopherols varies inversely with the uptake. This means that ingesting four times the amount of the vitamin raises tissue levels by only two-fold.
A high correlation exists between the total fat and tocopherol concentrations in blood serum. Thus, diseases associated with high serum lipids (hypothyroidism, diabetes, hypercholesterolemia) produce high plasma vitamin E levels and those associated to low serum lipids (abetalipoproteinemia-a genetic disorder that interferes with the normal absorption of fats and fat-soluble vitamins, malnutrition, cystic fibrosis) produce low vitamin E levels.
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dinstictive characteristics,classes of the kindom
Timing and number of doses It has been common practice to give antibiotics at the time of anesthesia induction, which results in adequate serum and tissue levels of the drugs;
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