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Explain The absorption of itraconazole capsules
It is decreased with concurrent use of drugs that reduce gastric acidity, such as antacids, H2-receptor blockers, proton pump inhibitors or didanosine (Videx).
Itraconazole is a potent inhibitor of the hepatic isozyme CYP3A4 and may enhances serum concentrations of drugs that are metabolized by this enzyme. For this reason, itraconazole is contraindicated with the following drugs: cisapride (Propulsid), dofetilide (Tikosyn), ergot alka- loids, levomethadyl (Orlaam), lovastatin, oral midazolam (Versed, and others), pimozide (Orap), quinidine, simvastatin, and triazolam (Halcion, and others). Itraconazole is itself also a substrate of CYP3A4; its metabolism may be affected by both inducers of the enzyme, such as rifampin and carbamazepine (Tegretol, and others), and by other inhibitors.
H y po c a l c a e m i a It is also known as milk fever or parturient paresis. The disease occurs due to imbalance in input and output of calcium and is characterize
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An account of characters of mollusca
As the heart rapidly slows during recovery from exercise, PVCs commonly occur and usually have no clinical significance. This may be a time when metabolic adjustments in the heart
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Shifting cultivation - Degradation of Ecosystem This method of cultivation is practised all over the globe, but is more prevalent in the tropical countries. In this practice a
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