Explain non-nucleoside reverse transcriptase inhibitors, Biology

Assignment Help:

Non-nucleoside reverse transcriptase inhibitors

(NNRTIs) - These drugs are direct, non-nucleoside inhibitors of HIV-1 reverse transcriptase. Combinations of an NNRTI with NRTIs tend to be at least additive in reducing HIV replication in vitro. HIV isolates that are resistant to NRTIs and protease inhibitors remain sensitive to NNRTIs, but cross-resistance is common within the NNRTI class. Resistance to NNRTIs develops rapidly if they are used alone or in combinations that do not completely suppress viral replication.

 


Related Discussions:- Explain non-nucleoside reverse transcriptase inhibitors

Indirect uses of biodiversity, The cost of replacing these indirect uses of...

The cost of replacing these indirect uses of biodiversity, even if it were technically possible, would be so high as to render it impossible to duplicate. We also do not know how

Osmotic function - essential elements, Osmotic Function - Essential Element...

Osmotic Function - Essential Elements Plant cells generally contain mineral ions 10 to 1000 times higher in concentration than the surrounding soil. That is why water enters t

Poultry and duck diseases-marek''s disease, Marek's disease Marek's dis...

Marek's disease Marek's disease is a lymphoproliferative disease of chicken, quails, bantams and other free-flying birds. It is caused by the Gallid Herpesvirus 2 of subfamily

Planning of nursing care - acute glomerulonephritis, Planning of Nursing Ca...

Planning of Nursing Care   Provide supportive and symptomatic treatment.  Provide bed rest.  Encourage diet restriction,  Implementation  of Nursing Care

Infective endocarditis, Infective Endocarditis   It  is a term used to ...

Infective Endocarditis   It  is a term used to include subacute bacterial endocarditis as well as infection caused by viruses  and fungi.  The causative organisms responsibl

Illustrate the technique of radiographic template, Technique of radiographi...

Technique of radiographic template 1. Block any severe interdental undercuts or spaces with wax. Soak the patient's diagnostic cast with wax up in slurry. (Slurry is the super

Transgenics considered a threat to the environmental safety, Q. Why are tra...

Q. Why are transgenics considered a threat to the environmental safety? The Transgenics can be dangerous to the whole biosphere since the transfer of genes between species may

Express the term - amnion, Express the term - Amnion One of the extraem...

Express the term - Amnion One of the extraembryonic membranes found in terrestrial vertebrate. The amnion is filled with fluid and the developing embryo of reptiles, birds, and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd