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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
OXIDATION OF PYRUVATE TO ACETYL CoA The oxidation of pyruvate to acetyl CoA is the irreversible route from glycolysis to the citric acid cycle. What is citric acid cycle?
Consequences of Aging It is hard to enumerate the general consequences of aging in different animals. Gradual loss of reproductive ability, neuromuscular coordination and not
State the terms complete alimentary tract, complete digestive tract and complete gut? A digestive tract which has an anal and oral opening. This adaptation allowed for a linear
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Advantage and disadvantages of Fensom and Spanner Electroosmotic Flow Hypothesis The model has several advantages over Munch's model. The presence of P- proteins, and the occl
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which is the molecular basis of inheritennce
Malignant catarrhal fever (MCF) Malignant catarrhal fever is invariably fatal generalized lymphoproliferative disease of cattle and sometimes of wild ruminants. It is common i
Define Standard titration - estimation of vitamin c in Chillies? Pipette 5 ml of standard ascorbic acid solution into a 100 ml conical flask. Fill the burette with the dye solu
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