Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Why are trees green, Why are trees green? It is because leaves have chl...

Why are trees green? It is because leaves have chloroplasts, which have a green pigment, which also have chlorophyll in them. They are used for conducting photosynthesis, which

Define the use of computers in numerical taxonomy, Define the Use of Comput...

Define the Use of Computers in Numerical Taxonomy The use of computers in numerical taxonomy has made it possible to compare a large number of characters from many organisms wi

Define management & prognosis of root perforation, Define Factors Affect Ma...

Define Factors Affect Management and Prognosis of Root Perforation Time Location of defect in relation of crestal bone Level of perforation Size Periodo

Explain the types of modified gellan gum, Explain the types of modified gel...

Explain the types of modified gellan gum There are 3 types of modified gellan gum.  (a) High acetyl gellan (partially deacetylated), which provides a thermo reversible gel,

Explain the transport of amino acids, Explain the Transport of Amino Acids?...

Explain the Transport of Amino Acids? More than one transport or carrier system functions in the absorption of amino acids. The active carrier system for neutral amino acids sh

Can you explain diabetes mellitus, Q. What is diabetes mellitus? Diabet...

Q. What is diabetes mellitus? Diabetes mellitus is the disease caused by action or deficient production of insulin and the consequent high blood glucose level and low glucose u

What is st elevation in leads without q-wave, Q. What is ST Elevation in Le...

Q. What is ST Elevation in Leads without Q-Wave? ST elevation in leads without Q-waves can occur in few very different situations, both of which are fairly uncommon. The first

Annelids - hormones in growth and reproduction, Annelids - Hormones in Grow...

Annelids - Hormones in Growth and Reproduction Studies on polychaetes have displayed that the endocrine glands play a key role in growth and reproduction. In addition to the b

Kingdom animalia, in what order did the shellfish belong? in what genus did...

in what order did the shellfish belong? in what genus did the shellfish belong? in what species did the shellfish belong?

Autotrophic and heterotrophic succession, Autotrophic and Heterotrophic Suc...

Autotrophic and Heterotrophic Succession The succession where initially the green plants are much greater in quantity than the animals, is known as autotrophic succession. Su

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd