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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
Composed of C, H and O (fewer polar OH bonds than carbohydrates) Can be used at energy storage, components of cell membranes, chemical signals & thermal insulation Are
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When a ventricQlar septa1 defect (VSD) is present, with no aortic stenosis, the peak velocitgr across the defect reflects the difference in pressure between the right ventricle an
name the sturcture formed when the male and female nuclei fuse during fertilisation.
• Blood cultures are critical in the diagnosis and management of IE. • Obtain blood cultures before starting antimicrobial therapy whenever possible. • Intravascular infection l
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Metabolism Metabolism as you know is a process by which living organisms acquire and use energy. A large number of biochemical reactions take place in the living organisms dur
classification of all organisms under d phylum protozoa
Stress - Responses of Plants to Stress Let us recall what happens within the natural communities occupying the same habitat. The relative location of two plants may place them
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