Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Determine what is dermal branchiae, Determine what is dermal branchiae? ...

Determine what is dermal branchiae? External extensions of outer epidermis and peritoneum of the echinoderm body cavity. Both outer epidermis and inner peritoneum are lined wit

Explain principle osazone test or phenylhydrazine reaction, Explain Princip...

Explain Principle Osazone Test or Phenylhydrazine Reaction? Phenylhydrazine reacts with carbonyl compounds in neutral or slightly acidic medium to give phenylhydrazones. These

Zoonotic diseases-japanese encephalitis, Japanese encephalitis Japanes...

Japanese encephalitis Japanese encephalitis (JE) is a mosquito-borne encephalitis and is caused by  flavivirus belonged to the family Flaviviridae. It is a zoonotic disease, i

X linked in the calico cat, A calico female has a litter of kitten which in...

A calico female has a litter of kitten which includes several calico females a yellow male a couple of yellow females and two black males what is the likely color of the father and

EMBRYOLOGY.., WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRY...

WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRYOLOGY

How do the repairing enzymes of the genetic system act, How do the repairin...

How do the repairing enzymes of the genetic system act? There are enzymes inside the cells that detect errors or alterations in DNA molecules and begin a repair of those errors

How plant use day-night length to solve the paradox, How plants use the pat...

How plants use the pattern of changes in day/night length to solve the paradox that day length is equal twice a year. Plants possess the ability to balance the daily changes in

Define hexokinase, Hexokinase, that catalyzes the first irreversible step o...

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up an

Evaluation of nursing process, Evaluation This is the last step in nur...

Evaluation This is the last step in nursing process. Throughout care, you constantly evaluate the progress the client has made towards reaching the pre-established goals/ ob

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd