Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Cleavage - development biology, Cleavage - Development Biology Cleavag...

Cleavage - Development Biology Cleavage or segmentation is a series of cell divisions of the fertilized .egg through which it is converted into a multicellular structure, call

Define reaction of fehling soxhlet method, Define Reaction of Fehling Soxhl...

Define Reaction of Fehling Soxhlet method? The reducing sugars formed are acted upon by the alkali of Fehling's solution to form enediols. These enediols are very unstable and

Specific causes of parental anxiety - hospitalization, Specific Causes of P...

Specific Causes of Parental Anxiety   Some of the factors  that increase  their anxiety include following:  1)  Fear of the strange environment in the hospital  2)  Fear

Effect of somatostatin for the pancreatic hormonal secretion, Q. What are t...

Q. What are the effects of somatostatin for the pancreatic hormonal secretion? Somatostatin inhibits both glucagon and insulin secretions.

What is malnutrition, What is malnutrition? Malnutrition can be defined...

What is malnutrition? Malnutrition can be defined as a pathological condition resulting from a relative or absolute deficiency or excess of one or more of the essential nutrien

Determine the organs of the digestive system of earthworms, Which are the c...

Which are the characteristics and organs of the digestive system of earthworms related to the type of diet of these animals? Earthworms eat decomposing organic material and sma

Describe the process of coronary atherosclerosis, Q. Describe the process o...

Q. Describe the process of coronary atherosclerosis? Atherosclerosis is an intimal disease of arteries ranging in size from the aorta to the epicardial coronary artery i.e. cha

Gastrulation, GAS T RUL A TIO N - Morphogenic movements are occure...

GAS T RUL A TIO N - Morphogenic movements are occured. 3 germinal layers are formed. Ectoderm, endoderm & mesoderm. Endoderm is formed first. Mesoderm is formed in the

Care of eyes, CAR E OF EYES - 1.       Eyes should be periodically exa...

CAR E OF EYES - 1.       Eyes should be periodically examined in children. 2.       While reading the paper should be held 36 cm. away from eyes and preferable at an angle

How to compare and contrast acids, Compare and contrast acids and bases in ...

Compare and contrast acids and bases in terms of their H+ ion and OH- ion concentrations.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd