Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

What is digital periapical radiography, Q. What is Digital periapical radio...

Q. What is Digital periapical radiography? Digital radiographs can be subjected to image processing with which the images can be altered to achieve task specific image characte

Protein synthesis, Protein Synthesis The central dogma of modern bioche...

Protein Synthesis The central dogma of modern biochemistry is totally based on the coded information holds within deoxyribonucleic acid (DNA). Double stranded DNA is converted

Explain the absence of passive fit of the prosthesis, Absence of Passive Fi...

Absence of Passive Fit of the Prosthesis A passive fit of the prosthesis reduces long term stresses in the superstructure, implant components and the bone adjacent to the impla

Bluetongue, B l u e t on g u e Bluetongue (BT) is a non-contagi...

B l u e t on g u e Bluetongue (BT) is a non-contagious and arboviral disease of both domestic and wild ruminants. The disease is enzootic in areas where reservoirs (cat

Circulatory system - blood vessels, BLOO D VESSELS - Some vessles s...

BLOO D VESSELS - Some vessles supply blood to wall of large vessels these are vessel of vessels or vasa vasorum . Mainly artery and vein, 2 types of vessels present.

Portal circulation, POR T AL CIRCULATION When a vein branches into se...

POR T AL CIRCULATION When a vein branches into set of capillary to distribute blood in some parts, such venous circulation is called portal system. Three types of portal syst

Tingling or numbness in hands - symptoms of diabetes, Tingling or numbness...

Tingling or numbness is seen in cases of neuropathy. It occurs gradually over time. As high sugar (glucose) in the blood damages the nervous system, particularly in the extremities

What is the vestibular system, What is the vestibular system? How does it o...

What is the vestibular system? How does it operate? The vestibular system is the part of the ear that participates in the control and regulation of the equilibrium of the body

Illustrate the major events of the final mitotic period, Q. What are the ma...

Q. What are the major events of the final mitotic period? The final mitotic phase is the telophase. In the telophase the following events occur decondensation of chromosomes ea

How hiv infection is mainly spread, It is mostly spread by sexual contact, ...

It is mostly spread by sexual contact, blood transfers and from HIV infected mother to child.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd