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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
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WORL D CONSERVATION STRATEGY PROPOSES THE FOLLOWING STEPS - 1. Preservation of critical habitats. 2. Protection of wild life in situ (in natural habitats) as we
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characters of phylum protozoa
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Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 Determine the Yersin
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