Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Define methods for studying the nutrient requirements, Define Methods for S...

Define Methods for Studying the Nutrient Requirements? 1) Population survey of nutrient intakes of healthy individuals is one method of estimating nutrient requirements. The av

What is normal bone physiology, What is normal bone physiology An insig...

What is normal bone physiology An insight into the normal bone physiology and its adaptation by modeling and remodelling process to functional stresses is also of importance. I

Deficiency diseases-copper deficiency, Copper deficiency Copper deficie...

Copper deficiency Copper deficiency may be primary or secondary (conditional). Primary copper deficiency occurs due to its inadequate dietary intake; whereas secondary copper d

Describe the complete transposition of great arteries, Describe the Complet...

Describe the Complete transposition of great arteries ? Lethal, relatively frequent malformation. Without treatment, it results in 30 per cent mortality within the first week o

Intergenic interactions, what are intergenic interactions ? please explain ...

what are intergenic interactions ? please explain with example of cross breeding. and how we calculate the phenotype and genotype. explain epistasis, duplicate genes, supplementary

Is a gene the same as a dna molecule, Q. Is a gene the same as a DNA molecu...

Q. Is a gene the same as a DNA molecule? Genes are units of heredity. A gene is a section or segment of a DNA molecule. This section of DNA provides a genetic code for synthesi

What are the risks of migration, What are the Risks of migration Eg ...

What are the Risks of migration Eg Getting lost (blown off course or similar) and the effect of this when there is a limited fuel supply. Insufficient food to build

Glucose-6-phosphate, Three molecules of ducose-6-phosphate  yield 3 molecul...

Three molecules of ducose-6-phosphate  yield 3 molecules of CO,  and 3 molecules of five carbon residues (pentose sugar). The latter are converted ultimately to  2 molecules  of  g

Define seminal plasma in human male, Seminal plasma in human males is rich ...

Seminal plasma in human males is rich in : 1. fructose and calcium 2. glucose and calcium 3. DNA and testosterone 4. ribose and potassium Fructose and Calcium

Cobalt (co) - micronutrients, Cobalt (Co) - Micronutrients The Co conc...

Cobalt (Co) - Micronutrients The Co concentration in the dry matter of plants grown in soil normally lies around 0.02 to 0.5 ppm. In soils the content varies from 1 to 40 ppm.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd