Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Chemoreceptors, Chemoreceptors These are receptors included in percept...

Chemoreceptors These are receptors included in perception of chemical stimuli. You will see that there are three kinds of Chemoreceptors among metazoans:  i) Those concerne

Explain sexual reproduction, Explain Sexual Reproduction ? In most hig...

Explain Sexual Reproduction ? In most higher organisms, replication occurs by sexual reproduction. Sexual reproduction begins with a process called meiosis. The products of me

What are the corals, Q What are the corals? Corals are characterized by...

Q What are the corals? Corals are characterized by their polypoid shape, slow growth and sessility and secretion of a solid skeleton made of calcium carbonate. Numerous coral i

Metabolism, What is Metabolism ?  The  sum total of vital activities ( ...

What is Metabolism ?  The  sum total of vital activities ( movements , nutrition, growth, respiration, excretion , reproduction, behaviour ,etc.  Is the  life  of a living  bei

Define bioactive substances from protein foods, Define Bioactive Substances...

Define Bioactive Substances from Protein Foods? Bioactive substances are derived from living organisms that can be used by humans for a variety of applications. They are consti

What is signal transduction, Signal transduction occurs when an extracellul...

Signal transduction occurs when an extracellular signaling molecule activates a cell surface receptor. In words, this receptor change intracellular molecules changes a response. Th

Inhibition might contribute to tumor formation, We now understand that muta...

We now understand that mutations that cause the inhibition of apoptosis are found in tumors. Because proliferation itself is not induced by the inhibition of apoptosis, explain how

Sulphur (s) - macronutrients, Sulphur (S) - Macronutrients Sulphur is ...

Sulphur (S) - Macronutrients Sulphur is present in the soil in inorganic and organic forms. In most soils organically bounds is the major S reservoir. The inorganic forms of S

Abscission - effects of plant growth regulators, Abscission - Effects of Pl...

Abscission - Effects of Plant Growth Regulators Abscission of leaves and fruit is one of the more obvious characteristics of senescence. Leaves do not fall simply because they

Structure and fate of endosperm, Structure and Fate of Endosperm The ...

Structure and Fate of Endosperm The cells of endosperm are usually thin-walled, large isodiametric and devoid of pits and store large amount of food materials. The starch alo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd