Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

What does myeloid immunodeficiency cause, Myeloid immunodeficiency causes p...

Myeloid immunodeficiency causes phagocytic function, which is impaired. Those who are affected with this will undergo with enhance in susceptibility to bacterial infection.

What is the meaning of trocophore, What is the meaning of Trocophore? T...

What is the meaning of Trocophore? This free-swimming ciliated larval stage is found in numerous animal phyla including Mollusca and Annelida. Larvae has a unique circle of pre

Geotropism - root and shoot morphogenesis, Geotropism - Root and Shoot Morp...

Geotropism - Root and Shoot Morphogenesis Roots always grow towards gravity. The lot threshold of geotropic response requires as little time as one minute Gravity pulls auxin

Hiatus hernia, Hiatus Hernia: In  this type of hernia, cardiac end of ...

Hiatus Hernia: In  this type of hernia, cardiac end of  the stomach passes through an abnormally wide oesophageal opening in the diaphragm  (see Fig. 2.6). Clinical manifestat

EMBRYOLOGY.., WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRY...

WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRYOLOGY

Define common complications with spinal trauma patients, Define Common comp...

Define Common complications with spinal trauma patients? Common complications with spinal trauma patients include pressure sores or decubitus ulcers, hypercalciuria and renal s

Set them up using the punnett square, Two gene loci, A and B, assort indepe...

Two gene loci, A and B, assort independently, and alleles A and B are dominant over alleles a and b. Indicate the probability of producing: An aB phenotype from a cross AaBb x AaBB

Precautions for detection of number of bacteria in milk, Explain the Precau...

Explain the Precautions for Detection of Number of Bacteria in Milk? 1. Make a thin film of milk on the slide. 2. Do not over stain with methylene blue.  If over staining ha

Define amino acids in the building blocks of proteins, Define Amino Acids i...

Define Amino Acids in the Building Blocks of Proteins? Amino acids, as you have already illustrated, have a carboxyl group and an amino group bonded to a common carbon atom and

Procaryotic structure and diversity, Procaryotic Structure and Diversity ...

Procaryotic Structure and Diversity The first organisms which did not have well defined nucleus, called procaryotes, (pro = earlier, caryon = nucleus) were probably anaerobic a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd