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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
Chambers of the Heart The heart is divided into two halves by a muscular wall or septum, the right heart and the left heart. The function of the right heart is to collect
Cold Chain System Vaccines are sensitive to heat. On exposure to heat their potency is lost. Once a vaccine has lost its potency it cannot be regained, so it is important
What is sustainable agriculture? Describe the contribution of biopesticides and biofertilisers in sustainable agriculture.
Define Physiological effects on the GIT of prebiotics? Since prebiotics are fermented by the gut microflora, they may have physiological effects on the GIT such as: Cont
economic importance
In mountain rabbits, the EL-1 gene is located on chromosome 3. Four alleles of this gene have been identified in the population. With respect to EL-1, what is the maximum number of
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Why are some types of hemorrhagic diseases caused by genetic or acquired deficiency of the vitamin K metabolism? Lack of vitamin K predisposes to hemorrhages as this vitamin i
Explain the Bulimia Nervosa? Diagnostic Criteria Bulimia Nervosa patients, unlike those of anorexia nervosa with binge and purge subtype, are typically within the normal weight
Define hydrolytic rancidity Lipolysis is a major action occurring during deep fat frying due to large amounts of water introduced from the food and the relatively high temperat
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