Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Pericardium, The heart is enclosed in a membranous sac called the pericardi...

The heart is enclosed in a membranous sac called the pericardium. It has two layers- the fibrous pericardium which is the outer layer and the serous pericardium that lies inside th

Systemic diseases in animals, S y s te m i c Diseases Diseases o...

S y s te m i c Diseases Diseases of the gastrointestinal tract The diseases of gastrointestinal system are manifested by abnormality in prehension, mastication and s

Conditions associated with increased need for vitamin a, Define Conditions ...

Define Conditions associated with increased need for Vitamin A? Conditions and populations associated with increased need for vitamin A includes young children  particularly  t

Find out the degrees of freedom, -The expected phenotypic ratio of offsprin...

-The expected phenotypic ratio of offspring. -The expected genotypic ratio of offspring. -Calculate the expected values you would use on a chi-square test (use genotypic rati

Explain precautions for preparation of bacterial smear, Explain Precautions...

Explain Precautions for Preparation of Bacterial Smear? 1. Plates used should be prepared 24 hours before use to avoid spreading of colonies due to moisture in plates. 2. Sw

Define dietary habits factor for obesity, Define Dietary habits factor for ...

Define Dietary habits factor for obesity? You are aware that a positive energy balance is one of the major contributory factors for obesity. Some people are in the habit of eat

Codominance, CODOMINANCE The alleles which do not show dominance-recess...

CODOMINANCE The alleles which do not show dominance-recessive relationship and are able to express themselves independently when present together are called codominant alleles.

Ciliary and flagellar movements, Normal 0 false false false...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Vitamin - a, VITAMIN - A Discovered by Macollum. Also known as ...

VITAMIN - A Discovered by Macollum. Also known as Retinol / Antixeropthalmic vitamin / Auxerophthol. It is vitamin for normal vision. It forms retinal pigments rho

Sweating - temperature relations in animals, Normal 0 false f...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd