Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Explain capillaries of the vascular system, Q. What are the capillaries of ...

Q. What are the capillaries of the vascular system? Capillaries are small blood vessels that perform exchange of substances between the tissues and blood the body Capillaries a

Pathophysiology of tricuspid regurgitation, Q. Pathophysiology of Tricuspid...

Q. Pathophysiology of Tricuspid regurgitation? Tricuspid regurgitation is associated with prominent venous filling waves and elevated right atrial venous pressures. Hepatic and

Social Determinants of Health, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What concentration of sucrose solution should administered, The volume of M...

The volume of Mrs. X's plasma was 3 liters before Ed administered the IV. Assume that there was a complete mixing of the administered water with her plasma but no mixing with her i

Immediate post-operative care to a cardiac patient, Immediate Post-operativ...

Immediate Post-operative Care The patient is accompanied to the ICU by a surgeon, anesthetist and the nurse who assisted for the surgery with portable ventilator and ECG

Explain lateral meristem, Which one of the following is not a lateral meris...

Which one of the following is not a lateral meristem? 1. Intrafascicular cambium 2. Interfascicular cambium 3. Phellogen 4. Intercalary meristem   Intercalary m

Of which main compounds is the mitochondrion structure made, Of which main ...

Of which main compounds is the mitochondrion structure made? Mitochondria are organelles delimited by two lipid membranes. The inner membrane invaginates to the interior of the

Explain the the use of soy protein in food industry, The use of soy protein...

The use of soy protein concentrates in different applications in food industry is highlighted herewith. a. Bakery products Unlesss higher protein fortification leve

Denitrification - nutrient cycles, Denitrification - Nutrient Cycles N...

Denitrification - Nutrient Cycles Nitrates are readily leached from the soil and also lost through denitrification the process by which molecular or gaseous nitrogen (N 2 ) as

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd