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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
DE A T H - It is terminal end of the degeneration changes of old age. Death occurs when vescular system & respiratory system stop working. Failure of nervous system ma
Explain what is DNA? DNA : DNA is the source of the information that directs the development of the cell. Although all segments of DNA are not active in every cell in the huma
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Propane boils at -46oC. Propanol boils at 97oC. The difference is attributable to- Select one: a. The fact that propanol is much heavier b. The fact that propanol ionizes all
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An osteoclast is a type of bone cell that absorbs bone tissue by removing its mineralized matrix and breaking up the organic bone. This process is known as bone resorption
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Emphysema Emphysema is destructive changes in alveolar walls and enlargement of air spaces distal to the terminal non-respiratory bronchioles. It is characterized physiolog
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