Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Adaptation, Adaptation is the tendency of an organism to suit its environm...

Adaptation is the tendency of an organism to suit its environment; one of the main points of Charles Darwin's theory of evolution by the natural selection: organisms adapt to thei

Captive breeding - measures for species conservation, Captive Breeding - Me...

Captive Breeding - Measures for Species Conservation Species which are reduced to dangerous levels need more intensive management, and one strategy is their captive breeding.

Type of disease identified chromosomes present in karyotype, Which type of ...

Which type of genetic disease can be identified from the visual analysis of the number of chromosomes present in a karyotype? The counting and the identification of chromosomes

Clotting disorder - haemophilia, Clotting Disorder - Haemophilia Haemo...

Clotting Disorder - Haemophilia Haemophilia  is a congenital  blood clotting  disorder caused by the genetic lack/ deficiency of  coagulation factor VIII or antihaemophiliac

Gastrulation, Gastrulation  Gastrulation is the process through whic...

Gastrulation  Gastrulation is the process through which the presumptive areas of organ specific rudimetns present on the surface of blastula move to their specific position

Cytokinesis in an animal cell, Cytokinesis in an animal cell: Splitting...

Cytokinesis in an animal cell: Splitting of the cell is called cytokinesis which starts at telophase. In animal cells, microtubules form a furrow in a ring around the cell.

Explain right atrial enlargement, Q. Explain Right Atrial Enlargement ? ...

Q. Explain Right Atrial Enlargement ? The right atrium (RA) is a globular chamber, forming the right heart border on the PA view. On the PA view, the border of the enlarged RA

What are the respective constituents of the gray matter, What are the respe...

What are the respective constituents of the gray matter and of the white matter of the spinal cord? The gray matter, or gray substance, of the spinal cord having predominantly

Explain restriction endonucleases are enzymes, Restriction endonucleases ar...

Restriction endonucleases are enzymes which: 1. make cuts at specific positions within the DNA molecule 2. recognize a specific nucleotide sequence for binding of DNA ligase

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd