Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

What are the major natural plant hormones and their effect, What are the ma...

What are the major natural plant hormones and what are their respective effects? The major natural plant hormones and their respective functions are the following- Auxins that

Explain separation of homologous chromosomes, Q. What are the respective fu...

Q. What are the respective functions of the separation of homologous chromosomes and of the separation of alike chromatids in meiosis? The separation of homologous chromosomes

What is metagenesis, What is metagenesis? What are the other names of this ...

What is metagenesis? What are the other names of this process? Metagenesis is the type of life cycle in which there are two dissimilar forms of individuals of the same species,

Define the risk reduction in cardiovascular disease, Q. Define the Risk red...

Q. Define the Risk reduction in cardiovascular disease? Ans. Weight loss by caloric restriction diets has been shown to decrease plasma CRP levels. Additional data indicat

Complications of making a definite classification, Assume for this question...

Assume for this question that we are discussing a rare human disorder. Describe as detailed as possible the characteristics of this disorder if it is: autosomal dominant autosomal

Fundamental polymers of life, The synthesis of the three fundamental polyme...

The synthesis of the three fundamental polymers of life, DNA, RNA and protein, is template-directed. This means that - Answer A. the monomers are assembled one by one in a sequence

First stage of invagination, First Stage of Invagination The large en...

First Stage of Invagination The large endodermal cells that are remaining in the vegetal plate move laterally towards the centre of the plate and fill the gap in the vegetal

Define fats requirements of school children and adolescents, Define Fats re...

Define Fats requirements of school children and adolescents? The linoleic acid requirements for school children and adolescents have been set at 3 en%. In terms of visible fats

What is a population, Q. What is a population? In the Biology a populat...

Q. What is a population? In the Biology a population is a set of individuals of the same species living in a given place and in a given time.

Explain the estimated average intake (ear), Explain The Estimated Average I...

Explain The Estimated Average Intake (EAR)? Considering that the nutrient requirements follow a normal distribution, the EAR is defined as 'the median usual intake that meets t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd