Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

What is non specific defence, What is Non specific defence Non specifi...

What is Non specific defence Non specifi c:  These relate to  the  physical barriers  like  skin  and mucous membrane. They form the first line of defence against entry of mic

Diseases of cardiovascular and haemopoietic system, D i s e a s e s ...

D i s e a s e s of Cardiovascular and Haemopoietic System Cardiovascular system maintains circulation of blood for normal exchange of fluid, electrolytes, oxygen and nut

How do you prevent food borne infection, How do you prevent food borne infe...

How do you prevent food borne infection? Prevention of Food borne infections: Avoid consumption of contaminated foods and water Eat properly cooked foods Wash

Point out some guidelines for breast-feeding, Point out some Guidelines for...

Point out some Guidelines for breast-feeding? 1) Follow demand feeding of the baby instead of a fixed schedule. 2) Initiate breast-feeding within 2 h after a normal delivery

What are primary consumers, What are primary consumers? Can a food chain pr...

What are primary consumers? Can a food chain present quaternary consumers without having secondary or tertiary consumers? Can a tertiary consumer of one chain be a primary or secon

Harshey-chase experiement, What is the Harshey-chase experiement .explain i...

What is the Harshey-chase experiement .explain in detail

Round worm, parasitic adaptation of round worm

parasitic adaptation of round worm

Lamarckism theory of organic evolution, THEORY OF ORGANIC EVOLUTION - ...

THEORY OF ORGANIC EVOLUTION - LAMARCKISM Theory of the inheritance of acquired characters or Lamarckism put forwarded by Jean Baptist de Lamarck (1809) in his book "

Charles darwin was the first person, Charles Darwin was the first person to...

Charles Darwin was the first person to suggest that: a. the present forms of all existing species are the result of natural selection b. species have changed over long periods of t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd