Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Sp and spp., what is the deference between sp. and spp.?

what is the deference between sp. and spp.?

What are protein hydrolysates, What are protein hydrolysates? Proteins ...

What are protein hydrolysates? Proteins that have been treated with enzymes to break them down into amino acids or shorter peptides are referred to as protein hydrolysates.

Medical therapy for tricuspid stenosis, Q. Medical therapy for tricuspid st...

Q. Medical therapy for tricuspid stenosis? Medical therapy is ineffective. With diuretics, symptoms of congestion are replaced by that of low cardiac output state. Occasional c

What is herbicide tolerant crops in evolutionary, Evolutionary ...

Evolutionary Herbicide tolerant crops (HTC) Increased use of herbicide can result in increase in development of weed resistance to that herbicide either through

Ecosystem influence the biological diversity, Q. How does the vegetal strat...

Q. How does the vegetal stratification of an ecosystem influence the biological diversity? The vegetal stratification of the ecosystem like the strata of the Amazon Rainforest,

Which starch is being broken down by an enzyme, In an investigation to comp...

In an investigation to compare the rates at which starch is being broken down by an enzyme    (a) what test is used    (b) how do you know when the reaction

Legal level -pollution control, Legal level -Pollution control Polluti...

Legal level -Pollution control Pollution must be controlled by effective legislation also. Like USA, Japan, Germany and many other countries a comprehensive legislation for pr

Post-mating isolating mechanisms, The second category of isolating mechanis...

The second category of isolating mechanism that may permit interspecific mating but ensures reduced viability is called post-mating isolating mechanism. This category could be subd

Impoundments - lentic ecosystems, Impoundments - Lentic Ecosystems We...

Impoundments - Lentic Ecosystems We have so far discussed natural lakes. In addition to these there are a number of lakes both small and large artificially created by man cal

What is eutrophication in ecology explain briefly, What is Eutrophication i...

What is Eutrophication in ecology explain briefly? Freshwater ecosystems demonstrate the close relationship between aquatic and terrestrial ecosystems. Until recently, most peo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd