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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
What are algal blooms
Phylum Sarcomastigophora Locomotory organelles - flagella, pseudopodia or both types, usually with one type of nucleus; typically no spore formation, sexual reproduction thro
Define Rheology and syneresis Rheology: the science of the deformation and flow of matter. It is the branch of physics concerned with the flow and change of shape of matter,
In the eukaryote cell nucleus, RNA can be found dispersed in the nuclear fluid, along with DNA, and as the major constituent of the nucleolus. In cytosol (in eukaryotes or in bacte
Q. Define Hepatic Cholesterol Synthesis? This is a highly complex process beginning with acetyl CoA formed from fatty acid oxidation or from carbohydrate breakdown. The rate-de
Define Carcinogenic - Dietary Factors? Dietary constituents can also be carcinogenic. But to what extent diet is one of the contributing factors to cancer development is not kn
Explain Adverse Effects of ketoconazole Anorexia, nausea and vomiting are common with higher doses (>400 mg/day) of ketoconazole; taking the drug with food or at bedtime may i
RNA editing is the name given to several reactions whereby the nucleotide series on an mRNA molecule should be modified by mechanisms other than RNA splicing. T
how autophagy help in converting a tadpole larva into adult amphibian
Name two ways in which the chances of hypothermia can be reduced during outdoor activities. Eating well before going out and wearing warm, wind-proof clothing can reduces the c
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