Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Representatives of the echinoderm phylum, Q. What are some representatives ...

Q. What are some representatives of the echinoderm phylum? Starfishes, sea urchins, sea cucumbers (holothurians) and brittle stars are examples of echinoderms.

Determine minerals requirements at high altitude, Determine Minerals Requir...

Determine Minerals Requirements at high altitude? Increased urinary excretion of Nat and K + on exposure to hypoxia is reported while some workers have found only increase in

What is the phellogen? what its function, What is the phellogen? What its f...

What is the phellogen? What its function? The Phellogen also called as cork cambium is the meristematic plant tissue responsible for the formation of the periderm (the covering

Explain negative staining technique, Explain Negative Staining Technique? ...

Explain Negative Staining Technique? Here, a stain has a negatively charged chromophore that is repelled by the negative bacterial surface. It results in indirect staining of m

Prevention and control from escherichia coli, Q. Prevention and Control fro...

Q. Prevention and Control from escherichia coli? Prevention and Control: Involves avoiding contaminated food and water that have high coliform counts, avoiding unpasteurized ju

How shigellosis diseases occur in humans, How shigellosis diseases occur in...

How shigellosis diseases occur in humans Occurrence: Poor personal hygiene is a  common factor in food borne shigellosis, with shellfish, fruits and vegetables, chicken and sal

Effects of long term malnutrition on children, Effects of long term malnutr...

Effects of long term malnutrition on children The effects of long time malnutrition are more severe in children. Unlike adults children do not have sufficient amounts of c

Skin, what is the warmest and coldest parts of the boy

what is the warmest and coldest parts of the boy

What is the importance of vitamin D, Importance of vitamin D Vitamin D ...

Importance of vitamin D Vitamin D is mainly involved in the  calcium and phosphate metabolism. It usually promotes absorption of calcium and inorganic phosphate from the intest

Blank titration for determination of iodine number of lipids, Define Blank ...

Define Blank titration for Determination of the Iodine Number of Lipids? Using an autopipette, measure 25 ml of Hanus iodine reagent accurately and transfer into a 250 ml iodin

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd