Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Problems with untreated/ammoniated crop residues, Problems with untreated/a...

Problems with untreated/ammoniated crop residues Besides the low energy and protein contents, crop residues generally contain low content of minerals such as Calcium, Phosphor

What are the plant cell vacuoles, Q. What are the plant cell vacuoles? And ...

Q. What are the plant cell vacuoles? And what are their functions? And what is the covering membrane of the vacuoles called? Plant cell vacuoles are cell structures delimited b

Functions of kidney, FUNCTION S OF KIDNEY - 1.      Excretion of nitro...

FUNCTION S OF KIDNEY - 1.      Excretion of nitrogenous wastes. 2.      Maintenance of water balance or osmoregulation. 3.      Acid base balance or regulation of pH.

Why red-green colour blindness is x-linked recessive, Red-green colour blin...

Red-green colour blindness is X-linked recessive. A woman with normal colour vision has a father who is red-green colour-blind. The woman has four sons, none of whom are colour-bli

How is carbon dioxide released by cellular respiration, Q. How is carbon di...

Q. How is carbon dioxide released by cellular respiration transported from the tissues to be eliminated through the lungs? In vertebrates almost 70% of the carbon dioxide is ca

Scintillation counter, carnt understand its principle and mode of working

carnt understand its principle and mode of working

Phloem, why phloem made of living cells

why phloem made of living cells

Smooth muscles, Normal 0 false false false EN-IN X-NO...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Difference between translation and transcription, Q. What is the difference...

Q. What is the difference between translation and transcription? Transcription is the name given to the formation of DNA molecules from an open DNA chain used as a template, Tr

Explain advantages of having internal gills, 1. Explain the challenges and ...

1. Explain the challenges and advantages of having internal gills over external gills for gas exchange? 2. Explain how increased stress levels can affect hormones which ultimate

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd