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Explain Nephrotoxicity
Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus (Prograf) and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.
What is Prostetic group Prostetic group :- A non-protein part of the enzyme which remains tightly bound to the protein part.
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How does the intensity of simple diffusion differ in relation to the concentration gradient of the moved substance? The higher the concentration gradient of a substance the ext
Define Role of Glucose-6-phosphate dehydrogenase - Gene Expression? Glucose-6-phosphate dehydrogenase (G6PD) is another enzyme involved in lipogenesis that is regulated by diet
extensive note on the excretory system of amphibian
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Progress on these biological issues needs both that more mathematics and statistics be brought to bear on them and that new mathematical and statistical tools be prepared. All the
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