Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Isomerisms types of unsaturated fatty acids, Unsaturated fatty acids show ...

Unsaturated fatty acids show different types of  isomerisms. We have already learnt about the.concept of  isomerism  in  the  last unit. You would  realize that fatty acids with s

Do enzymes act better under acid or basic ph, Do enzymes act better under a...

Do enzymes act better under acid or basic pH? Most enzymes act in pH among 6 and 8, a range that corresponds to the general acidic level of cells and blood. There are enzymes,

Explain glucocorticoids, Explain Glucocorticoids The adrenal cortex se...

Explain Glucocorticoids The adrenal cortex secretes the glucocorticoids which  increase gluconeogenesis by increasing hepatic intake of amino acids accompanied by increased ac

How do embryos of placental mammals excrete nitrogen wastes, Q. How do embr...

Q. How do embryos of placental mammals excrete nitrogen wastes? Placental animals including embryos and excrete urea, In the adult placental mammal urea is excreted through the

What is megalobastic anemia, Question 1) What is megalobastic anemia? Disc...

Question 1) What is megalobastic anemia? Discuss briefly its lab diagnosis. How would you differentiate megaloblastic anemia from other anemias? Question 2) What is hem

Group selection, The effect of natural selection on colonies or population ...

The effect of natural selection on colonies or population favouring one group in preference to other may be referred to as group selection. A group can be the smallest collection o

Abscisic acid (aba) - plant growth substances, Abscisic Acid (AbA) - Plant ...

Abscisic Acid (AbA) - Plant Growth Substances In 1961 Lice and Cams isolated a substance in crystalline form from mature cotton fruit. This substance stimulated the abscission

Genetics, What is pedigree analysis . How to solve the complicated question...

What is pedigree analysis . How to solve the complicated questions of pedigree . How to identify wheather it is dominant or reccessive its genotype

Biochemical and metabolic problems and their management, Define Biochemical...

Define Biochemical and Metabolic Problems and their Management? Hypokalaemia (low concentration of potassium ion in the blood), we learnt earlier, is a problem caused due to se

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd