Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Define rhizoids - types of hyphae, Define Rhizoids - Types of Hyphae? ...

Define Rhizoids - Types of Hyphae? Rhizoids - These are brown slender root like structures which arise in cluster from each node of the stolon. These penetrate the substratum

Why all specialization occurred during this time period, There is a lot of ...

There is a lot of dataset and hypothese that attempt to explain why there was a Cambrian Explosion. Using all supporting ideas, explain and write a paragraph on why all this specia

Why does the recombination frequency of genes vary, Why does the recombinat...

Why does the recombination frequency of genes vary with the distance between them in the chromosome? The farther the distance among the loci of two genes in a chromosome the hi

Benefits of high-throughput expression , What are the benefits of high-thro...

What are the benefits of high-throughput expression analysis in molecular biological investigations? Ans) These methods permits simultaneous analysis of the expression of a lot

What are the glucagon receptors in the plasma membranes, Which of the follo...

Which of the following serves as an effector, or as part of an effector, that functions in a negative feedback system? A. Glucagon Receptors in the plasma membranes of alpha-is

RNA synthesis, Distinguish features in the mechanisms of RNA synthesis, + (...

Distinguish features in the mechanisms of RNA synthesis, + (RNA), (-) RNA, and ds RNA viruses.

Determine the term - essential element, Determine the term - essential elem...

Determine the term - essential element It becomes difficult to meet all the conditions so as to establish essentiality. This is particularly so for the elements that are requir

Nursing management of myocarditis, Nursing Management Propped up po...

Nursing Management Propped up position.  Monitor signs and symptoms and laboratory test results documenting myocarditis.  Monitor adequacy of cardiac output and hemo

What are the components of mitral valve apparatus, Q. What are the Componen...

Q. What are the Components of mitral valve apparatus? 1) Annulus: Annulus is a saddle shaped structure with medial and lateral portions forming the basal points and anterior a

Explain the periapical surgery - endodontic surgery, Explain the Periapical...

Explain the Periapical surgery - Endodontic Surgery a) Curretage 1 b) Root-end ressection 2 c) Root-end preparation 3 d) Root-end filling 4

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd