Explain nephrotoxicity, Biology

Assignment Help:

Explain Nephrotoxicity

Nephrotoxicity is the major dose-limiting toxicity of amphotericin B deoxycholate; sodium loading with  normal saline may prevent or ameliorate it and is generally recommended for patients who can tolerate a fluid load. The nephrotoxicity of amphotericin B may add to the nephrotoxicity of other drugs including cyclosporine (Sandimmune, Neoral), tacrolimus  (Prograf)  and aminoglycoside antibiotics like gentamicin (Garamycin, and others). Hypo- kalemia and hypomagnesemia are common and are usually due to a mild renal tubular acidosis. Weight loss, malaise, anemia, thrombocytopenia and mild leukopenia can happen. Cardiac toxicity and myopathy have been reported.

 


Related Discussions:- Explain nephrotoxicity

Determine the term - essential element, Determine the term - essential elem...

Determine the term - essential element It becomes difficult to meet all the conditions so as to establish essentiality. This is particularly so for the elements that are requir

Define the disturbances in fluid balance, Define the Disturbances in Fluid ...

Define the Disturbances in Fluid Balance? The correct functioning of cells and tissues depends on appropriate concentrations of nutrients; so any abnormal loss or accumulation

Coagulation, which is the last enzyme in the thrombotic system?

which is the last enzyme in the thrombotic system?

Protozoa, What are the disadvantages of protozoa

What are the disadvantages of protozoa

Explain crossing over in genetics, Explain Crossing Over in genetics? C...

Explain Crossing Over in genetics? Crossing over is when the arms of homologous chromosomes exchange segments (and therefore genes) with each other. Recall that one of the homo

Class polychaeta - classification of coelom, Class Polychaeta - Classificat...

Class Polychaeta - Classification of Coelom There are mainly marine forms with distinct head, having eyes and tentacles, segments have lateral projections of the body wall ter

Primary egg envelopes, Primary Egg Envelopes These are the egg envelo...

Primary Egg Envelopes These are the egg envelopes which develop in the ovary between oocyte and follicle cells in the space occupied by the interdigitating microvilli. Such e

Explain about the various cooking methods, Explain about the various Cookin...

Explain about the various Cooking methods? All of us eat food either raw or in cooked form. Have you ever thought why we need to cook food?  Cooking is a primary process to mak

What is meant by substrates of enzymatic reactions, What is meant by substr...

What is meant by substrates of enzymatic reactions? Substrates are reagent molecules upon which enzymes act. The enzyme has spatial binding sites for the attachment of its s

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd