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Explain Lopinavir/ritonavir
Lopinavir is available in the US only in a fixed-dose combination with ritonavir . In treatment-naïve patients a regimen with lopinavir/ritonavir was more efficient than a nelfinavir-containing regimen. A regimen having lopinavir/ritonavir is a first choice in patients with previous HIV treatment and moderate or no protease inhibitor resistance (<5 resistance mutations).
Adverse Effects - Lopinavir/ritonavir is usually well tolerated. Mild diarrhea, nausea, headaches and asthenia have occurred.
Medical status of the patient Conditions like osteoporosis, history of radiotherapy, use of bisphosphonates which can affect the success of the treatment should be considered b
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