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Isobologram is a diagram used to characterize the interactions among jointly administered drugs or the chemicals. The contour of the constant response (that is the isobole), which is compared to the 'line of additivity', that is the line connecting the single drug doses which yield the level of response related with that contour. The interaction is described as the synergistic, additive, or an antagonistic according to whether the isobole is below, or coincident with, or above the line.
Described by the leading proponent as 'the conscientious, explicit, and judicious uses of present best evidence in making the decisions about the care of individual patients, and
Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic
Collector's problem : A problem which derives from the schemes in which packets of a particular brand of coffe, cereal etc., are sold with coupons, cards, or other tokens. There ar
explain the graphical method of measure of central tendency
An approach to investigations designed to recognize a particular medical condition in the large population, usually by means of a blood test, which might result in the considerable
Length-biased sampling : The bias which arises in the sampling scheme based on the visits of patient, when some individuals are more likely to be chosen than others simply because
Bivariate boxplot : A bivariate analogue of boxplot in which the inner area contains 50%of the data, and a 'fence' helps to identify the potential outliers. Robust methods or techn
O'Brien's two-sample tests are the extensions of the conventional tests for assessing the differences between treatment groups which take account of the possible heterogeneous nat
Difference between tretment design and experimental design
methods of measuring trend
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