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Explain Indications of Root-End Filling (REF) Retrofilling
a. Persistent periapical pathosis resulting from an inadequate apical seal that cannot be corrected nonsurgically,
b. Periapical pathosis and blockage of the root canal system that could not be obturated by nonsurgical RCT,
c. Root perforations,
d. Resorptive defects.
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