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Under the limiting oxygen conditions experienced in by vigorous exercise, the configuration of NADH by glycolysis exceeds the ability of the respiratory chain to oxidize it back to NAD+. The pyruvate produced by glycolysis in muscle is then converted to lactate by lactate dehydrogenase, a reaction which regenerates NAD+ and so allows glycolysis to continue to produce ATP. Furthermore, lactate is a metabolic dead-end in which it cannot be metabolized further until it is converted back to pyruvate. The Lactate diffuses out of the muscle and is carried in the bloodstream to the liver. Here it spread into liver cells and is converted back to pyruvate by lactate dehydrogenase. The pyruvate is then transformed to glucose by gluconeogenesis and the glucose is released back into the bloodstream ready to be taken up by skeletal muscle and brain. This cycle of reactions shown in the figure is known as the Cori cycle.
What do you mean by branchial basket? In ascidian adults the pharynx is enlarged to form branchial basket. Pharyngeal openings in wall of the basket allow water to pass through
Q. What is the ADP phosphorylation? What respectively are oxidative phosphorylation and photophosphorylation? ADP phosphorylation is the addition of one inorganic phosphate in
Common Features of Eye and Limb Development A comparison of the embryonic development of the very much different organs, the eyes and the limb, points to various interesting
Uric acid is the main nitrogenous waste product of uricotelic organisms (birds, insects and reptiles), but is also established in ureotelic organisms from the breakdown of the puri
Explain the Mechanism of Drying? Drying as a mechanism, you will realize, involves the removal of free moisture from the surface and also moisture from the interior of the mate
Is the interphase of meiosis different from the interphase of mitosis? The interphase that precedes meiosis is same to the interphase that precedes mitosis. In them the major e
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Explain about the Dietary Fibre? You are all aware that fibre is an important component in the structure of plants. However, fibre as a dietaiy constituent was considered impor
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Role of exercise in the management of diabetes mellitus Exercise is another important component of life style modification. Like diet control, regular exercise is important in
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