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Bleeding on Probing (BOP)
BOP when elicited (notated in patient record as BOP +) after the insertion of a probe into the sulcus with light pressure i.e. 25 N has been shown to detect the presence of an inflammatory lesion in the gingiva around teeth with a normal and healthy but a reduced periodontium. On the other hand an absence of BOP (BOP- ) has been reported to represent periodontal health with a negative predictive value of 98.5 per cent that means the absence of bleeding on probing is a very soundindicator for periimplant health.
A new drug named AGON-CaSR has been developed that is an agonist at calcium-binding sites of CaSRs (Calcium-Sensing Receptors) in plasma membranes of parathyroid gland cells.
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