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Explain about the Thiamin - Vitamin B or aneurin?
Thiamin is one of the earliest recognized vitamins. The chemical structure of thiamine was established by Williams in 1936. The thiamin molecule consists of two linked organic ring structures: a pyrimidine ring bearing an amino group and sulphur - containing thiazole ring linked to the pyrimidine by a methylene bridge. The thiazole ring bears a primary alcohol side chain that becomes phosphorylated to give the thiamin phosphate esters that have cofactor activity. Phosphorylated forms of thiamine include thiamin monophosphate (TMP), thiamin pyrophosphate (TPP) and thiamin triphosphate (TTP). TTP is the most abundant form and constitutes almost 80% of total thiamin.
Name few genetic diseases
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