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Enumerate the stages in trabecular bone surface remodeling
The stages in trabecular bone surface remodeling are:
1. Quiescence - resting state of the bone surface.
2. Activation - recruitment of osteoclasts to a bone surface and signal coupling of osteoblasts.
3. Resorption - removal of bone by osteoclasts.
4. Reversal - osteoclasts stop removing bone and osteoblasts fill the defect.
5. Formation - laying down of bone by osteoblasts
Adverse effects of Lactic acidosis- Lactic acidosis and severe hepatomegaly with steatosis have been reported with use of other nucleoside analogs. The most common adverse effe
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