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Determine the intracellular concentration of TRVA
Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectly conductive to a newly discovered tetravalent anion named TRVA with a valence of -4. The threshold for an action potential in Neuron B is -55 millivolts and the resting potential for Neuron B is -70 millivolts. The TRVA channel in Neuron B is part of an ionotropic receptor with an extracellular binding site for the newly discovered ligand LGD. When LGD binds to its binding site, there is an increase in the TRVA conductance of Neuron B. Neuron A synapses onto Neuron B. Neuron A's neurotransmitter is LGD.
A. The extracellular concentration of TRVA is 10,000 times greater than the intracellular concentration of TRVA. In response to an action potential in Neuron A, there will be an increase in the membrane voltage of Neuron B.
B. The extracellular concentration of TRVA is 100 times greater than the intracellular concentration of TRVA. In response to an action potential in Neuron A, there will be a increase in the amount of intracellular TRVA in Neuron B.
C. The extracellular concentration of TRVA is 10,000 times greater than the intracellular concentration of TRVA. In response to an action potential in Neuron A, there will be an inhibitory postsynaptic potential in Neuron B.
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