Describe the regulation of pyruvate dehydrogenase, Biology

Assignment Help:

Describe the regulation of pyruvate dehydrogenase through covalent modification.

PDH exists in 2 forms :  Inactive, phosphorylated and Active, dephosphorylated. The active form of PDH is phosphorylated by a protein kinase with the help of ATP and Mg++ to  the inactive  form of PDH. Acetyl CoA  and NADH are activators for this action and CoA, NAD+,  and pyruvate are inhibitors. The inactive  form of PDH is dephosphorylated by phosphoprotein phosphatase to the active form in the presence of increased Ca++  ion concentration.

 


Related Discussions:- Describe the regulation of pyruvate dehydrogenase

State in brief about the comprehensive neuropsychology, State in brief abou...

State in brief about the Comprehensive neuropsychology Comprehensive neuropsychology testing needs a combination of Context related ideometric and quantitative psychometric app

Pollination, Pollination Pollination refers to the transfer of pollen...

Pollination Pollination refers to the transfer of pollen from dehiscing anthers to the pistil. Unlike animals, plants cannot move to their mates for sexual reproduction. Henc

Gene recombinations, Which of the recombination process(transformation, con...

Which of the recombination process(transformation, conjugation and transduction) would be most likely to occur in the natural environment?

Male reproductive disorders-cryptorchidism, Cryptorchidism Cryptorchid...

Cryptorchidism Cryptorchidism or incomplete descent of testis or retention of testis in the abdominal cavity occurs in all domestic species but is seen most commonly in stalli

Transplantation, Transplantation - It is implanting of a living or p...

Transplantation - It is implanting of a living or preserved tissue or organ from one site to another side in the same individual or from one individual called donor to recip

How nutritional status influences the age, How nutritional status influence...

How nutritional status influences the age? The nutritional status influences the age-related rate of functional decline in many organ systems in the body. Nutrition is also an

Solid waste management, Solid waste management, Other Management The solid...

Solid waste management, Other Management The solid wastes from a summer camp with 100 children and a staff of 25 are to be collected once per week. If bottles and cans (representi

Define the patient care related to neurological disorder, Define the patien...

Define the patient care related to neurological disorder? A few additional points related to the patient care that need to be kept in mind include paying attention to the patie

Can you explain vestibular system, Q. What is the vestibular system? How do...

Q. What is the vestibular system? How does it operate? The vestibular system is the part of the ear that participates in the regulation and control of the equilibrium of the bo

Thyroid gland, THYROID GLAND - It develops from the endoderm of the ...

THYROID GLAND - It develops from the endoderm of the embryo. Th e thyroid gland is the largest endocrine gland located anterior to the thyroid cartilage of the larynx

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd