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Consider the case of a rare mutant in which the concentration of solutes in the kidney medulla interstitial spaces is equal to the concentration of solutes in the liquid in the lumen of the collecting duct.
The defective molecules associated with this rare mutation are NOT located in the epithelial cells of the kidney collecting duct; the defective molecules are located in other cells of the kidney. In this rare mutant, an increase in the amount of vasopressin that binds to V2 receptors in the kidney will lead to no change in
A. the water permeability of the basolateral membranes of the collecting duct epithelial cells.
B. the amount of water that is reabsorbed into the blood plasma from the lumen of the collecting duct.
C. the net flux of water from the luminal spaces of the collecting duct to the interstitial spaces of the kidney medulla
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