Determine majority of segregation errors in human patients, Biology

Assignment Help:

Which of the following defines why the vast majority of segregation errors in human patients include the two sex chromosomes (XXY, XO, XYY) or chromosome 21 (triple 21)?

A. The centromeres of these three chromosomes lack attachment sites for spindle microtubules therefore leading to a higher than normal segregation error rate.

B. These three chromosomes have the highest probability to be mis-segregated while anaphase I and II of meiosis.

C. Cells are more likely to survive with abnormal numbers of these three chromosomes whereas segregation errors of the other 20 human chromosomes are totally lethal.

D. Chromosome 21 as well as both sex chromosomes lack sequences that are categorized by proteins of the spindle assembly checkpoint (SAC). Thus the cell proceeds to anaphase even if these three chromosomes have failed to reach the metaphase plate.

 


Related Discussions:- Determine majority of segregation errors in human patients

Epigenetics, how does epigenetic controls transcription?

how does epigenetic controls transcription?

Deficiency diseases-iodine deficiency, Iodine  deficiency Iodine is an...

Iodine  deficiency Iodine is an important component of thyroid hormones, which play active role in several physiological process such as control of basal metabolic rate, oxidat

Explain ozone shield, Explain ozone shield? Name two gases that can ca...

Explain ozone shield? Name two gases that can cause damage to this shield. Give one harmful effect of this damage each on plants and animals.

Body fluids, 55yrs old woman had burns and has lost 6% body fluid.She weigh...

55yrs old woman had burns and has lost 6% body fluid.She weighs 50Kg.How much fluid does she need to replace the lost fluid.

Amphibian circulation be classified as incomplete and double, Q. Why can th...

Q. Why can the amphibian circulation be classified as incomplete and double? The amphibian circulation is double because it is composed of pulmonary and systemic circulations r

Phylum porifera, harmful and beneficial usesa of phylum porifera

harmful and beneficial usesa of phylum porifera

Determine the working of law of diminishing return, Determine the working o...

Determine the working of Law of diminishing return According to the 'Law of diminishing return' the increase in the yield by a unit increase of the defi cient factor is proport

Meaning of metabolism, Q. Meaning of Metabolism? Metabolism refers to c...

Q. Meaning of Metabolism? Metabolism refers to chemical changes which absorbed food undergoes within the body cells. Body metabolizes carbohydrate, fat and protein to supply en

Augmentation therapy, Augmentation Therapy: The functional gene is intr...

Augmentation Therapy: The functional gene is introduced in addition to the defective gene endogeneous to the cell(s) in this somatic cell gene therapy,  i.e. the improved  cell

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd