Describe the patent ductus arteriosus, Biology

Assignment Help:

Describe the Patent Ductus Arteriosus?

It is the persistence of normal fetal channel connecting the aorta and pulmonary artery. It accounts for 5-10 per cent of all CHDs. Functional closure of the ductus occurs within 12-24 hours after birth due contraction of the medial smooth muscle. Anatomic closure occurs between 2-3 weeks and is produced by fibrosis of the ductal tissue. In cases where the ductus fails to close normally, blood will shunt from left to light into PA and lungs. This occurs increasingly as the PVR drops and the pressure in the aorta exceeds that of PA. The volume of shunted blood will increase pulmonary blood flow, increase venous return to LA and cause LA /LV volume overload. The flow in the PDA occurs throughout the cardiac cycle. This results in a murmur which starts in systole after S1, peaks at S2 and continues in diastole. This is continuous murmur. The passage of increased blood across the mitral valve produces MDM. The prolonged LV systole results in delayed closure of the aortic valve and a late A2.With large L>R shunts the S2 may be paradoxically split.

1675_Patent ductus arteriosus.png

Figure: Patent ductus arteriosus


Related Discussions:- Describe the patent ductus arteriosus

Show major signs of diabetes, Q. What are the three major signs of diabetes...

Q. What are the three major signs of diabetes? The three major signs of diabetes mellitus are known as the diabetic triad- polydipsia, polyuria and polyphagia. Polyuria is t

Main phases and clinical manifestations of schistosomiasis, Q. What are the...

Q. What are the main phases and clinical manifestations of schistosomiasis? The Schistosomiasis has acute and chronic phases and Days after the infection the cercarial dermatit

Explain what is correction of hypovolemia, Explain what is Correction of Hy...

Explain what is Correction of Hypovolemia ? Intravenous fluids should be given to correct hypovolemia and optimize preload to the heart. This is particularly important in sept

What would the volume for reaction, The component is DNA. The stock concent...

The component is DNA. The stock concentration is 10mg/ml and the final concentration/amount is 25ug. What is the volume for 1 reaction? For 5 reactions?

State the term - infection, State the term - Infection Infection is th...

State the term - Infection Infection is the invasion of the body by disease-producing (pathogenic) microorganisms and the reaction of the tissues to their presence and to the

Essentials of Human Diseases and Conditions, How do pathological conditions...

How do pathological conditions affect homeostasis of your body?

Explain canal obstruction - non-surgical endodontic, Explain Canal Obstruct...

Explain Canal Obstruction - Non-surgical Endodontic Retreatment     File work shorter than the normal apical and feel a great resistance to reach the true length a. A retain

Iron deficiency anaemia, Iron Deficiency Anaemia   This is the most com...

Iron Deficiency Anaemia   This is the most common nutritional and haematologic disorder  in infancy and chhildhood in developing countries. It is caused by lack of sufficient i

Define reagents for seliwanoff test, Define Reagents for seliwanoff's tes...

Define Reagents for seliwanoff's test? - Sugar solutions of glucose, fructose, galactose, lactose, maltose, sucrose and starch - Resorcinol in dilute hydrochloric acid (1:

Drinking & driving, DRINKING & DRIVING - It should not be mixed because...

DRINKING & DRIVING - It should not be mixed because alcohol - 1.       Impairs ability to judge distances. 2.       Reduces capacity to coordinate limb muscles. 3.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd