Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Define Proteins as biological buffers?
Proteins have the ability to accept or donate hydrogen ions and by doing so they serve as biological buffers. In blood, there are three important buffering systems - plasma proteins, haemoglobin and carbonic acid bicarbonate. The equilibrium reactions for each of these buffering systems are as follows:
The first of these buffering systems, the plasma proteins, functions as a weak acid1 salt buffer when the free carboxyl groups on the protein dissociate, or as a weak base/salt buffer when the free amino groups dissociate. Although the buffering ability of the plasma protein is extremely important in maintaining blood pH, it is not as important as the other two systems, the second buffering system, carbonic acid-bicarbonate, is extremely effective because there are reactions which follow this equilibrium which will regulate either acids or bases.
The H2CO3 level in plasma never goes too high because it is in equilibrium with CO2 (H2CO3 → CO2 + H2O), which is expired by the lungs. In blood, this equilibrium proceeds very quickly because of the presence of carbonic anhydrase, an enzyme found in red blood cells which catalyze it. If the carbonic acid-bicarbonate reaction goes in the opposite direction, the concentration of the HCO3- so formed will be regulated by the kidneys. The third important buffering system in blood results from haemoglobin. Haemoglobin has six times the buffering power of the plasma proteins. It functions well as a buffer because it is present in large amounts, it contains 38 histidine residues (Histidine residues are good buffers because they can dissociate to H+ and the imidazole group) and because haemoglobin exists in blood in two forms, reduced haemoglobin and oxy haemoglobin. It is thus a weaker acid and a better buffer.
Explain about the Diabetes mellitus? You are aware that diabetes may be diagnosed as an exaggerated response in blood glucose concentration following ingestion of a fixed amou
In these disinfectants, iodine is incorporated along with a detergent. They are not as effective as hypochlorites against bacterial spore but also get inactivated in the pres
Q. Are the extraembryonic membranes the same in all vertebrates? The presence of each extraembryonic membrane differs according to the vertebrate class. In amphibians and fi
What are the uses of construction of a retaining wall? The retaining wall is constructed whenever space requirement do not allow the natural slope to be formed for an excavatio
Q. First type of rheological model? This method establishes relation between the pressure gradient and the volume rate of flow. Here, the piston measurement is used to measure
Define role of Vitamin D in controlling gene expression? Vitamin D is a secosteroid that is metabolically activated and degraded through the actions of three cytochrome P450 hy
Ammonification Many heterotrophic bacteria actinomycetes and fungi in soil and water metabolise the organic nitrogen and release it in an inorganic form as ammonia. This proce
PHASES OF NURSE-PATIENT RELATIONSHIP: Kapoor, Bimla (1994) has listed four phases of nurse patient relationship which are explained below while describing the phases she has
Q. Generally how does a male animal realize that the female is receptive to copulation? In most vertebrate species with internal fecundation the females have reproductive cycle
What is prophylaxis? Prophylaxis are measures taken to stop diseases. For instance, the use of condoms in sexual relations is a prophylaxis against contamination by agents that
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd