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Q. Define osseointegration and its theories?
Osseointegration implies that "it is a contact established without interposition of non bony tissue between normal remodeled bone and an implant at the light microscopic level, entailing a sustained transfer and distribution of load from the implant to and within the bone tissue". Osseointegration can also be defined as "a direct structural and functional connection between ordered, living bone and the surface of a load carrying implant" Creation and maintenance of osseointegration, therefore, depends on the understanding of the tissue's healing , repair, and remodeling capacities.
Branemark's Theory of Osseointegration
Branemark proposed that implants integrate such that the bone is laid very close to the implant without any intervening connective tissue. Branemark also stated that the implant should not be loaded and left out of function during the healing period for osseous integration to occurWeiss's Theory of Fibroosseous fixation Weiss' theory states that there is a fibro-osseous ligament formed between the implant and the bone and this ligament can be considered as equivalent to the periodontal ligament found in the gomphosis. He defends the presence of collagen fibers at the bone-implant interface. Biointegration - dePutter observed that there are two ways of implant anchorage or retention: mechanical and bioactive.
Mechanical retention refers to the metallic substrate systems such as titanium alloy. The retention is based on the undercut forms such as vents, slots, dimples, screws etc and involves direct contact between the dioxide layer on the base metal and bone with no chemical bonding. Bioactive retention is achieved with bioactive materials such as hydroxyapatite (HA), which bond directly to the bone, similar to ankylosis of natural teeth.
Nucleosides : compounds formed from a nitrogenousbase and a penstose sugar.
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