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Modulation of the transcription of cell cycle proteins?
The 1,25-(OH),D compound (calcitriol), is present in the blood complexes to the vitamin D-binding protein, a specific a-globulin. Calcitriol is believed to act on target cells in a similar way to a steroid hormone. Free hormone crosses the plasma membrane and interacts with a specific nuclear receptor known as the vitamin D receptor, a DNA-binding, zinc-finger protein with a relative molecular mass of 55,000. This ligand-receptor complex binds to a specific vitamin D-responsive element and, with associated transcription factors (e.g. retinoid X receptor), enhances transcription of mRNAs which code for calcium-transporting proteins, bone matrix proteins, or cell cycle-regulating proteins.
Bone Remodeling Bone remodeling differs from the other means of bone structure alteration in that osteoblasts and Osteoclasts do not act independently but are coupled and bone
Molecular Biology Transgenesis: pro-nuclear injection of isolated gene into fertilised egg cell, cell divides to form embryo, then embryo implanted into surrogate.
Why is sex-linked inheritance an example of nonmendelian inheritance? The Sex-linked inheritance is a kind of nonmendelian inheritance because it opposes Mendel's first law, wh
Wet and dry thermal treatment Wet thermal treatment: it is based on exposure of shredded infectious waste to high temperature, high pressure steam. It is inappropriate for the
1. The transcription and replication of DNA requires a multitude of protein complexes a. Describe the events that occur during the initiation of transcription of eukaryotic prot
Q. Signs of constrictive pericarditis? 1) Jugular venous pressure (JVP) is elevated in all patients of CP which reflects the elevated diastolic pressure of the right atrium.
Nucleus - Largest component of the cell. Nucleus is double membrane bound dense protoplasmic body that controls cellular metabolism, enclose all the genetic information,
why the small intestine is longer in herbivores as comparison to carnivores animals
TEMPERATURE Temperature is a major physical environmental factor which profoundly influences the vital activities of living organisms like, metabolism, growth and reproduction.
What is the salivary digestive enzyme? Which type of food does it digest and into which smaller molecules does it transform the food? The salivary hydrolase is called as saliva
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