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Modulation of the transcription of cell cycle proteins?
The 1,25-(OH),D compound (calcitriol), is present in the blood complexes to the vitamin D-binding protein, a specific a-globulin. Calcitriol is believed to act on target cells in a similar way to a steroid hormone. Free hormone crosses the plasma membrane and interacts with a specific nuclear receptor known as the vitamin D receptor, a DNA-binding, zinc-finger protein with a relative molecular mass of 55,000. This ligand-receptor complex binds to a specific vitamin D-responsive element and, with associated transcription factors (e.g. retinoid X receptor), enhances transcription of mRNAs which code for calcium-transporting proteins, bone matrix proteins, or cell cycle-regulating proteins.
Define Health Benefits of Other Dietary Factors with Antinutritional Effects? Despite the predominantly nutritional antagonistic effects of the factors described above, there i
Regulation of HMP Pathway The following factors play an important role in regulation of HMP pathway: a) The first reaction of this pathway catalysed by glucose-6-phosphate
Explain the Proteus - Characteristics of Bacteria? It is gram negative, non-sporulating rod, which is characterized by rapid motility (peritrichous flagella) and swarming type
Ganciclovir (Cytovene) IV ganciclovir is approved for both induction and maintenance treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients and for prevent
Economic Significance - Conservation of Wildlife Certain wild species are important because of their actual or potential economic value to people. Wildlife resources provide p
Before Abutment Connection There can be wound dehiscence, and the presence of signs of infection such as swelling, fistula, pain prior to stage to surgery. It is important t
Oxidised starch Oxidised starch finds a number of uses in the food industry where a neutral tasting, low viscosity 'body builder' is required as in lemon curd manufacture, in s
What are the principal sources of excessive nitrate and phosphate in rivers and lakes?
Q. Define the Risk reduction in cardiovascular disease? Ans. Weight loss by caloric restriction diets has been shown to decrease plasma CRP levels. Additional data indicat
Q. Explain the Spring clip model? The spring clip model differs from the spring model in a way that the force applied is comparatively slower. This also depicts elasticity or p
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