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Q. Define Low - density lipoprotein?
Ans.
LDL is the major cholesterol-rich lipoprotein carrying approximately 70 per cent of plasma cholesterol. It serves to transport cholesterol to peripheral cells.
The Nobel laureates Brown and Goldstein identified the LDL receptor that recognizes apoprotein B100 of LDL particles (Brown and Goldstein, 1986). The receptors are large glycoproteins situated on the surface of cells in specialized areas termed coated pits. Coated pits are organelles necessary for the internalization of macromolecules. The LDL receptor gene has been cloned and localized to the short arm of chromosome 19.
The clinical relevance of this structural detail of the receptor will be appreciated when the inborn error of cholesterol metabolism called familial hypercholesterolaemia is discussed. In this condition there are defects in the gene coding for the receptor.
What is condition for the Mendel's second law to be valid? The Mendel's second law is only valid for genes located in various chromosomes. For genes situated in the similar chr
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Q. What are varices? Why are they more common in the inferior limbs? Varix means abnormal enlargement of veins and the Varices occur when excessive pressure against the normal
Q. Define Bioinert materials? Bioinert materials are chemically inert in the body and exhibit minimal chemical interaction with adjacent tissue such as titanium and alumina (Al
Q. Pathophysiology of aortic regurgitation? Left ventricle responds to chronic aortic regurgitation by chamber dilatation and an increase in its compliance so that end diastoli
Express the term ctene. This unique locomotory structure is found in Ctenophora and is made up of fused cilia arranged into flattened plates. Ctenes are then organized into eig
Formation of Gemmules Throughout the formation of gemmules, masses of food - laden amoebocytes called archaeocytes feed on other cells and lay down in within them. They get s
Treatment options for ailing and failing implants are varied. The clinician should start conservatively and progress to more aggressive therapy. The overall goal of therapy is
What are the Chemical requirements of implant materials It must withstand corrosion by body fluids It should not have any direct or indirect negative effects on the surround
Define Assessment of Magnesium Status and Dietary Requirements? In order to estimate Mg requirements and establish relationship between magnesium intake and deficiency, it is
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